I agree with Amy. Those were significantly low numbers yesterday, so i would definitely stick with the 3.5u until we can see what he gets to when he clears the bounce. In my opinion, you don't need to check hourly, but it does look like Rooh doesn't stay long in any lower range, except for last night.
Looking at yesterday, he went from 377 to 146 in 3 hours. Just dropping that quickly can cause a subsequent bounce. A cat doesn't have to get into low numbers to cause a bounce - it can also be from any range they aren't used to.
More on bouncing here.
Punkin had arthritis, which is a typical side-effect of acromegaly. Although many cats that don't have acro also have it. We used the adequan too - that seemed like it helped. You start out with frequent shots and gradually spread them out. We also gave him buprinorphin twice a day as a pain killer. We tried acupuncture with mixed results, although at first it seemed like it really helped, but he was so afraid of it i stopped the appointments.
Here is a reference to Somogyi from the
Tilly's Diabetes HomePage. This is the same protocol we follow but has some different wording. The section below is under "Increasing the Dose" the last paragraph:
Be aware that experimental studies in human diabetics over the last 15-20 have rejected the existence of the Somogyi effect (sometimes also called rebound). In cats, no studies have ever been done which properly demonstrate that such a phenomenon exists. Therefore, adjust the dose as described above, focusing on the nadir: don't do so-called rebound checks, as they only lead to unnecessary (and unhealthy!) hyperglycemia.
It's possible that your vet is referring to rebound, or what we call a bounce. It does look like Rooh is bouncing but that isn't very likely to resolve in the next 24 hours. Bounces can last up to 3 days. However, because Rooh didn't go up in dose per the protocol, starting at a fairly low dose and increasing in increments of 0.25u or 0.5u depending on the nadirs, there is still a possibility that he is overdosed.
If he were mine, I'd probably hold this dose for the next 3 days, test every 4 hours or so and see if there are some lower numbers in there, and see what happens in the next 3 days when he clears this bounce. He may clear it sooner, or he may take the whole 3 days from last night to clear it.