What do you guys mean by holding the dose too long? I will try and get some night readings, right now he is a bit scared of me. Also I first started with the needles that go on the pen and then I noticed that sometimes nothing was coming out. So I switched to syringes. However I only had a pack of ten and have ordered more and they don't get to me until Tuesday. So I am a little nervous because I had some u-100's that I use to give b12 shots for but their marking are only at the 2 unit mark, so I had to eye 1 unit tonight, I am hoping I gave the right amount but it was very hard to eye that. Buddy's vet is looking at that curve tomorrow and I am thinking she will have me up it to 1.5 units....So I guess I will try the tight regulation method. A lot of it does not make any sense to me. And I have been very nervous, at the emergency vet he had slight ketones in his urine but I was able to test it today at home and it showed none so I am thankful for that. But right now he is very sick and I would like to get him to feeling better because it is breaking my heart.