Tableau diagnosed with Pancreatitis - advice requested

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ehsuan

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Hello all you wonderful, kitty-caring people in FDMB. I know you know how incredible you all are for the support and knowledge and hand-holding you provide, and for caring for your wonderful kitties.

Writing with an update for Tableau. I'd like to say that things are improved, but unfortunately, they are not.

Tableau spent THursday and Friday in the hospital on IV fluids and electrolytes and perked up amazingly. So much so that this 16 year old cat was batting around cotton balls and swatting flies. He at like a little piggy, and when I got him home Friday night, he ate and ate and ate.

He was diagnosed with Pacreatitis . His fPL results were >50!!! WHich as some of you may know, is extraordinarily high. Additionally, his ALT was 647 (also extremely high). Kidney function is fine.

The vet sent us home with the following meds:

Metronidazole (50 mg 2x a day)
Ursodial (.3 mls 1 time a day)
Buprenex for pain 2-3 times a day
Cyproheptadine for appetite (1/2 tab once a day).

Additionally he is on 1 unit Lantus 2x day
1 ml amlodipine (high blood pressure)
cisipride for constipation
SUBQ FLUIDS

Wondering if anyone sees or suggests a different treatment plan or addition?

Unfortunately, since Saturday morning, he is back to not eating. He wants to eat but won't. Today he has been meowing so forlornly (and he's usually a quiet cat). We could put him back in the hospital, but even the vet thinks that it's a bandaid, and may not be worth putting him through anymore.

Basically he has so many uncontrolled health issues, that it seems insurmountable. He keeps getting worse and worse. His recent history (since April) is as follows:

Nasal carcinoma diagnosis (20 days of radiation)

Bortadella infection and ecoli in the nose. Those finally cleared up after three courses of antibiotic. But even with that cleared up, his nose is so compromised that he has chronic, significant, snuffy nose, so he can't smell and he has a lot of uncomfortable mucas in his throat.

He's had chronic constipation (although that's cleared up).

Uncontrolled diabetes since beginning of August.

Pancreatitis.

In the hospital they were able to control the diabetes with quick acting insulin and I wonder if that's why he was feeling so much better (in addition to the electrolytes).

He pretty much the last two days laying by the food bowls and staring at the wall. As I mentioned, he's also been meowing in what I assume is pain. He does get up and walk around, so he's able, but he doesn't really do anything (but that could be because of the pain medicine).

The last ditch effort she is suggesting is a course of prednisone. Again - last ditch effort. She says she's not recommending this lightly and that it may be the thing to get the inflamation under control so that we can then hopefully get the diabetes under control.

She doesn't, and I agree, want to do anything invasive (like a feeding tube) at this time. She feels he's too unstable. I forgot to mention he also has a heart murmur and asthma (controlled).

Anyway, I'm really looking for any advice or thoughts about all this. I know some of you have a lot of experience with so many feline issues. I also don't want him to needlessly suffer and it does seem like he is, for the first time, suffering.

THank you.
 
Pancreatitis is very painful, so the pain meds and fluids are important. He may also be a bit nauseated, and many of us give 1/4 of a 10 mg Pepcid AC. It really seems to help. You can give it twice a day. It might also help to split the Cyproheptadine into 1/4 twic a day - check with your vet. Do you have Fortiflora? If he looks like he is interested in his food disch, perhaps a little sprinkle of Forti would encourage him.
 
ehsuan said:
Unfortunately, since Saturday morning, he is back to not eating. He wants to eat but won't. Today he has been meowing so forlornly (and he's usually a quiet cat). We could put him back in the hospital, but even the vet thinks that it's a bandaid, and may not be worth putting him through anymore.

I am so sorry you and Tableau have joined the pancreatitis club, it is not a fun place to be, but the disease can be managed. It just takes a little trial and error to find out what treatments work best for each kitty. My Harley and I have been fighting the good fight against this since March. I'm impressed that your vet has nailed some of the key treatments right off the bat, she's a good one. :) I have two suggestions to offer to the list of meds. based on my experience with Harley. 1) The cyproheptadine dose seems rather high and it's usually dosed twice a day instead of once a day. I'd suggest splitting the dose in half and give 1/4 BID or quite frankly. giving only 1/8 BID. Cypro. can make cats rather yowly and agitated or it can make the lethargic. Harley got agitated on only 1/4 pill, ate fast and vomited. 1/8 pill worked much better with fewer side effects. Finding the right dose for each cat is kind of an ECID thing. 2) You also mentioned that he acts like he wants to eat but doesn't. Pancreatitis is very nauseating and if Tableau is as sick as Harley was, Pepcid will not be able to address severe nausea. Pepcid works best for nausea caused by too much stomach acid, not for nausea due to severe pain. The two best anti-nausea meds. for severe nausea are Zofram (ondansetron) and Anzemet (dolastetron). Both are human chemotherapy meds. The only cavaet to them both is that they were withdrawn from the human market because of safety concerns in people with pre-existing heart conditions. I do not know if this also applies to cats so you might want to discuss the risks versus rewards with your vet. I've been using Anzemet with Harley successfully since April of this year even though he has an abnormal heart rhythm.

Hope this helps and that Tableau is feeling much better soon.

:YMHUG: :YMHUG: to you and cat_pet_icon cat_pet_icon to your fur-baby.
 
