? Numbers all over the place...any ideas as to why?

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Hshray

Member Since 2021
My cat is on vetsulin and his numbers are all over the place. We’ve been gradually increasing his dose. He is rarely in the blues and has never had a number in the green. Today we have him two units in the morning and it looked like his numbers were coming down nicely but they started going up again before his usual nadir. Any ideas as to why or suggestions as to what we can do to get him regulated?
 
I think you're doing fine on the increases, for one. Some kitties need a little more juice than others. What could have happened today was a bounce.

Bouncing is a phenomenon that occurs when the body experiences (or at least thinks it does) hypoglycemia. Luckily the body uses bouncing as a defense mechanism against this where it attempts to compensate the low blood sugar by dumping excess glucose in an attempt to raise blood sugar back to “normal” numbers. Unfortunately, “normal” is a relative term according to the body. For a diabetic whose body has been untreated for so long that it considered very high numbers to be the new normal, lower numbers can often make the body overreact in attempt to save itself, even if it’s not in danger.

A cat who has been suffering from diabetes for some time may at the point of diagnosis have a new “normal” of 400. When insulin is introduced and brings it down, even to 200 (still diabetic levels), the body thinks it is in danger, dumps excess glucose, and thus the blood sugar skyrockets up to the 400-600s. After enough time has passed, the body will eventually realize that 200 isn’t such a bad number, and bouncing will happen less often. Note some cats are extremely bounce-prone and a switch to Lantus/Levemir is needed.

There are three main causes of bouncing: when blood sugar drops too low (hypoglycemia), drops lower than the body is used too, or by dropping too much too quickly. Typically if a cat drops more than 50% of their blood sugar a bounce is likely to happen, or if they drop 100 points within an hour.

While bouncing can be considered as a safety net in the instances of hypoglycemia, it can look very confusing on paper.

Note the part in bold, I suspect this may have happened to George today. I think the other part that needs faced is that on Vetsulin, you're only going to get so far. It has a very short duration and due to it's fast action actually encourages bouncing in a lot of cats. I would switch to Lantus or Prozinc which are better designed for felines. If you look at my spreadsheet you can see where we were on Vetsulin and switched to Prozinc with immediate improvement, then with the switch to Lantus even more improvement. Lantus can be purchased from Marks Marine Pharmacy for a third of the cost, making it cheaper than Vetsulin in the long run.
 
I think you're doing fine on the increases, for one. Some kitties need a little more juice than others. What could have happened today was a bounce.



Note the part in bold, I suspect this may have happened to George today. I think the other part that needs faced is that on Vetsulin, you're only going to get so far. It has a very short duration and due to it's fast action actually encourages bouncing in a lot of cats. I would switch to Lantus or Prozinc which are better designed for felines. If you look at my spreadsheet you can see where we were on Vetsulin and switched to Prozinc with immediate improvement, then with the switch to Lantus even more improvement. Lantus can be purchased from Marks Marine Pharmacy for a third of the cost, making it cheaper than Vetsulin in the long run.

Thank you so much for the reply! This is very helpful and makes a lot of sense. It’s good to know what is considered a large drop and sounds like that’s probably what has happened with George a few times at least.

And I agree about the Vetsulin too. I will ask the vet about switching to Prozinc and hopefully that will help us get longer coverage and more consistency. I really appreciate the information you’ve provided!
 
I would encourage you to do some testing on the Pm cycles as cats often drop lower at night. At the moment you have no idea how low he could be dropping over night.
I favour Lantus myself. While there are people here who use Prozinc and can help, we have a lot more people who use Lantus.
 
I think you're doing fine on the increases, for one. Some kitties need a little more juice than others. What could have happened today was a bounce.



Note the part in bold, I suspect this may have happened to George today. I think the other part that needs faced is that on Vetsulin, you're only going to get so far. It has a very short duration and due to it's fast action actually encourages bouncing in a lot of cats. I would switch to Lantus or Prozinc which are better designed for felines. If you look at my spreadsheet you can see where we were on Vetsulin and switched to Prozinc with immediate improvement, then with the switch to Lantus even more improvement. Lantus can be purchased from Marks Marine Pharmacy for a third of the cost, making it cheaper than Vetsulin in the long run.
It looks like it may have happened again? really not good numbers today :(
 
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