? Assistance with Vetsulin Needed - ? too high a dose

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@Kako, if you don't get lucky with finding your Lantus via the Supply Closet remember it's much cheaper to buy from Marks Marine Pharmacy in Canada.


I'm very glad you found FDMB, Kako, and I hope you're not feeling quite so scared now.

:bighug:


Mogs
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You always relax me. :) Not scared at all now since Tux's BG is no longer 700's and 600's! Please advice me on adjusting Lantus dose starting a day after tomorrow. :)
 
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But what I have seen of Prozinc up to now ....
Um..... Just had to comment on this, because the inference (intended or otherwise) is that Lantus is somehow 'better' than Prozinc. And I wouldn't want others reading this thread to get that impression.
Prozinc has been in use on this forum for a long time, and has been a very good insulin for many cats. Others have done well on other PZI insulins.
And quite a few cats do very well on Levemir (some after switching from Lantus).

There is a saying here that 'The best insulin is the one that works best for the cat'. But we have no way of knowing in advance which insulin that will be.

Eliz
 
@Kako

Good luck with the change of insulin, Kako! :bighug:
There are many experienced Lantus users here who will be able to advise you on how to help your gorgeous Tux to feel better.
Keeping fingers and paws crossed that things improve for him really soon.

Hugs,

Eliz
 
There is a saying here that 'The best insulin is the one that works best for the cat'. But we have no way of knowing in advance which insulin that will be.
This is true, Eliz, and I agree with you wholeheartedly that an individual cat may have a much better response to one particular insulin over another. However, if I were a relative novice and I was considering a switch from Caninsulin/Vetsulin to a different insulin one of the major factors I would take into consideration when making the decision as to which insulin to try next would be evidence of improved likelihood of remission rates, doubly so if I were under significant financial constraints and could not afford the luxury of a 'suck it and see' approach to treatment; I'd want my cat to get the best bang possible for my limited bucks. I'd also take into consideration the experiences of others who had at one time treated their cats with the insulin I was currently using but who had had demonstrable success with a different insulin. If more of them had better success with Lantus then that is what I would choose. I would also give weight to the experience-based opinions of highly knowledgeable people who were very active members of reputable diabetic cat fora because they would have had exposure to a wealth of evidence, albeit technically anecdotal, of performance of different insulins and they might give me a valuable steer as to the best insulin to try next based on the success rates of the members.

It's true that many cats do great on ProZinc but, personally speaking, if I were trying to choose between ProZinc and Lantus I would go for the Lantus: both would be unknown quantities at outset but there is scientific evidence which has demonstrated a not insignificant increase in the likelihood of a cat achieving remission on Lantus compared to ProZinc and I would therefore choose the former because statistically it would give my cat a better chance of becoming a diet-controlled diabetic. The only major counter to that would be if my life circumstances were such that managing the consistent dosing necessary to optimise the benefits of a depot insulin was problematic, in which case I might then plump for one of the in-out P insulins because of the greater dosing flexibility they offer.


Mogs
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Rosa really didn't get check-ups specifically for her diabetes at the vet. I spent my money on testing supplies so I could get accurate numbers at home instead of having them run curves. What I did was email them the link to Rosa's spreadsheet so they could see the numbers I was getting and what I was doing with her dose. The real costs of diabetes were around the time of her diagnosis. But now she has CKD, so she has to have very regular blood work while we try and find a way of getting the best control of that we can...and some of the meds she's on now are actually more expensive on a daily basis than Lantus too!
I will include Rosa in my prayers. :)

Testing costs... yes! :arghh: One AlphaTrax strip costs the same as two cans of Friskies. :eek: I've used 100 strips within 3 weeks because I wasted a lot of them the first two weeks. I hardly waste now and I've ordered one bottle of FreeStyle strips for less. It's on it's way. :)
 
I will include Rosa in my prayers. :)
Thank you so much. I really do appreciate that more than you can possibly know. :)

Testing costs... yes! :arghh: One AlphaTrax strip costs the same as two cans of Friskies. :eek: I've used 100 strips within 3 weeks because I wasted a lot of them the first two weeks. I hardly waste now and I've ordered one bottle of FreeStyle strips for less. It's on it's way. :)
The strips are a horrible price - really crazy. I know the FreeStyle ones are a little cheaper, though none of them are really all that reasonable. I went with a human meter because after paying for Rosa's diagnosis (2 lots of blood work and 3 vet visits) and her Lantus at $300, I couldn't afford the Alphatrak strips immediately! Fortunately, we did well with the ReliOn and I've since found that I was lucky and got one that reads really close to the lab values.
 
