OK, guys, while we have a semi-quiet moment I need to know what the protocol calls for. In PZI-ville we'd shoot at +6 or beyond if at 150 or over. What's Lantus' duration (like this isn't diabetes and I'm going to get a consistent answer)? How do I establish the nadir? Ah, I see you're reading my mind. Well, I think the infection could definitely have been playing havoc with his numbers. He was on an antibotic for 10 days too. Clindamyclin Hydrochloride (1.5ml every 12 hours). Last dose was last Monday (4/12). Since then he's done things like 309 at +11.5 and 171 at +23 or 236 at +24 and 79 at +17 after being at 74 at +7.5. His last PZI dose, however, was way over the norm at 11U. Sammy usually doesn't tolerate 10 and above well and has rarely needed it. He probably never had that much ever until this year.