New insulin for Bob

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Lkldcatlady

Member Since 2013
Well, Bob is moving from prozinc to Lantus. Yay!! Just have a couple questions. Ill be giving him 2 units and I don't quite understand the u100 needle!! Am I only pulling insulin in up to the 2nd lolittle black line? It doesn't seem like very much. Also, I think I read Lantus last 18 hours. Does that mean the midpoint should be 7-9 hours?
 
Yes lantus is small small doses. It lasts 12hours in the system. Nadir is around the 6hour mark. Although every cat is different...

Wendy
 
Hard to tell since every cat is different,, but it will start working immediately. Just may take a few days to see optimal results.. And of course you need to find the right dose.
 
When switching insulins, one way to do so is to take 70% of your current insulin dose and start there.
Ie 0.7 * current dose = starting Lantus dose.

Unless he goes too low, keep the first dose level for 5 full days / 10 shots.

Good luck!
 
The dr actually started him at 2 units (70 % of his prozinc dose would be 3.5) but she expects to go up. I read on one of the stickys that u should not draw extra Lantus into the needle and then squirt back into the bottle (which is what I did with prozinc). It supposedly contaminates the insulin. Is that true? It was IMPOSSIBLE for me to get 2 units without a giant air bubble!!!! It was such a teeny tiny amount compared to the prozinc. I'm assuming its more powerful?
 
Take out a fresh insulin suyringe
Move the plunger up and down a couple of times to spread the lubricant in the barrel
Draw air into the syringe so that plunger is at the line of your dose
Inject the air into the vial, with vial right side up
Turn vial upside down so needle is pointed at the ceiling
Slowly and evenly, Draw out the insulin but do not squirt excess back into the vial
Overdraw the insulin by a little bit
Pull the needle out of the vial
Hold the needle pointed up towards the ceiling
Tap the side of the syringe to force the air bubbles to the top
Twist the plunger slowly to squirt out the excess insulin, into a tissue or the sink
You now have your correct insulin dose.

Are you using U-100, 3/10 cc insulin syringes with the 1/2 unit markings?

The 3/10cc is better for use with those small doses, the 1/2 unit's even more for when you change your dose by no more than 0.25U so you do not bypass the good dose for Bob.
 
Yikes! That's alot of steps!! But ill give it a try tonite. Thanks! I really hope this insulin works better with Bob. The prozinc really didn't do anything....
 
Oh, Ieant to say I don't think there are 1/2 unit marks. Ill have to look closer when I get home. But I only think I saw 4 marks between the beginning and the number 5
 
Lkldcatlady said:
Yikes! That's alot of steps!! But ill give it a try tonite. Thanks! I really hope this insulin works better with Bob. The prozinc really didn't do anything....
You were probably doing most if not all of these steps when you were using the prozinc. I just wanted to give them ALL to you again. ;-)

Maybe see if there was a step you were missing.
Maybe a tiny change in your technique would make a difference.

What syringes are you using? Some people dislike the BD syringes because they always have bubbles.
 
I was told by my regular vet to draw in tooth prozinc and shoot the rest back in the bottle so I never did all those steps. I'm using Terumo 29 gauge x 1/2" needles 1/2cc. All there are are 4 little marks and then a 5, 4 little marks, then a 10. No half units, right? I don't mean to sound stupid, I'm just amazed at how all the dose is compared to what he was getting with the prozinc and the u40 needle.
 
But you got new U-100 needles to use with the new lantus insulin right?

There are a wide range of insulin syringes you can get to use with insulin. You got the 1/2cc insulin syringes which only have 1U markings. there are also 1cc insulin syringes which have 2u markings. Then there are our recommended 3/10cc insulin syringes. These 3/10cc syringes are made for children. The marks are a teensy bit farther apart. These 3/10cc syringes are available with 1 unit markings and some have 1/2unit markings.

The 3/10cc syringes with the 1/2unit markings are easier to use with smaller doses, especially when you are measuring those 0.25u and 0.5u dose increments. You can always eyeball it. ;-)

Needle lengths are also variable. It's personal preference that comes into play there. I prefer the short 5/16" needle length. Others prefer the 1/2" needle length which you got.

We are being extra cautious with the lantus vial to not contaminate it, not shake it, not roll it, not have it go bad, not drop it on the floor and shatter it on the tile. We want to make it last as along as possible because the darn stuff is too darn expensive. With care, many people can get
4-6 months out of their vial before it loses effectiveness. That is way beyond the 28 days that the manufacturer did testing trials.