Wasted test strips the first 2 weeks means I had to use 1-3 strips per test.

When you use a human meter, do you use the number straight or do you convert to cat number?
 
When you use a human meter, do you use the number straight or do you convert to cat number?
You don't need to convert the number on a human meter, Kako.
But just bear in mind that pet-specific meters usually (but not always) read a tad higher than human meters.
The pet-specific meter numbers may be slightly closer to the test results your vet would get.

Eliz
 
We got Lantus and u-100 syringes, also 50 more test strips are arrived. ;)
Switch tomorrow morning be better than tonight, right? (I will stay up tonight if I need, though)
I am looking at Gizmo's SS. Start with 1 unit, test mainly +7 be suitable for Tux also?
 
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Yes, if you have the choice, making changes on the AM cycle so you don't have to stay up all night and test is preferable. :) Lantus initial dosing is based on the cat's weight - if they're at their ideal weight or above it, then it's based on their ideal weight. If he's underweight, then it would be based on his actual weight. Can you let us know how much Tux weighs at the moment and how much he ought to weigh?
 
10.6 isn't so far off average for a cat so I think it would be reasonable to assume that he's close to his ideal, unless he happens to be a very small cat and obviously overweight. That equates to 4.8 kg and the starting dose is 0.25 u per kg. That calculation actually gives you 1.2 u as a starting point, but I think it would be reasonable to round down to 1 u and see how he responds to that initially. :)
 
In that case I'd definitely round the dose down to 1 unit...that allows for him to be a little over his ideal weight right now. Does that sound reasonable to you, Mogs?
 
In that case I'd definitely round the dose down to 1 unit...that allows for him to be a little over his ideal weight right now. Does that sound reasonable to you, Mogs?
We will start with 1 unit, and we will shoot for ideal weight too. :)
About testing. Since Tux got ideal BG curve with Vetsulin, preshot and +7 be enough? Is +7 most likely the lowest time for Lantus?
 
The instructions for Lantus say that most cats hit their low point between +5 and +7. However, it does vary a lot. Rosa's lowest point was anywhere between +2 and +11 and moved pretty much on a daily basis. It was earlier if she was going to drop low and tended to be later if she was just 'surfing' in good numbers. What we usually ask people to do is get a pre-shot, a +2 and a mid-cycle (around +6) test during the daytime cycle to begin with. And then a pre-shot, +2 and before bed test at night. At least until we know how a cat is going to react to Lantus those are good starting points.
 
The instructions for Lantus say that most cats hit their low point between +5 and +7. However, it does vary a lot. Rosa's lowest point was anywhere between +2 and +11 and moved pretty much on a daily basis. It was earlier if she was going to drop low and tended to be later if she was just 'surfing' in good numbers. What we usually ask people to do is get a pre-shot, a +2 and a mid-cycle (around +6) test during the daytime cycle to begin with. And then a pre-shot, +2 and before bed test at night. At least until we know how a cat is going to react to Lantus those are good starting points.[/QUOT
OK, I will do so. Thank you and good night! :)
 
Good morning! Tux weights 10.4 lbs this morning and Pre-shot is 440. BG is going down!! I feel Tux can do well with Vetsulin. Moment of hesitation to make switch.
 
Hi Kako,

Having been through it myself, I know that it's a bit scary changing insulins but I am hoping that Tux will respond even better to his Lantus treatment. :)

The "no food for 2 hours before testing" rule stays with Lantus?
Yes; you need to lift food for two hours before the preshot tests. When getting the mid-cycle tests, you just decide on your feeding schedule and do spot-checks between doses. Typically Lantus nadirs are around the +5 to +7 mark but it depends on the individual cat's response and the nadir can move around a bit. As you build up data in Tux's spreadsheet it will help you to determine when the best times for testing will be.


Mogs
.
 
Morning, Kako! :)

Hang in there; you'll get into the rhythm of things fairly quickly. When I switched Saoirse from Vetsulin to Lantus it was so encouraging to see her numbers level out instead of seeing the massive see-saw every day. I hope Tux will have a similar good response. When the big swings in BG levels stop it may help Tux to feel a lot better, too (fingers and paws crossed).