Thanks Laura and "Just-as-appy" for your advice. I hadn't even considered nausea cause he hasn't thrown up, but I will talk to my vet first thing tomorrow. Someone else on my lantus board mentioned it is well. I'm glad to hear my vet did a good job with her scrips! I haven't been seeing her for very long (a couple of months) but she seems very good and extremely thorough.

I did give him some pepcid this afternoon and it did seem to help a little. He lapped up some baby food and ate a couple bites of regular food. He's still hovering by the food dish, so I hope he will eat some more.

I don't have fortiflora but will get some and try it. I will also try splitting the dose of the cypro.

So have your kitties been able to be "in remission" from the pancreatitis? Does it ebb and flow or have they actively had it for a while? Has the diabetes been able to be managed? I'm so afraid we will never get this stuff under control so that it's all manageable.

Tableau has been intermittently swatting at flies this afternoon, so he definitely seems to have some "oomph" left. I just want him to feel bette soon!

Thank you again for your help!
 
I just want to offer some hugs to you Emily, and am sending strong feel much better vines to Tableau.
 
Pancreatitis is quite painful, so you need pain meds. Tell your vet that you want buprenex.
Nausea is a big part, so get a box of Pepcid AC regular strength 10mg tabs. Max dose per day for cats is 5mg, so cut each tab into 1/4s, and give twice a day.
Fluids are needed most definitely. Tell your vet you want a fluids kit and if you don't know how to give fluids, don't worry. There are tons of people here on this site who can help you and you can also watch dozens of videos on Youtube. Have your vet get the vet tech to show you what needs to be done as well. The kits mostly are made up to include big needles size 18ga and some cats do not like them, so ask for some 22ga or even 20ga are OK. The fluids will enter slower but it won't be as uncomfortable for your cat.

I have two cats that have pancreatitis issues. Ollie is not so bad but Shadoe has always had big issues.
For the longest time, I gave her pepcid with her am and pm shots, sort of like a maint plan, and it did help her somewhat. I also add lots of water to her wet food and make it like a thick soup; it gets moisture in her.

I have since been giving Shadoe and Ollie B12 shots, as our vet stated it would help. Sure enough, I have not had to give Shadoe any pepcid and she has not had a single pancreatitis attack since starting her shots, given at home, in almost 2 months.

So, to treat pancreatitis you need 3 things: pepcid for nausea, buprenex or some pain med for the pain, and fluids for hydration.
 
ehsuan said:
Thanks Laura and "Just-as-appy" for your advice. I hadn't even considered nausea cause he hasn't thrown up, but I will talk to my vet first thing tomorrow. Someone else on my lantus board mentioned it is well. I'm glad to hear my vet did a good job with her scrips! I haven't been seeing her for very long (a couple of months) but she seems very good and extremely thorough.

I did give him some pepcid this afternoon and it did seem to help a little. He lapped up some baby food and ate a couple bites of regular food. He's still hovering by the food dish, so I hope he will eat some more.

I don't have fortiflora but will get some and try it. I will also try splitting the dose of the cypro.

So have your kitties been able to be "in remission" from the pancreatitis? Does it ebb and flow or have they actively had it for a while? Has the diabetes been able to be managed? I'm so afraid we will never get this stuff under control so that it's all manageable.

Tableau has been intermittently swatting at flies this afternoon, so he definitely seems to have some "oomph" left. I just want him to feel bette soon!

Thank you again for your help!

Hi Emily,

I'm glad to hear Tableau is feeling better since the Pepcid and at least ate something. Please talk to your vet about the stronger anti-nausea meds. as it is a common misconception even among the best of vets that if a kitty is not vomiting they are not nauseous and that is not so. Cats are very good at hiding pain (as we well know) and the signs of nausea are often very subtile. Refusing food completely, eating one kind of food and then the next meal, refusing to eat that food at all (it's as though they "blame" that food for making them feel sick and so they avoid it) showing signs of hunger and wanting to eat and then sniffing the food and walking away from the food bowl, or sniffing the food, licking the lips and walking away are all signs of nausea in cats. When Harley was most severely sick he wouldn't even drink water because he felt so bad.

It's hard to predict the course pancreatitis will take in each cat. Harley's attack was acute when we discovered it and we had to resort to using prednisolone and even a plasma transfusion to control the inflamation and we have not been able to wean Harley off the pred. without triggering another attack. He's currently on 5 mg SID. While his spec-fPL has come down from a high of 40 to surfing the 4's, he still has simmering pancreatitis and could flare at any time. I don't want to paint a picture of doom and gloom for you because Harley also has IBD which complicates things so he may be a more complicated case than Tableau may be. I see you've joined the Yahoo Feline Pancreatitis Support Group which is a phenominal resource. You'll get some great advice and help there.

Did your vet suggest doing any test for IBD? It would be a GI panel which would test for cobalamin (vitamin B-12), folate and TLI in addition to the spec-fPL. It's not necessary, but might be worth considering if Tableau does not respond to the current treatment. The metronidazole (Flagly) is commonly prescribed for IBD though so it looks like your vet has you covered there even without a formal diagnosis.

Regarding the diabetes management, we went from needing 0.2u of PZI to 2.5u of Levemir but that's because prednisolone causes insulin resistance. Of greater concern than the effect of pred. on BGs is that Tableau has a heart murmur. From what little I know, steroids are tricky business with heart kitties so while the diabetes and the insulin could be worked around the steroids, you'd want to discuss the pros and cons of using pred. with his heart condition if it ever comes down to needing to use it. Cross paws antijinx that you don't need to go down that road!

It sounds like Tableau is feeling better and I hope that continues!
 
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