Hi Lisa and Little! Welcome to the Prozinc forum! We're a small group, so sometimes it can take a bit to get an answer, but we all try to check in several times a day (I'm doing my afternoon check in now which is how I found your post!). Sharon has given you great info on desensitization. Her advice is spot on and I would encourage you to do that as often as you can at first. She'll start to see that spot as good (and all kitties love a good bribe...er...treat!). I even had special treats that were just for testing. It got to the point in my house that if I shook the lancet box, not just my diabetic but ALL cats would come running...I always had a audience at test time!
I see you're using an Alpha Trak meter. That's fine, but I would add it to your signature if you don't mind. We can read from both human and pet meters but the numbers are different so we have to be sure we know what we're talking about!
Okay as for dosing I do NOT recommend jumping to 2 units. Little really isn't in bad numbers, and a 1 unit jump is too much for our little cats. We usually go no more than 0.5 units at a time. With Little's numbers, I would recommend increasing only by 0.25 at a time for now. I know you're having trouble testing, but it would really help if you get get some test in at the +5 - +7 hours (that means 5 to 7 hours after the shot). That will help us know how low the insulin is taking Little, which is part of what we base dosing off of. Any chance you could get one test in that time frame?
I know hypo is scary, but Little seems to be in very good and safe numbers so far. 2 and a half hours after insulin this morning, she hadn't dropped too far. With the pet meter, 68 is what we call the take action number (this doesn't mean the cat is in hypo...it means that the cat COULD be going that way, so you want to take action to prevent it). With a number of 385, Little has over 200 points to drop before that...and that's a lot. It's not impossible, but it is less likely since most cats hit the lowest point of their cycle 5-7 hours after the shot (this isn't exact...some cats are different than that, but it's what we usually see). IF you ever have a hypo, post both here and in the Main forum so you can get as many eyes as possible. There's a 911 icon that you can use that will get your post pretty fast attention. There's almost always someone around on some forum, and we've walked people through hypos plenty of times.
Okay, I don't want to overwhelm you, so I'm going to stop here for now. Please let me know what questions you have! We are here to help and we know this is a steep learning curve...we want to be sure we are giving you whatever you need!