:bighug:


Mogs
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Moment of hesitation to make switch.
As Mogs said, Kako, it can be a bit scary changing to a different insulin. (I've done it twice, and was scared both times....:nailbiting:...but was also sort of excited at the same time....:smuggrin: )

Take heart. You will very soon get the feel for how the new insulin is going to work in Tux's body.
And hopefully the Lantus will bring Tux into a much better range of numbers soon.
This should be a really positive step forwards in Tux's diabetes journey. :bighug:


Eliz
 
Pre-shot was 440. +2 is 460. ????? Maybe the insulin didn't go into Tux? The needle is shorter than u-40's, so maybe I didn't do right.
 
Pre-shot was 440. +2 is 460. ????? Maybe the insulin didn't go into Tux? The needle is shorter than u-40's, so maybe I didn't do right.
With meter variance those numbers are pretty much equal. That's fairly normal for a +2 on Lantus (unless it's a particularly active cycle).

NB: because Lantus is a depot insulin it takes a little while to 'fill up the tank' - typically 6-10 cycles (3-5 days) - before you can see how well a dose is working.

You can learn lots about Lantus and how it works by reading the stickies at the top of the following page:

http://www.felinediabetes.com/FDMB/forums/lantus-glargine-levemir-detemir.9/


Mogs
.
 
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Pre-shot was 440. +2 is 460. ????? Maybe the insulin didn't go into Tux? The needle is shorter than u-40's, so maybe I didn't do right.
Don't worry, Kako.
This is just the first Lantus shot. And Lantus works differently to Caninsulin.
Caninsulin is what we call an 'in and out' insulin. It acts pretty quickly and is usually out of the system 12 hours later.
Lantus is a 'depot' insulin. It builds a little store ('depot') of insulin in the body, and then that insulin is slowly released over time. It takes a little while (few days maybe) for that store to build up, and so it takes a little while to see the full effect of any dose of insulin.

Edited to add:
Here's the link to the Lantus forum, Kako. You may find it helpful to read through some of the 'stickies' at the top of this page. There's a lot of info there about how Lantus works. But DO ask as many questions as you want to also. There are many Lantus users here at FDMB.
http://www.felinediabetes.com/FDMB/forums/lantus-glargine-levemir-detemir.9/

Eliz
 
This morning I gently rolled the Lantus bottle to mix, pulled 2 units into the syringe and returned 1 unit back into the bottle, the way I was treating Vetsulin.
Oh No! Lantus is different from Vetsulin! Glad to find this soon.
 
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This morning I pulled 2 units into syringe and returned 1 unit back to the bottle. Oh No!
No need to panic. You only did that once so, while it's possible that it might reduce the life of the Lantus ever so slightly, it won't have done any real harm.
 
The instructions for Lantus say that most cats hit their low point between +5 and +7. However, it does vary a lot. Rosa's lowest point was anywhere between +2 and +11 and moved pretty much on a daily basis. It was earlier if she was going to drop low and tended to be later if she was just 'surfing' in good numbers. What we usually ask people to do is get a pre-shot, a +2 and a mid-cycle (around +6) test during the daytime cycle to begin with. And then a pre-shot, +2 and before bed test at night. At least until we know how a cat is going to react to Lantus those are good starting points.
I am looking at Rosa's SS. It has totally different colors from Tux's and it's pretty! I at first thought you were using different spreadsheet. :woot:
How did you install those horizontal lines where say BEGIN OTJ TRIAL and START OTJ TRIAL..... ?
 
I am looking at Rosa's SS. It has totally different colors from Tux's and it's pretty! I at first thought you were using different spreadsheet. :woot:
She got to pretty numbers in the end, but if you look at the first week or so there was nothing pretty about that at all! Her reading on diagnosis was 680 and I really never thought it would be possible for her to reach remission from such a high starting point. But she did, and so far (anti-jinx) she's been diet controlled for a little over a year now. So never give up hope! :)

How did you install those horizontal lines where say BEGIN OTJ TRIAL and START OTJ TRIAL..... ?
I selected the row I wanted to put the OTJ trial header on and merged the cells in the row so that all the boxes in that row turn into one big box. Then I typed in the information I wanted and used the 'horizontal align' button at the top of the spreadsheet to center the writing. Finally, because I wanted a different color for those rows than anything I was using anywhere else, I selected the row and used the 'fill' button (the one that looks like a paint can) to make the row a different color from everything else.
 
