Probable Diabetes, Sugars high, Vet appt, Levemir

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Hello,

My 17 yr old cat Bitsy has a history of Pancreatitis. The last major episode was Oct 2023 (throwing up lots, poor appetite). She had full senior panel done, sent home injectable Cerenia and Mirtazapine tabs, I gave her S/C fluids at home. Labwork confirmed Pancreatitis. After a few days she was fine. She began throwing up again in December so back to Vet. Labs showed Glucose was slightly elevated but thought to be likely due to stress. Because of her history of pancreatitis, I know that puts her more at risk for developing Diabetes (I used to be a regular in this group, years ago had a diabetic kitty x 6 years) so I would check her BG at home. Back in Dec or Jan one evening it was quite elevated at 333 and she seemed a little less bright, drinking more, peeing larger clumps. Took her back to Vet, showed him the readings I was getting at home (that were elevated). He believed that because the lab's glucose range, normal is up to 180, that home glucose meter readings of 10 or a bit over are "normal" also (which of course goes against everything I read about feline diabetes.....everything I read says normal home testing values are below 120. I had them run a Fructoasmine level which came back with her within the normal range. Over time her glucose at home was better/normal so I attributed the previous increases due to Pancreatitis again.

Fast forward to Oct 12/2024....she started throwing up again several times, not as bright, drinking more water, loose poops and I saw her straining in the litterbox then throwing up clear liquid in the litterbox right after straining. Was concerned about possible UTI. Saw a different Vet at same cliinic. Told him about her history of Pancreatitis. Had him do xray of abdomen and microscopic urinalysis. Xray fine. Urinalysis was totally normal, plus no glucose, no ketones, negative for everything. Sent home w/ injectable Cerenia and some Mirtazapine tablets (2mg), had one shot of Cerenia that evening and she was back to her usual self. Poops quite soft still so started adding FortiFlora to her canned food daily which helped.

On Oct 18th I decided to check her BG at home and since. To note, she gets canned food twice a day (she nibbles at it all day) and a bit of dry here and there (some kind of Purina Naturals....cheap crap but it's the only kind she likes).

Oct 18:
noon - 243
5:30pm - 252

Oct 19:
08:45am - 260
3:00pm - 234
(NOTE: this day I started her on Purina DM dry food from the Vet, for the odd time she nibbles dry in between her main meals of canned, as it's lower carb than the regular dry)

Oct 20:
07:00am - 270 (as she'd been drinking more, I decided to give her 50cc of S/C fluids)
noon - 156 (figure the s/c fluids that morning caused this improved BG)
7:00pm -187

Oct 21:
08:30am - 253
9:00pm - 189

Oct 22:
06:30am - 266
2:30pm - 176
9:00pm - 183

Oct 23:
8:30am - 122
10:30am - 162
9:30pm - 217

Oct 24:
09:15am -135
9:30pm - 183

Oct 25:
06:00am - 228

Oct 26:
07:00am - 208
7:00pm - 157

Oct 27:
7:00PM - 205

Oct 28:
09:00am - 228
7:30pm - 270 (NOTE: I decided to take away the Purina DM dry food, will feed only wet)
8:30pm - 274
11:30pm - 266

Oct 29:
09:00am - 248 (this was after not eating any low carb fancy feast pate since midnight)

I will no longer feed any dry food at all. I am trying to feed the low carb varieties of canned though she's fussy and loves her gravies and sauces (eg: Fancy Feast Florentine Tuna and Salmon). She is not the kind of cat to eat canned twice a day, she nibbles off and on all day.....which obviously doesn't really give her BG a chance to lower after meals because she's constantly eating/grazing.....but this is just the way she is and at 17 I don't think I can change that.

the Meter I use is a new One Touch Verio Reflect

As you can see from her above readings, they're not terribly high and some are much better than others....so I'm a little nervous about starting insulin. I do have a Vet appt at noon today. I don't see much value in doing another Fructoasmine level given that I've been monitoring her for the past 10 days or so. I'm sure he'll say "well when we did her Urinalysis on Oct 13 it showed no glucose or ketones but that was then, this is now.

She does have a very good appetite, which is common w/ diabetes. She's not drinking tons of water but enough that it's a little more. She had a full senior panel in March 2024 and kidneys perfect, everything perfect. In very good health for her age, given this Pancreatitis/?diabetes stuff. You can tell she's not quite feeling herself as she's not as active and that totally correlates with how high her BG is. No diarrhea, no vomiting.

Would you start insulin if you were me? I just have this feeling that Vet is going to say "her numbers aren't terrible" and that we should do nothing. I don't want to jump the gun should her elevated BGs be due to maybe some inflammation to the pancreas again but I don't think she's got Pancreatitis at this point as no vomiting and appetite is good and she always throws up a lot when has Pancreatitis.

