Refrigerate Insulin?

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CrookMom

Member Since 2018
Very new to all this, but I’m pretty sure my vet told me to keep the vial of insulin in the refrigerator, but today my husband looked at the packing insert and it said to keep it at room temperature once opened. So, should it be kept refrigerated or not? I don’t want it to ruin it by doing the wrong thing. It’s too expensive to let go bad. We are using Novolin-N (I’ve read on the forums that it’s not the best, but it’s what our vet prescribed). Please advise. Thanks
 
Well, the info post here says "Storage and shelf life: The different brands of NPH, Novolin N, and Humulin N may, on the package inserts, have slightly different instructions about storage and shelf life. So do refer to the package insert for information about your insulin." http://www.felinediabetes.com/FDMB/threads/beginners-guide-to-novolin-humulin-nph.186097/

And the data sheet about Novolin N (https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019959s073lbl.pdf) says:

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I have no experience with that type of insulin. Maybe someone who does will chime in. It is possible that while it is 'okay' to leave it at room temp, it may last longer refrigerated. That is the case with the Levemir pens.
 
You should store the insulin in the fridge. If you read the packing insert, it will tell you it's safe to leave out of the fridge for a period of 42 days and then any remaining should be discarded. Leaving it in the fridge will keep it from spoiling well beyond the manufacturer's suggested timeline (approx. 3-6 months depending on expiry on vial) which is important when dealing with the small doses our kitties need. Humans go through the vials much quicker so leaving it out of the fridge is really just for comfort sake of not injecting large amounts of cold insulin.
 
To maximize life, store the in-use vial in the fridge like one would store an unpunctured vial in the fridge. I have used without problems and with no noticeable decrease in efficity of N insulin that has been punctured for well over a year
 
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