She got to pretty numbers in the end, but if you look at the first week or so there was nothing pretty about that at all! Her reading on diagnosis was 680 and I really never thought it would be possible for her to reach remission from such a high starting point. But she did, and so far (anti-jinx) she's been diet controlled for a little over a year now. So never give up hope! :)


I selected the row I wanted to put the OTJ trial header on and merged the cells in the row so that all the boxes in that row turn into one big box. Then I typed in the information I wanted and used the 'horizontal align' button at the top of the spreadsheet to center the writing. Finally, because I wanted a different color for those rows than anything I was using anywhere else, I selected the row and used the 'fill' button (the one that looks like a paint can) to make the row a different color from everything else.
Rosa's numbers came down so quickly. Took her only 10 days!?
I am tired of seeing blacks and reds so I added a pleasant color on Tux's SS. Thank you for explaining! :cat:
 
Tux will get there - remember Rosa was only ever given Lantus so we didn't have to go through switching insulins and re-starting the dose. Give him time - the first 5 days are tough because that's when the Lantus depot is building so you don't always see much change in the numbers then. But once you hit the right dose, he'll start giving you pretty numbers too! :) I like what you've done with your SS - it will make it really easy for us all to see the change in insulin when we're looking at his numbers. :)
 
Good morning ladies! AMPS 300! ;) Love the number, but I don't know how much Lantus to give him. 1 unit be good? Or it's too much?
 
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Tux will get there - remember Rosa was only ever given Lantus so we didn't have to go through switching insulins and re-starting the dose. Give him time - the first 5 days are tough because that's when the Lantus depot is building so you don't always see much change in the numbers then. But once you hit the right dose, he'll start giving you pretty numbers too! :) I like what you've done with your SS - it will make it really easy for us all to see the change in insulin when we're looking at his numbers. :)
What you did for Rosa is amazing! :rb_icon:
You went thru very very detailed adjustments up and down, and ended with 0.05 unit.
I am excited to see 300 AMPS today! But same time I am nervous deciding dose. Maybe I will be in panic when I see the first green!
How much dose you'd have given this morning, and how much dose you'd give tonight in case PMPS is in pink, yellow, or blue?  
 
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What you did for Rosa is amazing! :rb_icon:
Thank you! But Rosa did the really hard work - she had to heal herself! I just gave her the insulin. :)

You went thru very very detailed adjustments up and down, and ended with 0.05 unit.
That's what we usually do with Lantus - the smaller the dose we can finish up with, giving a cat support for as long as we can, the better chance we have of a strong remission.

I am excited to see 300 AMPS today! But same time I am nervous deciding dose. Maybe I will be in panic when I see the first green!
How much dose you'd have given this morning, and how much dose you'd give tonight in case PMPS is in pink, yellow, or blue?  
That's a great pre-shot number this morning! I like that. :) And yes, it's always a little bit scary when you see your first green number but there are people here to help you through being scared. Lantus isn't usually dosed on a sliding scale - we stick with a particular dose until the depot is full or until the cat earns a reduction. Dosing isn't based on the pre-shot number with Lantus - the reason we get a pre-shot number is to make sure that Tux is high enough for it to be safe for him to have a shot at all and because that and the +2 can often give you an early warning if Tux is likely to have a very active cycle. So based on that, I would have stuck with the 1 unit this morning. However, 0.75 if you weren't sure is fine - it's much better to reduce slightly if you're not sure than to skip the shot completely. If Tux is under 200 at any of his pre-shots for now, please post for advice - if there's a strong chance he will drop low, someone will stay with you to help you if he does get low enough to earn a reduction. And for anything over 200, we would usually give the full dose. As you get more used to Tux's response to the insulin, that pre-shot limit can be reduced - most people here will give a full dose for any number above 50 on a human meter or 68 on an Alphatrak - I think the lowest pre-shot number I gave a full dose on was around 56 or 57. Lantus is an insulin that does better at keeping numbers down than at dragging high numbers down and because it is gentler on a cat's system than Caninsulin, what we often find is that if the cat starts off in a lower number, they are likely to have a fairly flat cycle where the numbers don't move very much at all. That is actually very good for the cat because if they can spend all day in the normal range, then they are spending all that time healing.
 
Hi Kako,

I am positively delighted to see that Tux is responding so well to his Lantus! (Anti-jinx!) :cat: Much better than the blacks and reds.


Mogs
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Tux's numbers look GREAT Kako!! :) And you have a lot of people right here ready to help you when he decides to try the green range out for the first time! :bighug:
 
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