Side Effects With Onisor?

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Cat Ma

Cat Ma

Member Since 2015
Has any cats had side effects from Onisor? CJ vomited last night's meal today. She's had soft stools since being on Onisor for 3 days following her dental and a little diarrhea today. I gave her her last dose of Onisor last night. The vet doesn't think the Onisor would be causing stomach upset and diarrhea but these are listed as common side effects with Onisor.
 
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It is a non-steroidal anti-inflammatory drug (NSAID). Those may upset a GI tract, so give after eating, not before.
 
Sounds like some cats are affected by it while others aren't. If CJ needs a dental again, I wonder what alternative there is to Onisor that won't upset her stomach.
 
She's still on pred, right? I wonder if she could skip taking an anti-inflammatory next time since the pred is already fighting any inflammation she may have.

The digestive enzymes might help if she continues to have soft stools or diarrhea, but hopefully after the Onisor is out of her system, things will go back to normal. Feel better, CJ!
 
@Bobbie And Bubba Yes, I've been giving her some Forti Flora. Stools seem better tonight. She perked up with some pedialyte. I don't know if it's a side effect of Onisor but she is still gulping a lot of water since her dental and the first thought was her BG #'s went up again but they've been fine. So I sure hope her kidneys haven't been affected.

@granadilla I was instructed by the vet to continue the pred while she was on Onisor. I am going to ask the vet tomorrow, when CJ is brought in, if the Onisor was safe to give given her other issues and pred.

I am glad I held off Bonnie's dental till I get answers for her, too.
 
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Cat Ma said:
@Bobbie And Bubba Yes, I've been giving her some Forti Flora. Stools seem better tonight. She perked up with some pedialyte. I don't know if it's a side effect of Onisor but she is still gulping a lot of water since her dental and the first thought was her BG #'s went up again but they've been fine. So I sure hope her kidneys haven't been affected.

@granadilla I was instructed by the vet to continue the pred while she was on Onisor. I am going to ask the vet tomorrow, when CJ is brought in, if the Onisor was safe to give given her other issues and pred.

I am glad I held off Bonnie's dental till I get answers for her, too.
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Hopefully, the stools firm up. Shane had a good point about her all ready on the pred which is going to address any inflammation. Maybe the two were too much for her system? Sending "firm stool" vibes your way!
 
Cat Ma said:
Sounds like some cats are affected by it while others aren't. If CJ needs a dental again, I wonder what alternative there is to Onisor that won't upset her stomach.
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I think Aqua drops not sure of name but it's aqua something. I believe is some kind of amoxicillin. It's the only thing my cats can tolerate after dental care.
 
I saw you were already planning to ask the vet about this (and Shane mentioned it to), but looks like, in general, steroids shouldn't be simultaneously used with this med:
"should not be given with other nonsteroidal anti-inflammatory drugs (NSAIDs - i.e. aspirin, meloxicam) or corticosteroids (i.e. prednisone) or drugs potentially harmful to the kidneys."

Hope CJ feels better soon!
 
Still vomiting everything she's ever eaten since her dental. Stools are a little better. CJ was doing great till after the dental. Off to the vet.
 
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Thank you everyone. CJ and I appreciate the support, concerns and suggestions. CJ got a cerenia shot and pred shot today. I had to ask the vet to do injections so CJ wouldn't vomit up the meds. The vet said he wasn't familiar with Onisor or the potential side effects even though he prescribes it routinely after dentals. The vet had no idea there could be a potential risk/interaction with steroids, saying "there's not enough data yet because the drug is so new". :facepalm: He is convinced CJ reacted to the anesthesia, even though she's never reacted to it in the past, even with major surgery. And she's never had a bad experience with her prior dentals . He also thought her symptoms are because "she's partially diabetic" :banghead: even though her records clearly state she's in remission and includes all her BG logs. He did prescribe carafate to use if vomiting doesn't improve.

Sure glad I waited to do the dental with Bonnie so I can go over every detail beforehand. The dental is going to be with a different vet. There's no way Bonnie could hold up with what CJ has gone through. I wished I had argued more with the vet over not using Onisor but everyone there kept insisting it was "safe" to use. Maybe for most cats but clearly not for CJ.

It is hard for me to see this setback with CJ but hopefully she'll bounce back soon.
 
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Ah, sending healing vibes and vines! I think she will bounce back. At least now you know "why" it just has to get out of her system. We have to almost be Vets ourselves to protect our little ones. Guess we have to be good consumers and read all side effects and contraindications of all drugs RX to us and our fur babies. I know I will from now on because of what you are going through. These vets can't know everything unfortunately. It really does give new meaning to the word "practicing" medicine. Speedy recovery CJ!
 
What are the common side effects with Cerenia that cats here have experienced? CJ is meatloafing a bit and I wonder if that's from the Cerenia.
 
Ugh, I'm so sorry you and CJ are going through this. The first time I gave Marshmallow Cerenia, she seemed a bit lethargic. I told the vet and he said that wasn't common. When her nausea got really bad, I tried it again and it didn't seem to make her lethargic that time. I wouldn't think the Cerenia itself would cause meatloafing. Maybe she just doesn't feel good from the nausea and the vet visit. If her nausea comes back and the Carafate doesn't seem to help, you can give her both Cerenia and Ondansetron at the same time. That's what I did with Marshmallow. Plus Pepcid. Hopefully after some rest and absorbing all the meds in her system, she'll feel better. Poor CJ. Sending anti-nausea vines.

