I looked under drug interaction action checker for cats, I called a 24 h vet in another town and they told me not to give any more and they would be glad to see him, but I am not up to driving by myself out of town tonight.
On drug interaction for cats. Buddy has been taking Ondansetron prescribed by a previous vet, he has been sick and would not eat so I gave him the Miratzapine prescribed by his vet. He started acting funny and I know Ondansetron is weird. It said the 2 should not be taken together. How did your cat act.
Yes, he has and he got the meows.
Please provide the link.
I don't have a link. I looked under drug interactions for cats and Mitrazapine.
I did not notice any behavior differnences. He had been a bit off altogether, but I attributed that to his almost dying from a kidney infection. He's doing much better now. What was Buddy doing that you noticed?
He has been taking Ondansetron prescribed by a previous vet and he would not eat so I gave him 1/2 -15 mg mirtazapine. He started acting weird, not just the MEOWS, but hiding, his eyes bugging out and just not his self.
Hiding, eyes bugging out and just acting strange. They are not to be taken together.
On the top of your Chrome or Google webpage, there will be a "history" of sites you have looked at today. Click on it and scroll down for the page you checked.
That sounds like a lot.
There is no one but my 97 year old Mother who lives with me and she is sick. I have called a 24 hr vet in another town who told me they if he started throwing up, diarrhea and a few other things to bring him in. He seems to be acting better, I thought if someone else had used both they would have an idea. He will not get anything else until in the morning.
That is what was prescribed by his doctor, it is to be taken every 3 days. Maybe your pill was a larger mg.
Bud
Thank you, I hope so too. Buddy has been really sick and in the hospital twice for several days in the last 2 or 3 weeks. His pancreatitis was so bad, that he had Peritonitis. I have been sooo worried about him, I love him a lot.
I have 1/4 of a Cyproheptadine, that is why I was giving the Mirtazapine. My new vet uses only Mirtazapine and cerenia, not ondansetron. I called the local hospital and they said ondansetron stayed in your system 10 hrs and the 10 hrs is past. I have some Mirtazapine from my old vet and the mg are the same as my new vet. I did not know that cypro would reverse mirtazapine. I also have Loratadine 10 mg (spelling) for myself.
I took Buddy to see his vet today, just to be on the safe side and he is doing fine. The vet said to not give him any more mirtazapine for a while. I did call the office of his former vet to see if they will sell us some cyproheptadine (this is what he has always taken) This vet also prescribes Mirtazapine 15 mg take 1/2 pill every 3 days.I was just thinking the same, Nan
Teresa, I've been looking all around today and can find nothing that recommends a 7.5mg dose of mirtazapine for any size cat at any frequency. Everything that I see acknowledges a 3.75mg dose (1/4 of 15mg), but also says that 1.88mg (1/8 of 15mg) is still effective but with fewer side effects. This particular article gives the frequency of 1.88mg dosing as every 24 hours for young, healthy cats, and every 48 hours for older/liver/kidney cats. Especially with what happened last night, I really urge you to press your vet for cyproheptadine, or compounded 1.88mg mirtazapine capsules (since it is almost impossible to split a pill into eighths) or transdermal mirtazapine. Personally if I were you, I would lean towards crypo instead.
Here's the article that I recommend you read: https://www.americanveterinarian.com/news/wvc-2017-mirtazapine-for-appetite-stimulation-in-cats
But here is the summary:
"In conclusion, mirtazapine works as an appetite stimulant in cats. Current dosing recommendations for mirtazapine in young, healthy cats is 1.88 mg/day. In older cats and those with chronic kidney or liver disease, 1.88 mg can be given every 48 hours. This dose, while effective, results in fewer undesirable side effects than the traditional 3.75-mg dose."
I guess 7.5 over 3 days would b 2.5 mg a day.
I m having problems getting him to eat, if he was not diabetic I would not worry about it, but when you need to go somewhere I can't leave unless I know he has ate. I have phoned his former vet's refill line and asked for cypro. I will not give the mirtz, unless something changes. That is the 2ndtime he has taken mirtz.
The dose might have been a problem, but Ondansetron is also a problem. Ondansetron is not to be taken with a lot of things, includingHi. I'm going to attach some links. My T was prescribed the human/pill form of Mirtazapine years ago the way it was traditionally, take 3.75mg (1/4 tablet every 72 hours). He had no issues. Fast forward years later & we gave him the same dose, 1/4 tablet & he was agitated, pupils dilated, meowing etc.. Turns out there have since been studies to show that a lesser dose-1.88-was just as effective but much fewer side effects & metabolized better by cats. Additional studies showed that part of the issue may have been the initial studies were done in healthy cats.
https://www.americanveterinarian.com/news/wvc-2017-mirtazapine-for-appetite-stimulation-in-cats
In 2018, a newer version of Mirtazapine was created & FDA approved specifically for cats. It's called MIRATAZ. Its a transdermal ointment & therefore easier to get a smaller dose. It is the first & only FDA approved drug specifically for felines for the management of weight loss. Dose indication is a 1.5 inch ribbon applied to the inside of the ear (equivalent to 2mgs):
https://kindredbio.com/mirataz/mech...MI4KzW3db_4wIVk1qGCh0lxAXhEAAYASAAEgIGvPD_BwE
I would still be careful & speak to your vet & then if you try Mirataz, watch for any issues as your cat may have an issue with the drug no matter what formulation or dose. Most likely, & hopefully, it was the dose vs the drug
I picked up 10 Cyproheptadine today from Buddy's former vet, we may start seeing her every now and then. The problem is, she only is in a few days a week and I need to be able to get my cat's seen more often. Wonder how much 1.88 mg would be of a 12mg Mirtz.
I have not had a chance to reply, but I had no idea about the dose of mirtazapine being so high, especially since this came from 2 vets. If Buddy ever has mirtazapine he will get 1/8 of a 15mg pill. I also saw somewhere that you could use the cyproheptadine to reverse the mirtazapine like you said. Thank you, for the needed info, Sorry it took me so long to reply.
Buddy is not feeling very well tonight, he has a serious problem with pancreatitis and that is why I was giving him mirtazapine, but we now have some cypro. Tomorrow is a new day and I am hoping things will look up. I appreciate all the info.
Sounds good.