? 10/29 Eddie: Question regarding antibiotic pulse therapy

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Jodey&Eddie&Blue

Member Since 2021
Hello Everyone

I generally post in the forum dealing with insulin protocols and DM.

Eddie’s situation is that he has acromegaly although he’s also had hypophysectomy to remove tumour snd pituitary. He’s also had radiation. The situation is that he is at great risk for anesthesia and has dental problems that require a specialist and anesthesiologist and that’s are 5 hours away by car on roads not driver-friendly in winter.

The aim is to keep his dental issues- inflammation and infection—controlled until spring, I.e, June when roads are ok and we can get to the specialist. You will see from his spreadsheet that this past week his BG numbers are quite stable and encouraging given that he was on 7 days of Clavaseptin (1.25mg BiD).

The vet with whom I'm working is quite receptive to trying out the protocol but has no experience with it and has found negative responses in various places she's checked. But she is not resistant at all to trying it out.
She was suggesting 7 days on and 21 days off in order to prevent antibiotic resistance as much as possilbe.
Again, please note: this protocol would not be in perpetuity but just until June of next year.

I’m seeking your thoughts on the protocol in general if you have experience of it. What type of antibiotic was used.

Again Eddie's vet is trying to find info and is willing to hear (which is rare) what I can learn here at FDMB.

Thank you!
 
Has the vet been in touch with the dental specialist you use? That would be my first call. There's also a veterinary dental professional group. Checking with them for a consultation may be a possibility. The vet school at Cornell has a Feline Health Center. They do phone consultations.
Yes, the vet is in touch with the specialist or at least has tried to be. She said she sent them a lengthy email last week and was waiting for a reply but since she hasn't heard will phone them tomorrow morning.
Thanks so much for the tip re: Cornell. I will certainly pass this over to the vet!
 
I don't know if Cornell offers vet-to-vet consults. They will consult with owners. It won't hurt to check things out. Cornell may be likely to do so but I would suggest having your vet call the vet hospital pharmacy. The pharmacists will have the expertise to know all about pulse administration of antibiotics.
 
I know this is a very old post (2018} but thought I would show you , I see it's a diffetent antibiotic though
FYI: We did a pulse therapy using clindamycin for several years for recurring gingivitis. Started with 5 days then soon went to 7 days every month. My vet didn't think it would help, but I asked him to humor me. I also asked him what did we have to lose? We didn't want to anesthetize her any more than we had to because of other health issues and there were other abs available for oral use if she happened to become resistant. My vet was pleasantly surprised at how well pulse therapy worked for Alex.


Also see post #7 and #9 on this thread
https://www.felinediabetes.com/FDMB...biotics-teeth-and-nausea.277949/#post-3075097

Here is another one post #23
https://felinediabetes.com/FDMB/threads/when-to-increase.265395/#post-2973212
 
Last edited:
Hello Everyone

I generally post in the forum dealing with insulin protocols and DM.

Eddie’s situation is that he has acromegaly although he’s also had hypophysectomy to remove tumour snd pituitary. He’s also had radiation. The situation is that he is at great risk for anesthesia and has dental problems that require a specialist and anesthesiologist and that’s are 5 hours away by car on roads not driver-friendly in winter.

The aim is to keep his dental issues- inflammation and infection—controlled until spring, I.e, June when roads are ok and we can get to the specialist. You will see from his spreadsheet that this past week his BG numbers are quite stable and encouraging given that he was on 7 days of Clavaseptin (1.25mg BiD).

The vet with whom I'm working is quite receptive to trying out the protocol but has no experience with it and has found negative responses in various places she's checked. But she is not resistant at all to trying it out.
She was suggesting 7 days on and 21 days off in order to prevent antibiotic resistance as much as possilbe.
Again, please note: this protocol would not be in perpetuity but just until June of next year.

I’m seeking your thoughts on the protocol in general if you have experience of it. What type of antibiotic was used.

Again Eddie's vet is trying to find info and is willing to hear (which is rare) what I can learn here at FDMB.

Thank you!
I see Suzanne has used pulsing AB but it was a different antibiotic but maybe she has something to add
@Suzanne & Darcy
 
I know this is a very old post (2018} but thought I would show you , I see it's a diffetent antibiotic though
FYI: We did a pulse therapy using clindamycin for several years for recurring gingivitis. Started with 5 days then soon went to 7 days every month. My vet didn't think it would help, but I asked him to humor me. I also asked him what did we have to lose? We didn't want to anesthetize her any more than we had to because of other health issues and there were other abs available for oral use if she happened to become resistant. My vet was pleasantly surprised at how well pulse therapy worked for Alex.


Also see post #7 and #9 on this thread
https://www.felinediabetes.com/FDMB...biotics-teeth-and-nausea.277949/#post-3075097

Here is another one post #23
https://felinediabetes.com/FDMB/threads/when-to-increase.265395/#post-2973212

Diane, thank you, this is really helpful.
 
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