So much water drinking, continued...

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susang

Member Since 2015
I'm re-posting this from the Intro section, at the suggestion of Karen:
Our cat is on Lantus 3U, the dose was raised from 2U a week ago. He is still not regulating, readings still in the 500's. It all started with an attack of Pancreatitis, out of the blue a month ago.

These high readings and all the drinking and peeing is so hard to see him go through. He's awake all night from all the back and forth to the water and litter box. He's drinking a cup of water overnight, this is what we took him to the emergency vet for to begin with.

Our goal of course after bringing him home from the emergency vet was to get to remission within a few months but so far we can't get him regulated.

He is so weak, his back legs with less strength. He used to run and play just a month ago. How is this damaging him, the high BS? And the strength in his back legs, his internal organs? How long to allow this to go on with the high BG? Someone suggested that maybe his BP is that high due to the stress of being at the vet. Who/how to help deal with ALL this?
 
Good morning, at least for a few more minutes where I am!
You can do this, it just takes a bit of time to get everything organized.

How about picking up Neosporin ointment with pain relief, an inexpensive meter, test strips, and alternate site testing lancets (a bit bigger needle to improve getting the blood drop) for today? The WalMart ReliOn Confirm works nicely if there's a WalMart near you, or the Target Up and Up meter.

Once you have that, read over the instructions for the meter and practice on yourself and/or a piece of fruit to get a feel for how it all works and the movements required.
 
Not home testing yet. Planning to but this has been overwhelming day and night. Got Keto-diastix. We were back at the emergency today. Changing from Lantus to PZI as internal med doc didn't think he's responding properly to Lantus. Is it ever possible to have remission from PZI? I so wanted him to respond to the Lantus for that reason. Thanks everyone for your concern, support, help!!
 
Lantus is a depot insulin and it takes 3-5 days to stabilize on a new dose. PZI is an in and out insulin, with no carry over effects.

It is possible to get off insulin with either, but not guaranteed.
 
Hi BJ, can you explain "depot" and "in and out" as far as these insulins go? Don't know if it was the insulin or something else but he just wasn't regulating so the new internal med doc though we should probably change to the PZI. There were periods of 3-5 days on the same dose over the month but he was not stabilizing. I sure wish we were one of those who just took to it without all these other problems. So hard to know what's happening with so many variables.
 
Sure.

Depot - when you inject Lantus, it forms small crystals under the skin. These slowly dissolve to release the insulin. There are some crystals left by the time of the next shot, so there are overlapping amounts of insulin being released. This is called the depot or shed. Dose adjustments are based on the nadir, the lowest glucose post shot. The cat does not have to eat before getting the shot because of the gradual effects of the insulin.

In and out insulins do not crystallize, nor bind to any proteins in the blood (which Levemir does) so their effects are more direct. They come in, drop the glucose, wear off, and are gone. No overlap between the shots unless you dose them closer together than the duration in the cat. Vets were most often trained in using the in and out insulins such as ProZinc, PZI, Caninsulin/Vetsulin (lasts 8-10 hours in the cat), or Humulin/Novolin NPH (lasts 6-8 hours in the cat).

Have you got any test data you can share with numbers and when they were taken with respect to the shot? Those help guide dose adjustments.
 
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