My hope is to start her on a very low dose of insulin, like 1/2 a unit.....start low, go slow......because as you can see from some of her numbers above, some are pretty decent so I don't want to worry that insulin will drop her too low. My kitty years ago did wonderfully on Levemir insulin and even though I know that ECID, I like the way Levemir works......nice flat curve versus huge peak. What are your thoughts about my plan that I'll discuss with Vet? I don't know what I'll do, however, if he says he doesn't think we should start insulin yet.

I would greatly appreciate your input before we head off to the Vet in 45 minutes ,please and thank you

Lisa in Canada
 
Hello,

My 17 yr old cat Bitsy has a history of Pancreatitis. The last major episode was Oct 2023 (throwing up lots, poor appetite). She had full senior panel done, sent home injectable Cerenia and Mirtazapine tabs, I gave her S/C fluids at home. Labwork confirmed Pancreatitis. After a few days she was fine. She began throwing up again in December so back to Vet. Labs showed Glucose was slightly elevated but thought to be likely due to stress. Because of her history of pancreatitis, I know that puts her more at risk for developing Diabetes (I used to be a regular in this group, years ago had a diabetic kitty x 6 years) so I would check her BG at home. Back in Dec or Jan one evening it was quite elevated at 333 and she seemed a little less bright, drinking more, peeing larger clumps. Took her back to Vet, showed him the readings I was getting at home (that were elevated). He believed that because the lab's glucose range, normal is up to 180, that home glucose meter readings of 10 or a bit over are "normal" also (which of course goes against everything I read about feline diabetes.....everything I read says normal home testing values are below 120. I had them run a Fructoasmine level which came back with her within the normal range. Over time her glucose at home was better/normal so I attributed the previous increases due to Pancreatitis again.

Fast forward to Oct 12/2024....she started throwing up again several times, not as bright, drinking more water, loose poops and I saw her straining in the litterbox then throwing up clear liquid in the litterbox right after straining. Was concerned about possible UTI. Saw a different Vet at same cliinic. Told him about her history of Pancreatitis. Had him do xray of abdomen and microscopic urinalysis. Xray fine. Urinalysis was totally normal, plus no glucose, no ketones, negative for everything. Sent home w/ injectable Cerenia and some Mirtazapine tablets (2mg), had one shot of Cerenia that evening and she was back to her usual self. Poops quite soft still so started adding FortiFlora to her canned food daily which helped.

On Oct 18th I decided to check her BG at home and since. To note, she gets canned food twice a day (she nibbles at it all day) and a bit of dry here and there (some kind of Purina Naturals....cheap crap but it's the only kind she likes).

Oct 18:
noon - 243
5:30pm - 252

Oct 19:
08:45am - 260
3:00pm - 234
(NOTE: this day I started her on Purina DM dry food from the Vet, for the odd time she nibbles dry in between her main meals of canned, as it's lower carb than the regular dry)

Oct 20:
07:00am - 270 (as she'd been drinking more, I decided to give her 50cc of S/C fluids)
noon - 156 (figure the s/c fluids that morning caused this improved BG)
7:00pm -187

Oct 21:
08:30am - 253
9:00pm - 189

Oct 22:
06:30am - 266
2:30pm - 176
9:00pm - 183

Oct 23:
8:30am - 122
10:30am - 162
9:30pm - 217

Oct 24:
09:15am -135
9:30pm - 183

Oct 25:
06:00am - 228

Oct 26:
07:00am - 208
7:00pm - 157

Oct 27:
7:00PM - 205

Oct 28:
09:00am - 228
7:30pm - 270 (NOTE: I decided to take away the Purina DM dry food, will feed only wet)
8:30pm - 274
11:30pm - 266

Oct 29:
09:00am - 248 (this was after not eating any low carb fancy feast pate since midnight)

I will no longer feed any dry food at all. I am trying to feed the low carb varieties of canned though she's fussy and loves her gravies and sauces (eg: Fancy Feast Florentine Tuna and Salmon). She is not the kind of cat to eat canned twice a day, she nibbles off and on all day.....which obviously doesn't really give her BG a chance to lower after meals because she's constantly eating/grazing.....but this is just the way she is and at 17 I don't think I can change that.

the Meter I use is a new One Touch Verio Reflect

As you can see from her above readings, they're not terribly high and some are much better than others....so I'm a little nervous about starting insulin. I do have a Vet appt at noon today. I don't see much value in doing another Fructoasmine level given that I've been monitoring her for the past 10 days or so. I'm sure he'll say "well when we did her Urinalysis on Oct 13 it showed no glucose or ketones but that was then, this is now.

