I feel like I do a good job of making it as comfortable as possible-warming insulin vile in my hands, getting a good tent while she's eating, bevil side up on the needle, staying calm, etc. but it really just seems to hurt her.
Make sure you're grabbing enough loose skin to make a tent shape, pull it up tautly, feel for the depression that is the "tent door" and insert the needle near the bottom of the door but not too close to kitty. Sometimes a very slight downward angle helps. If you're using the scruff you could try loose skin along her sides. Skin tightness and clear impression of a tent door are key.
So what syringes do you all use and where do you buy them? Is the insulin conversion easy enough that it's worth switching?
Using U100 syringes with half unit marks and the conversion chart allows a bigger range of fractional doses. Here's a link to the conversion chart:
http://www.felinediabetes.com/insulin-conversions.htm
Here's an example of the U100 syringes you can use:
https://www.adwdiabetes.com/product/6941/bd-ultra-fine-insulin-syringes Walmart should have similar in their ReliOn store brand.
Re dose: you got a better response at 2 u but it'll be helpful to see data on a spreadsheet. Congrats on testing BG at home though!
Here's the new member's handout I made up a while ago:
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It would help us if you set up your signature (light grey text under a post). Here's how:
- click on your name in the upper right corner of this page
- click on "signature" in the men that drops down
- type the following in the box that opens: kitty's name/age/date of diabetes diagnosis/insulin you're using /glucose meter you're using/what he eats/any other meds or health issues he has.
Another thing that will help us help you now that you've started BG testing at home is to set up a spreadsheet like the one we use here. We can all see it and look at it before offering advice:
http://www.felinediabetes.com/FDMB/threads/fdmb-spreadsheet-instructions.130337/
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Here's the basic testing routine we recommend:
- test every day AM and PM before feeding and injecting (no food at least 2 hours before) to see if the planned dose is safe
- test at least once near mid cycle or at bedtime daily to see how low the BG goes
- do extra tests on days off to fill in the response picture
- if indicated by consistently high numbers on your spreadsheet, increase the dose by no more than 0.25 u at a time so you don't accidentally go right past a good dose
- post here for advice whenever you're confused or unsure of what to do.
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Here's an explanation of what we call "bouncing". It explains why a kitty's BG can go from low to sky high:
- BG goes low OR lower than usual OR drops too quickly.
- Kitty's body panics and thinks there's danger (OMG! My BG is too low!).
- Complex physiologic processes take glycogen stored in the liver (I think of it as "bounce fuel"), convert it to glucose and dump it into the bloodstream to counteract the perceived dangerously low BG.
- These processes go into overdrive in kitties who are bounce prone and keep the BG propped up varying lengths of time (AKA bouncing).
- Bounce prone kitty repeats this until his body learns that healthy low numbers are safe. Some kitties are slow learners.
- Too high a dose of insulin can keep them bouncing over and over until the " bounce fuel" runs out and they crash - ie., have a hypo episode. That's why we worry so much about kitties that have had too high a starting dose prescribed by the vet and the owner isn't home testing.
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Here are some tips on how to do urine ketone testing (VERY important if BG is high and kitty isn't eating well!):
- put the end of the test strip right in his urine stream as he's peeing
- slip a shallow, long handled spoon under his backside to catch a little pee - you don't need much
- put a double layer of plastic wrap over his favourite part of the litter box and poke some depressions in it too catch pee.
Most test strips have to be dipped and allowed to develop for 15 seconds before viewing the colour change in very good light.
I'm going to order the U-100 syringes that Kris suggested and hopefully the smaller needles will be more comfortable. 
I think it's time to try 2.25 u with Tessie. Hold that dose for two or three days and if you don't get any good blues at least, increase to 2.5 u after that. Keep posting here for advice.