Thank you for the reply. Nero is doing better now. I gave him 2 days of mirtazapine (they said give 1/4 of the 15 mg tablet) - I dont know how I would reduce the tablet more - and he started to eat again and seemed to get better over the next few days. In the future, if this happens again, I will try the zofran for nausea, as you said. I was surprised when the vet said it is not absorbed by cats as I had read about it being used here. I only have 4 mg tablets however. I do not know the root cause of Nero having these episodes, I can only think he is getting some virus or bug or maybe it is pancreatitis. It seems like he is almost going to die and then he recovers - and is back to his former self. I think the fluids are vital and also the appetite stim did help but I understand what you are saying. Thank you for the info on gabapentin, I have that to use in the future if needed.