She does have a very good appetite, which is common w/ diabetes. She's not drinking tons of water but enough that it's a little more. She had a full senior panel in March 2024 and kidneys perfect, everything perfect. In very good health for her age, given this Pancreatitis/?diabetes stuff. You can tell she's not quite feeling herself as she's not as active and that totally correlates with how high her BG is. No diarrhea, no vomiting.

Would you start insulin if you were me? I just have this feeling that Vet is going to say "her numbers aren't terrible" and that we should do nothing. I don't want to jump the gun should her elevated BGs be due to maybe some inflammation to the pancreas again but I don't think she's got Pancreatitis at this point as no vomiting and appetite is good and she always throws up a lot when has Pancreatitis.

My hope is to start her on a very low dose of insulin, like 1/2 a unit.....start low, go slow......because as you can see from some of her numbers above, some are pretty decent so I don't want to worry that insulin will drop her too low. My kitty years ago did wonderfully on Levemir insulin and even though I know that ECID, I like the way Levemir works......nice flat curve versus huge peak. What are your thoughts about my plan that I'll discuss with Vet? I don't know what I'll do, however, if he says he doesn't think we should start insulin yet.

I would greatly appreciate your input before we head off to the Vet in 45 minutes ,please and thank you
Lisa in Canada
I tagged a couple of members that can put you in contact with someone from Canada, and they can also reach out about your concerns, you are in the right place as you already know, we are here for you:bighug::cat::cat:
@Bron and Sheba (GA)
@Sienne and Gabby (GA)
 
If it were me and the last labs were in March, I'd have labs run again -- both bloodwork and a urinalysis and ane sure to get a fructosamine test included.

I know that Levemir is being discontinued in the US. I don't know if that's the case in Canada. You may need to check with a local pharmacy.
 
UPDATE, BACK FROM THE VET APPOINTMENT. Well as I half expected, her reviewed her numbers I posted above and didn't feel it's conclusive enough to consider her diabetic and start her on insulin. He was very worried if we did at this point that her risk of going Hypo would be too great. She ate almost half a can of Friskies pate starting at 9am. At 12:30 I checked her BG there in the exam room with my meter and they used their meter to check from the same ear poke (they use AlphaTRAK3 monitor for pets).....I got 243 and they got 257. He suggested I get a full senior panel done but I told him that I didn't see the value in doing that, we already know her BG is elevated and the stress of the blood draw will raise it even more. He said that he wouldn't want to start her on insulin or consider her diabetic unless she shows glucose (or ketones) in her urine. So I had them do a cysto to obtain a sample and use a dipstick to test. He took a pic of the test strip to show me. the reagent pad wasn't quite green enough to be "trace" but it was a touch greener than the "negative" pad color. Ketones negative.

He said the trace Glucose could be due to stress but this makes no sense to me because even the stress of a car ride to Vet (she never says a peep, travels very well), being at the Vet and the stress of the Cysto being done isn't going to suddenly cause glucose to spill into her urine at that moment. He pulled up her Fructoasmine level result that was done back in March 2024 but that is of no value to me, (it was negative then), that was 7 months ago. Her Urinalysis done Oct 13/24 was negative for Gluc and Ketones but again, that was then, this is now. He suggested I buy a Freestyle Libre and then monitor her glucose for the next 2 weeks. I've read mixed reviews here about using that in a cat so I told him I'll save the money and just continue to monitor at home, she's super easy to test with my One Touch Verio Reflect meter. He told me to test regularly for the next 5-6 days then call him Sunday and let him know what her numbers have been. I guess depending what they are at that point, perhaps test urine again w/ dipstick for glucose and ketones?

How accurate is a urine dipstick for glucose and ketones? Would it have been more accurate to have had her urine sent off to the lab to test for glucose/ketones?

Her weight is not dropping, was 4.7 kg on Oct 13, today was 4.92

No diarrhea now, peeing is normal, appetite good, no vomiting.

I'll continue to just feed her the lowest carb canned food (the types without sauce/gravy).

Again....the lab they use shows normal blood glucose in cats as being 88 - 174 so overall he doesn't think she's terribly high but everything I read online says that normal glucose in a cat, 120 is the top end of normal range.

All I can do is keep testing at home for the next few days, hopefully she won't continue to climb. It was so much easier with my other cat who was diabetic years ago. He didn't have a history of pancreatitis and when he was diagnosed, he was SUPER HIGH so there was no question.
 
If it were me and the last labs were in March, I'd have labs run again -- both bloodwork and a urinalysis and ane sure to get a fructosamine test included.

I know that Levemir is being discontinued in the US. I don't know if that's the case in Canada. You may need to check with a local pharmacy.

