The cat as a model for human obesity and diabetes

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Birgit

Birgit

Member Since 2021
Hi, I am new to the forum. I apologize for not having introduced myself here. I have on the FB group.
I wanted to share this research article because when posting on the FB group I did not get much of a response so far and I was hoping for some discussion.
As a previous type 2 diabetic I am hoping to focus on how to prevent/reverse type 2 diabetes in cats and I thought the above article had some helpful info, in particular the role of insulin resistance and obesity as a predictor of many (but not all) cases of type 2 diabetes in cats.
https://www.ncbi.nlm.nih.gov/pmc/ar...jtjaC5_NdQrVxYUOx64m93Qxeocf9nh91ng5sUP8vDHts
 
There's a research vet in Florida that focuses on diabetes. Although from what I've read of his he's not trying to reverse, but find a new way to treat feline diabetes. If I remember correctly one of his research papers was about a possibility of remission through a one-time shot. It's been a long time since I've read his work, and I may be wrong about that, but I'll try to find it for you. Here's his bio at UF

The Diabetes Clinic team is led by Chen Gilor, DVM, PhD, DACVIM. Dr. Gilor is a Diplomate of the American College of Veterinary Internal Medicine and has a PhD in feline diabetes from the University of Illinois at Urbana-Champagne. He is a world-renowned expert on feline and canine diabetes, especially in the area of insulin therapy and insulin-alternatives. He advanced the field by publishing more than 50 scientific papers on diabetes and other metabolic diseases, many of which focus on novel therapies and diagnostics. He is a frequent speaker at national and international scientific forums and continuing education meetings. Dr. Gilor also serves as a consultant to numerous biotech and pharmaceutical companies and is currently the Vice President of the Society for Comparative Endocrinology.

https://smallanimal.vethospital.ufl.edu/clinical-services/internal-medicine/diabetes-clinic/
That links to the page
 
Thanks so much, I will check that out. The article I linked above is also from someone at UofI Urbana-Champagne.
 
Thanks for posting the link. My only observation is that the research is quite dated -- almost 10 years. If the research was that important, it would have been more mainstream by now.

The one other thought I have is that. unlike with humans, cat's islet cells (the cells that produce insulin) can recover and begin to produce endogenous insulin again. This is not true for humans.
 
Sienne and Gabby (GA) said:
Thanks for posting the link. My only observation is that the research is quite dated -- almost 10 years. If the research was that important, it would have been more mainstream by now.

The one other thought I have is that. unlike with humans, cat's islet cells (the cells that produce insulin) can recover and begin to produce endogenous insulin again. This is not true for humans.
Click to expand...
From my understanding islet cells can recover in humans with type 2 diabetes but not with type 1. Dr. Jason Fung has done a lot of research on that and his assumption seems to be that it is the fat deposits on the pancreas that limit the function of beta cells. I can't remember details at the moment but here is a podcast episode on this topic.
https://peterattiamd.com/jasonfung/
 
Birgit said:
From my understanding islet cells can recover in humans with type 2 diabetes but not with type 1. Dr. Jason Fung has done a lot of research on that and his assumption seems to be that it is the fat deposits on the pancreas that limit the function of beta cells. I can't remember details at the moment but here is a podcast episode on this topic.
https://peterattiamd.com/jasonfung/
Click to expand...
Islet cells recovering = true remission??
 
I don't have anything to contribute, but you might want to check out the "Think Tank" forum here. It seems to be specifically targeted toward the discussion of the topics you're interested in :-)
 
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