? Neuropathy

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tam with Keith and Kass

Member Since 2015
I adopted an approximately 11-year-old cat last Monday because of diabetes and severe neuropathy. With kitten season coming and no rescues that would take her, I could not just let her die. She is walking on her hocks. She apparently has had diabetes for some time, but for a long time was not on insulin. Her owner went into a nursing home and her son was keeping Daisy locked in the pantry. The clinic did a urinalysis, on 4/23/16, that revealed >= 1000 mg/dl of glucose in her urine and she had a UTI. Interestingly, when I brought her home and tested her BG that first night, she was 67, so I did not give her the 1 unit of insulin. They did two curves there where she was on 1 unit.. One on 5/8/16 with a high of 258 and low of 68. The second curve was on 5/15/16 with a high of 200 and low of 83. They are using the same meter that I have and actually gave it to me. I checked it on my three diabetic cats in remission and it was accurate. I've been checking her two to three times a day and the highest she has been was 108 and lowest 42. She has not required any insulin at all. They were giving her .1cc of B12 in an injection form.

I took her to my vet and had a comprehensive panel done on her. Everything came back normal. No glucose in her urine. All electrolytes and CBC levels normal, kidneys normal. The vet also did a folate/cobalamin test which came back high end of normal. She does not believe the cat needs any B12 at all. I had ordered Zobaline to give to her because of the methylcobalamin.

Her teeth are horrendous and she will need many, if not all extracted. She is still walking on her hocks, cannot jump at all and honestly sometimes seems in pain. I have been trying to massage her legs and work with her slowly. The strange thing is when we put her on the bed, her tail moves really quickly back and forth. In most cats I have worked with, that is a sign of aggression, but she does not even seem aware of it. My vet said she is not in any pain and some function should come back. She had not seen a vet since 2007. I have no idea how long she has had the neuropathy, as she was locked in a pantry by herself with a filthy litterbox. Not much human contact. We are working on getting her to trust us.

My question is would you give her the Zobaline even though the levels of cobalamin are at the upper levels. A friend suggested taking her and getting a full body x-ray to see if something else neurologically could be contributing.

I would really appreciate your thoughts on this mater because I have read about diabetic neuropathy, but have put three cats in remission, but never had a change this fast. My vet recommended not trying to get her more active by having her walk around more. She can't jump. Would you get the x-ray?
 
You might get a 2nd opinion from a teaching school if one is nearby.

That said, B-12, whether it is cyanocobalamin (useful in pancreatitis) or methylcobalamin (useful in diabetic neuropathy) is water soluble and excreted via the kidneys. It is very difficult to overdose on, so it would be pretty safe to try it first.

Does she seem painful at all? Or just unable to extend the legs fully?
 
Sometimes to me she seems really uncomfortable because when we put her on the bed she is constantly trying to move around to find a comfortable place. I have been massaging her legs and she growled once with that. I'm not sure if it is pain but she will do this repeatedly and then her tail will start rapidly going back and forth. I think her legs have been in this position for some time, even though now she is not even getting shots for diabetes.
 
Is it a symmetric problem, ie, both sides are equally affected?
Is any limb cold? (may indicate circulatory problem)
There could be an arthritis component to it causing pain; that might be worth discussing with the vet.
 
Hello. Bless you for helping this kitty. Smokey came from pretty much the same conditions you described except he definitely needed his insulin and had been getting it.

Smokey blood work all came back normal, but I did start the zobaline at twice a day. He was early neuropathy. Didn't walk on hocks but legs were very wobbly and he couldn't get the front legs walking straight. It does take quite awhile to see improvement. Now he gets it once a day.

I don't think it would hurt to give to her. Any excess is urinated out.

She could act that way on a bed because a bed is soft. It would be harder for her to keep her balance and be steady so she might be afraid to be on it as shown by the tail movement. She needs firm flooring under her until she can control her legs better. If it neuropathy, her legs have a mind of their own sort of. She can't control their movement fully.

Zobaline won't hurt her. I'd start with 2 day then when she is walking normally go with one a day.
 
She does walk like that symmetrically with both legs. One other thing I noticed was when she is up she will twitch her tail against something, almost like a cat would spray, but she does not spray. She uses a lower litterbox very consistently.

Thank you for the information on trying the Zobaline. I had read that excess was secreted, so when my vet tagged that on and someone had already picked up the lab samples, I could not believe that one test was $207.
 
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