I'm also glad you waited to do Bonnie's dental!
 
woodsywife said:
The doctor doesn't know about onisar? He prescribes it routinely and doesn't know side effects? Makes me wonder.
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I have to agree, makes me wonder, a lot! After the disappointments with my last vet, I have reached the point where I ask about everything the vet plans to administer before he actually gives it. That way I hope I can avoid any issues. Why would a vet administer a drug he's not familiar with and doesn't know possible side effects of?!?

Poor CJ, I really hope she feels better soon! Sending more prayers and healing vines!
 
CJ was quite lethargic all day but perked up a bit tonight after I poked her. No nausea so far. BG # is a little high but still within normal limits. Think I am getting the diarrhea under control. Keep paws crossed.

Does anyone know how long a cerenia injection lasts?

The vet has been very good up till now with being cautious with what meds to give CJ and knowing how to treat her (aside from the diabetes). I erred in having too much faith in him this time, I guess.
 
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Cat Ma said:
This is an antibiotic, right? Would it be suitable for inflammation and pain?
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It is an antibiotic. They would get it twice a day for 7 days. I only give liquid meds to my cats. It's less stressful for them and me. For pain I would have to go back and read the info. I don't think I ever had a cat taking pain medicine. All my cats would get this after dental. Two of them had it for abscess they got from my nasty cat who would attack them. I have tried clavamox but every single one vomited and had diarrhea from it.
 
The vet has tried that antibiotic shot that lasts 2 weeks. But it never seemed to work so I won't even let them give it anymore.

I also had Smokey classified as medically exempt from rabies shot because of age and diabetes.
 
woodsywife said:
It is an antibiotic. They would get it twice a day for 7 days. I only give liquid meds to my cats. It's less stressful for them and me. For pain I would have to go back and read the info. I don't think I ever had a cat taking pain medicine. All my cats would get this after dental. Two of them had it for abscess they got from my nasty cat who would attack them. I have tried clavamox but every single one vomited and had diarrhea from it.
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From what I've read from your link, it doesn't appear to be a pain medication; it is an antibiotic. It depends on what is done during the dental; each cat is different. My cats react to clavamox too so they get amoxicillin when antibiotics are needed. Since CJ was vomiting, I asked for injections so she wouldn't vomit up her anti-nausea med. So far, the cerenia is working. I just wasn't expecting her to be lethargic. But better that than constant vomiting.
 
woodsywife said:
The vet has tried that antibiotic shot that lasts 2 weeks. But it never seemed to work so I won't even let them give it anymore.

I also had Smokey classified as medically exempt from rabies shot because of age and diabetes.
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My cats have done well with antibiotic shots. But, again, ECID (Each Cat is Different).
 
Cat Ma said:
From what I've read from your link, it doesn't appear to be a pain medication; it is an antibiotic. It depends on what is done during the dental; each cat is different. My cats react to clavamox too so they get amoxicillin when antibiotics are needed. Since CJ was vomiting, I asked for injections so she wouldn't vomit up her anti-nausea med. So far, the cerenia is working. I just wasn't expecting her to be lethargic. But better that than constant vomiting.
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I was always told they could be lethargic for 12 hrs after procedure due to anesthesia. 2 of my cats were lethargic till the following morning but they were done late in the day. One was for about 6 hrs. He was done very early in the morning. I always left them there til closing so the we're confined and more awake when I took them home. One had 7 teeth pulled. They gave her pain medication right before I picked her up and gave me enough to give for only 24 hrs. Every cat is different in how they react.
 
I adopted a cat a day after a leg was amputated. She was put back in the shelter (HK) without antibiotics or pain meds. She still had the needle catheter taped in her other leg. Afraid they would put her down I snatched her up. Immediately took to my vet. She was given meds but she vomited the clavamox. She wasn't eating, drinking and stopped using box. She was estimated to be 1 1/2 yrs. Only weighed 4 lbs. She was afraid of people. It was a long holiday weekend where I sat with her 24/7 confined in spare bedroom. Trying to spoon feed and keep her calm & comfortable. After 2 days she finally ate a piece of cheese. She would howl when something was wrong or when she wanted me awake. She was with us 14 yrs. She reacted to all meds so we did without whenever we could. Her thyroid was a problem. But found a pharmacy that customizes meds so we just had to find a flavor she liked. Guess what is was????? Cheese.
 
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Sorry for putting the story here. I was trying to get across ECID. With the rescue she was better off with no meds, pain, antibiotics etc. Never found anything she would keep down. We had no choice with the thyroid, she had to have that but again pills were vomited and plain liquid was vomited. The flavored could be mixed with her food and it stayed down. We found out 10 years later she had only 1 kidney. We don't know why or how.

So glad she is perking up. She will be herself in no time.
 
She hasn't been nauseous since her Cerenia shot. I am thinking she may now be constipated because she hasn't had a BM since the shot.
 
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Ah, hope she feels better ASAP. Will she let you rub her belly? My Sug, GA, had chronic constipation and when she got bad, I would massage her belly and where her intestines were to help move it. Often it would help.
ETA
 
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