After 10 cycles you see the nadirs and if they are still coming down or where you want them you hold a little longer. If not spending enough time in normal numbers you increase. You can refer to the sticky on TR. Ask for dosing advice again on day 5.
Hold the initial starting dose for 5 - 7 days (10 - 14 consecutive cycles) unless the numbers tell you otherwise. Kitties experiencing high flat curves or prone to ketones may want to increase the starting dose after 3 days (6 consecutive cycles).
Each subsequent dose is held for a minimum of 3 days (6 consecutive cycles) unless kitty earns a reduction (See: Reducing the dose...).
Adjustments to dose are based on nadirs with only some consideration given to preshot numbers.