Hello, thanks so much for your response. If money was no object I would have had them do a senior panel, u/a again and frucstosoamine level but those 3 would have been $550 including the exam fee today. I just spent $465 there on Oct 13. I've had so many unexpected emergencies come up over the past 2 weeks (my furnace, my dryer) and just finished depleting my savings totally from having to have $2000 worth of dental work done. I'm on disability so money is always tight. Ugh. Going to see if there are some things around my home I can sell on FB Marketplace to help. That's interesting about Levemir, I had read that it was discontinued in some countries. I had phoned the pharmacy today and they said they had it but I guess who knows how long for? In all honesty, I don't even know if the Vet would even agree to Levemir, am sure he's never heard of it, seems most Vets want to Caninsulin and don't know of other options, doubt he'd feel comfortable writing a Rx for an insulin he knows nothing about. Funny thing, too......here in Canada you can walk into any pharmacy and buy any type of insulin for humans without a Rx but I was told if it's for a pet, I need a Rx from the Vet. that makes no sense. It didn't used to be that way.
 
Yes, as someone living in Alberta too, unfortunately that’s been my experience although apparently not the same in other provinces where you can walk in and get insulin for a pet without a prescription. A prescription from my vet was required in order to get both Lantus which we started with and now Levemir, since insulin is categorized as requiring scripts in the standards for pharmacy practice in Alberta. Use of drugs and medications for humans in animals are considered extra label drug use and insulin falls in this category, so it requires a prescription from the vet.

FF Florentine tuna appears to be medium carb, approx 14% carb unless the formula/ingredients have changed. Looks like there is some function by the pancreas, so if it were me, I’d ditch the dry for sure, and find some canned foods less than 10% and see how that works.
 
Yes, as someone living in Alberta too, unfortunately that’s been my experience although apparently not the same in other provinces where you can walk in and get insulin for a pet without a prescription. A prescription from my vet was required in order to get both Lantus which we started with and now Levemir, since insulin is categorized as requiring scripts in the standards for pharmacy practice in Alberta. Use of drugs and medications for humans in animals are considered extra label drug use and insulin falls in this category, so it requires a prescription from the vet.

FF Florentine tuna appears to be medium carb, approx 14% carb unless the formula/ingredients have changed. Looks like there is some function by the pancreas, so if it were me, I’d ditch the dry for sure, and find some canned foods less than 10% and see how that works.

Hi Christie, which food chart did you find that on? All I have ever found was the realllllllllly old food chart from years ago, from Janet & Binky (think it was more for CRF kitties as it listed the phosphorus contents as well), I haven't found a more update one as I always consider that ingredients change over the years. I know the Fancy Feast pate are low carb and I bought a 24 pack of those but silly kitty, although most cats love FF pate, she's not crazy about it lol. Back when she had her bigger Pancreatitis flare a year ago, she became very very fussy about food. She wouldn't even eat the $100 a bag grain free dry food that she'd been on for years.....(just supplemented with that, she'd still get canned twice a day always). I was having to give her Mirtazapine often to stimulate her appetite. I was desperate then to get her to eat anything so I spent a literal fortune on every single kind of canned food out there. I would mostly order the really good quality stuff, $3-$4 a can (she was eating better than I was lol)....from Homesalive.ca. Over time I found what she liked the most was that Fancy Feast Florentine. I've figured it's higher in carbs because of the sauce it's in. The past week I've been feeding her Friskies Pate mostly, and stopped all dry (even the Prescription diabetic dry from the Vet).

I woke up at 3am and she was curled up by my feet so I decided to check her BG ...and to my huge surprise she was 129 (7.3)!!! This morning at 7:15am she was 166 (9.2) and she was very hungry so put out half a can of Friskies Pate for her which she was thrilled with. So yes, her pancreas obviously still is working, thank God, so starting insulin yesterday would have been the wrong move for sure. I'll just keep checking her BG 4 times a day for the next few days (more if she starts going up high) and see where we're at when I call Vet on Sunday to report her numbers.
 
Have you tried the Fancy Feast Pates they are low carb
Food chart
http://catinfo.org/docs/CatFoodProteinFatCarbPhosphorusChart.pdf

Thank you so much for that food chart. For some reason I never found it and over the years would always refer to the old one by Janet & Binky.

I've always remembered that the Fancy Feast Pates are low carb (it's what I used to feed my sugar kitty Taco years ago as he was diabetic), but strangely enough Bitsy is not a fan of these. She has always been more of a canned with sauce and gravy kind of girl lol. Her consistent fave is the Fancy Feast Florentine Tuna or Salmon which I knew is higher in carbs (food chart shows 14%). For the past few days she's been very agreeable to Friskies Salmon Pate (3%) or Ocean Whitefish & Tuna (4%). Am going to try to sneak some Fancy Feast Pate into the Friskies to see how she does with that?
 
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