Some people don't take all these precautions and do not think they are necessary. It's your choice. Here is a sticky from over in the ISG Lantus TR on handling lantus. http://www.felinediabetes.com/FDMB/viewtopic.php?f=9&t=151
 
Oh, I will def take care with the Lantus. I can't find it for cheaper than $170 in my area. And I think I mentioned I took Bob to see a specialists in another city -an internal medicine dr who specializes in diabetes -because bob could not get regulated. We ruled out pancreatitis, liver problems and she does not feel there is any concern for cushings or acromegaly although we did not specifically test for that. Still waiting on thyroid and a urine panel. However, she only measures insulin by full units. Sooooo, $2000 (on the credit card!!) later I HAVE to trust this doctor. The facility was amazing and they have a great reputation. I just don't think she's an advocate on the tight regulation protocol altho she seems to have alot of success with her patients. She's pretty young as well so I know she's up to date on things. She thinks I should measure the success of the insulin by regularly weighing bob with s baby scale, logging his water and food intake and his daily behavior. Also doing a fructosemine (sp???) test every few weeks. Sorry I'm babbling-just wanted to hear some thoughts....
 
I can't find it for cheaper than $170 in my area.
Now you know why we call it 'liquid gold'. ohmygod_smile

So your vet does not change the doses in less than 1U increments? Is she aware of this vet published study that shows 0.25U and 0.5U changes are better. http://www.felinediabetes.com/Roomp_Rand_2008 dosing_testing protocol.pdf Full article here :http://www.fcv.unl.edu.ar/archivos/...LOGIA 2010/intensiveglucosecontroglargine.pdf

Most of us here have found that increasing in full unit increments will often bypassed a more appropriate lower dose.

She thinks I should measure the success of the insulin by regularly weighing bob with s baby scale, logging his water and food intake and his daily behavior. Also doing a fructosemine (sp???) test every few weeks. Sorry I'm babbling-just wanted to hear some thoughts....
Well, you could do fructosamine tests every two weeks. They average the BG's over a 2-3 week period. If you have a hill, a valley, a hill, a valley, the average is a straight line. Home testing gives you actual real time values.

Is she aware of the AAHA Diabetes Management Guidelines for Dogs and Cats? https://www.aahanet.org/Library/DiabetesMgmt.aspx

The AAHA guidelines say
Home monitoring of BG is ideal and strongly encouraged to obtain the most accurate interpretation of glucose relative to clinical signs.34 Most owners are able to learn to do this with a little encouragement, and interpretation of glucose results is much easier for the clinician. See Table 2 for web links to client educational materials.

A BG curve done at home will cost you about $1 in strips. A fructosamine plus a vet visit every 2 weeks will cost you how much????
 
I will email her with those articles and see what she thinks. I just don't understand why there is such a huge difference in the doctors attitudes towards this. I want my doctor to be on the same page as me!!! Dangit!
 
Print off a copy of those AAHA guidelines for yourself to read. Very informative.

I think I understand them much better now that Wink is OTJ ohmygod_smile and I've been helping people here on the board. Let's me pick out sections to address questions people have.

Your vet does have some good ideas on the tracking food, water, urine, other clinical signs. Harder to track water intake if cat is eating wet food.

Wink went from 2 cups water to none since he is on the wet food. I do probably add a total of 1/4c a day of water to the wet food. They never drink only from the water dish now. Not for 4 months for all 3 of my kitties.
 
Lkldcatlady said:
I was told by my regular vet to draw in tooth prozinc and shoot the rest back in the bottle so I never did all those steps. I'm using Terumo 29 gauge x 1/2" needles 1/2cc. All there are are 4 little marks and then a 5, 4 little marks, then a 10. No half units, right? I don't mean to sound stupid, I'm just amazed at how all the dose is compared to what he was getting with the prozinc and the u40 needle.

I tried to follow all those steps posted and I got lost too! Talk about making something simple into a huge complex project! OK moving on....

I take it you have U100 syringes and on the barrel, the max is 50units.... those do NOT have the half unit markings, but you can use them for doses that are full units, so you can just go and pick up a box of syringes that are 3/10cc with the max of 30units. Be sure to ask for syringes with the 1/2 unit markings.... I usually got the BD syringes and on the end of the box, there was a little diagram showing that the syringes had 1/2 unit markings. You will see 5, 10, 15, 20, 25, and 30 with the same 4 lines on one side, but also more lines on the other side that are staggered.

Anyway, some insulins need to be rolled to mix it, but Lantus and Levemir need no rolling as there's nothing to mix. Alot of people switched insulin and just treated the new insulin the same and had problems.

If you have a vial, some people are not told that they need to replace the insulin they draw out of the vial with air. So, how you put the air into the vial matters if you want the insulin to last for months.
You can have the plunger in the syringe pulled back up to maybe 1unit with air, then with the vial sitting upright, insert the syringe needle into the vial, push the plunger to put the air into the vial, then with the needle still in the vial stopper, turn the bottle upside down and draw out your needed amount of insulin.

