6-20 Gizmo AMPS=311; +3=372; +6=277; +8.5=272; PMPS=349; +2=319

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Chubba (GA)

Chubba (GA)

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Condo - http://www.felinediabetes.com/FDMB/threads/6-19-gizmo-amps-343-4-366-7-398-pmps-372.179455/

PM Cycle:
PMPS = 372
+2 = 344
+7.5 = 334 (I didn't wake up as early as I wanted to ... was shooting for a +5-7)

AMPS = 311

Cycle 6 of the dose increase. This is the cycle we saw lower numbers on the last dose increase. Hopefully. The petsafe 5 was supposed to be delivered today, but when I checked this morning it is now coming through the post office instead of fed ex. So it will be another 2 days! ☹️ I'm so frustrated that they changed the delivery date.
 
Not sure where the 372 came from at +3. Definitely not the number I was expecting. What's going on with you, Gizmo?
 
After looking at Gizmo's SS are you sure that he is not having another health issue? With those numbers high and flat and when the depot builds and dumps you would think the numbers would come down. I saw you had him on AB and I wonder if whatever he was on them for is not cleared up?
 
I was told once Bronx got to 6u to get the acro & IAA tests done. So let's hope he doesn't have to go that far.
 
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DebG said:
After looking at Gizmo's SS are you sure that he is not having another health issue? With those numbers high and flat and when the depot builds and dumps you would think the numbers would come down. I saw you had him on AB and I wonder if whatever he was on them for is not cleared up?
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He has always been a very healthy cat. Never any issues until the diabetes. Actually Feb 2017 was the first time he was ever at the vet besides for vacccations. The vet has put him on AB twice as a precaution when his numbers were higher. He never said that he had any type of infection. His teeth are good also. I suppose it is possible, but given his recent vet check-ups I would think not.
 
Here is some info, MSU does both tests so vet just has to send blood to one place. When Bronx reached 6u and was still flat & high, I got the tests. Bronx was dx with acro, some kitties here have both acro & IAA, some just IAA. But let's hope for now you don't get to 6u.

http://www.felinediabetes.com/FDMB/...-other-high-dose-conditions-what-we-know.375/

Cats with Insulin Auto Antibodies (IAA)
http://petdiabetes.wikia.com/wiki/Insulin_antibodies
When insulin is injected into a diabetic cat, the body views it as a foreign substance and the immune system sets out to destroy the "invader" insulin, just as it would destroy cold and flu viruses. When this happens to injected insulin - most of it never reaches the bloodstream thus being unable to control blood glucose. Insulin doses may be increased but the immune system only goes into higher gear and continues to effectively destroy any additional injected insulin. Over time this becomes officially known as insulin resistance.
 
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Hopefully, we won't get there. I'm hopeful that the +3 test was just flawed. I'm going to test again at +6 (1 hour).
 
+6 = 277 Finally!

According to TR, I should increase by 0.25 units tonight. I'm unsure about this since it seems like when I increase he has flat pink cycles for the next few days. Should I wait a day or two to see if this dose will bring him down some more?
 
It can take a few days after an increase for the depot to build up. I would say if you don't see a blue this cycle, an increase is warranted. At some point the increases can be .5 instead of .25. Nice to finally see a yellow!
 
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With numbers this high, I think you should continue to increase every six cycles. I think it is just NDW that causes the flat pink cycles, not anything to make you hesitate to increase. Gizmo definitely needs more insulin.

Is Gizmo eating well? Drinking or peeing a lot? Have you ever tested him for ketones?
 
Bronx's dad said:
It can take a few days after an increase for the depot to build up. I would say if you don't see a blue this cycle, an increase is warranted. At some point the increases can be .5 instead of .25. Nice to finally see a yellow!
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I thought 0.25 increase since he saw a nadir between 200-300.
 
Tricia Cinco(GA) & Harvey said:
With numbers this high, I think you should continue to increase every six cycles. I think it is just NDW that causes the flat pink cycles, not anything to make you hesitate to increase. Gizmo definitely needs more insulin.

Is Gizmo eating well? Drinking or peeing a lot? Have you ever tested him for ketones?
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Gizmo always eats well. He usually starts pestering for food about an hour before food time. I'm wondering if I am feeding him enough. He currently gets 1.5 cans (5.5 oz) a day. He weighs around 14lbs and has been staying pretty consistent at that weight. He still drinks more than he used to. Definitely still more pee in the litter box also (although I have 2 cats, so that one is a little harder to say for sure). I thought the vet tested him for ketones, but now my husband said he doesn't think so. I was at work when he was diagnosed. I have never tested him at home. Not really sure what that involves?
 
Chubba said:
I thought 0.25 increase since he saw a nadir between 200-300.
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Yes, 0.25 increases for now. Once Bronx hit about 5u, I did start increasing 0.5u When we hit 10u, the increases were 1u, etc.. The % increase still remained about the same 10%. (10% 0f 5 is .5, 10% of 10 is 1, etc...).
 
Bronx's dad said:
And I didn't even see a yellow until we were at 8.5u. Gizmo's chart looks a lot better than Bronx's did at 3.75u.
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Wow ... I just relooked over Bronx's spreadsheet. You two have had quite a journey. I have to remember to be patient, but I get worried when I think it isn't working.
 
I got busy and didn't have a chance to update.

+8.5 = 272
PMPS = 349

Increased to 4 units. Going to update spreadsheet now. Gizmo must be feeling pretty good now (+1.5), he is running around the kitchen chasing a toy like a crazy cat. Haven't seen him play like that in quite a while. Hopefully that's a good sign!
 
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