For your next purchase of insulin, get the pens or cartridges.... if something goes wrong with your vial, you are out 10ml of insulin and lots of money, but if you have a problem with a pen, you are out only 3ml..... you also don't have to worry about the insulin going bad in the 3ml pens, but with the 10ml vials, it could happen. And you also don't have to worry about the replacing of air because you will see there is no air inside, only insulin.

I am glad you switched to a longer lasting insulin.... let's hope you get to some good numbers now.
There's still a chance that you are dealing with acromegaly, IAA or a combo of both, but put that aside till you know for sure by way of the dose rising high again, and numbers still showing resistance.

Because you were at 4u with prozinc, your starting dose of 2u is just fine.

Prozinc has no depot, shed.... it's an insulin that you give and it's all used up, then the numbers rise and you have to give more. Lantus and Levemir are a bit diff.

To start, you are doing much like medicine your dr gives to you.... you know how you are told you may not feel better for a few days because the meds have to build up in your system? Same deal. You start to feel better maybe around day 3 or 4, yes?

OK, you can give the 2u dose am and pm for at least 3 days, and watch to see how the numbers are going. It's said to hold for 5 days, or 10 cycles, but as you have taken a bit of a reduction in dose, I am thinking by day 4, if you are not seeing any changes in the numbers, you can start your climb in the dosing. Go by the protocol where you raise the dose every 3 days by a 0.5u increase or a 0.25u dose if you are in the 200s and lower. Don't worry about the tiny increases for now as I think you will be fine with the 0.5u increase for a bit.

You do not need to be going to the vet for fructosamine tests.... they are expensive and all they are is the average of your cat's BG numbers over the past 2 weeks. You can get that number from your own meter that you use to test at home; it's not a magical test, so save your money.

You may think you are seeing an awesome specialist but by what you say on the dosing, it does not sound like anyone special to me. Raising a dose by full units is just not right.
What has the cat's weight and measuring food and water intake have to do with home testing and seeing the cat's blood glucose numbers in reaction to the insulin? Are you going to be measuring output as well on a scale? Seriously, what has weight got to do with anything? Many cats lose weight before diagnosis, but you are not new, and a weight gain now would be more indicative of acro because cats with acromegaly do gain weight. How do you know what type of success she has had with others? Are the other owners home testing and there are numbers to prove the cats no longer need insulin or are well regulated? It sounds like they have drawn lots of blood and urine and run a bunch of expensive tests with no findings..... other than what you knew before you paid $2000 and that is the fact that Bob's diabetic.

When you see your vet next, get hard copies of all the tests that have been done and just say you want to keep them in your binder at home as you have been tracking your cat's medical history in case something happens to you. For the big chunk of money you are being charged, the papers should be trimmed in gold.

Forget about cushings; not sure why that was mentioned unless your cat has very very thin skin that rips often.
For the pancreatitis test, find out what was the number result of the fPLI test.
How were liver problems ruled out? Did they do any Xrays or an ultra sound?

The next tests that this specialist wants to do, ask why. Right now, Bob's not sick, is he? He's got diabetes and you are giving him insulin. You will raise the dose slowly and safely until you reach the dose that produces nicely regulated numbers.

By feeding a good low carb wet diet, and giving insulin, Bob can reach regulation, even if his dose is high... no tests are needed, just food and insulin, then maybe tests for acro and IAA if the dose gets higher and gets around 6u am and pm with no improvement in his numbers.

Gayle
 
Thanks everyone for all of the info. It was my choice to see the specialist because I wanted to rule out something that may be causing the diabetes. The specislist's reason for the clinical signs of monitoring (instead of glucose testing) is to avoid stress to the cat. However, bob is pretty laid back and I don't think I'm stressing him so I will continue to test. She did encourage testing if he isn't acting normal or doesn't eat. I didn't agree with everything she had to stay but I still respect her opinions because I'm positive she's smarter than me about this stuff. :-D I will purchase the half unit syringes tho. Makes sense to me to not skip over the correct dose! Just really praying the Lantus works for him. Thanks again for the info!
 
Lkldcatlady said:
Yikes! That's alot of steps!! But ill give it a try tonite. Thanks! I really hope this insulin works better with Bob. The prozinc really didn't do anything....

Hey, it only sounds like a lot of steps. I just walked through my mind what I did when drawing the insulin. I wanted to be detailed and thorough! :lol: :lol: :lol:
 
Actually Deb, it did sound like a lot, but I did it at 7:00 and it wasn't bad at all! It was very helpful actually, because I had no idea- I would have been putting the rest back in the bottle and shortening the life of the liquid gold! :o
 
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