Need Help Toby's Ketones say small

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Peg and Toby

Member Since 2014
Tested Toby for ketones and the Strip says small ketones. Just started on Levermir 2-1/2 days ago am giving 1 unit 2 times a day. He was on 4-1/2 units 2 times a day. Tested for ketone 2 days ago it was neg. Couldn't get a test yesterday.
Should I call the Emergency vet? Or should I give more insulin? He is acting fine thought he was doing better today. He's been in his pen twice today and following me around the house. Just doing normal cat things. Scared to death. Peg and Toby
 
Just called my vet. who is the nicest lady around. She said as long as he was eating and drinking that we could watch him and if anything changed give her a call. Makes you feel good to have her around. Sorry to put out the 911. I want to thank-you all for your help . Peg and Toby
 
Peg,

I took a look at Toby's spreadsheet. I'm guessing that Toby may need a bit more Levemir. Usually, I'd recommend leaving the dose at 1u for 5 to 7 days since you just started Levemir.

However, with the previous PZI dose of 4.5 and a show of some ketones, I would increase to 1.25 tonight and see if it will lower his numbers and help clear the ketones. You might also grab some unflavored Pedialyte and mix it half and half with his normal water dish. Just helps keep the electrolytes balanced.

If you have fluids to give subQ, that might help as well.

All the best to both of you. I'll check later and tomorrow.

Claudia
 
Toby is still Eating and drinking. He is taking this a whole lot better than I am. Talked to my vet. again tonight and she said he was doing good . She said she would only be worried if he stopped eating and drinking. Told me to call her in the morning to see how he was doing Peg and Toby
 
Last night increased Toby's insulin to I thought 1.25 but think I might of done 1.5. His numbers looked better in the night He started out at 385 at
+4 he was 245 at +6 he was 222 at +8 he was 286 and this morning his ams were 376. He started out a little lower this morning.
Haven't been able to get ketone test yet this morning hoping to get one today. He is still eating and drinking good. I did 1.25
this morning wonder if I should of kept it 1.5? Peg and Toby
 
Peg,

Good job on testing and getting data for Toby. Usually the protocol suggests .25 unit increases, however .5 is probably a good increase for Toby.

Make sure to water his food and keep the water bowls full.

Best!

Claudia
 
Been giving pedialyte like you suggested. Giving him it in the syringe. I give him some every few hours mixed half and half with water. We are seeing more yellows now at +6 today he is at 288 better than all those pinks and reds. you think it's ok to go to
1-1/2 units? He still got a ways to go . Poor guy has been through a lot. Hope this is the insulin for him. Thanks for looking in on us. Peg and Toby
 
Peg,

Glad to help if I can. Do you know how a shed (deposit-based) insulin works? It takes a while for the shed to fill. Then the insulin becomes available to the cat. It can take a few days to a couple of weeks for the shed to be stable.

When you increase a dose of Lantus or Levemir, you will need to wait 3 to 5 days for the increase to be reflected in changes in the blood sugars. It is very different from PZI which is a more immediate change.

Lantus and Levemir are very effective insulins for cats. Just remember it is a marathon, not a sprint. I know patience is so hard when we want our sugar babies to improve right now.

If you have any questions, please post and we'll try to answer them.

Best,

Claudia
 
He was getting 1 unit did you mean to move him up to 1-1/2 units tonight. you said you thought .5 would be good for Toby.
I think that's what he got last night. Was so stressed out I think I gave a half unit thinking was .25 . Peg and Toby
 
Sorry Peg. I didn't get back to answer your last post.

Yes, if I were treating Toby, I would be giving 1.5 units. Hope you get this message before your am shot.

Claudia
 
Peg,

I read your thread on Tight Regulation this morning and realized that Toby is on long term Prednisilone. This drug will probably increase his insulin needs.

Levemir likes consistency, so you will probably want to hold the 1.5 dose for another couple of days. I know the numbers look very high in the morning and the evening. Scary high. But, your mid cycle tests are coming down. Levemir doses are based on the mid cycle tests. So don't be scared or discouraged.

Keep testing for ketones. Use the Pedialyte if he starts throwing ketones again. It will help to flush them. The insulin will do its job in time.

Just curious, where are you from? As you can see, I'm in MA south of Boston.

Take care,

Claudia
 
Claudia, I'm from Cornville,Maine We sound like a real hick town no stores just country. We are just 2 miles from a general
store and 10 miles from shopping center. Probably a lot different from where you live. Want to thank you for all your encouragement. Peg and Toby
 
Claudia, I'm from Cornville,Maine We sound like a real hick town no stores just country. We are just 2 miles from a general
store and 10 miles from shopping center. Probably a lot different from where you live. Want to thank you for all your encouragement. Peg and Toby
 
Hi Peg,

Beautiful country up there. Was a sales rep covering all of Maine in the 80s and 90s. Customers in Farmington and Skowhegan, so I have traveled near you. Where is Harmony in relation to Cornville?

Now back to the business at hand. Toby has been on a totally different kind of insulin. It is going to take some time for him to settle in to the Levemir. The protocol is to start low and raise the dose slowly. That way you don't miss his ideal dose. Give him at least 3 days between dose increases, maybe even 5 days.

If you can settle into a rhythm with Toby, it will improve his numbers. Just keep checking those ketone strips. And encourage him to drink water.

By the way, did you get a vial of Levemir or pens?

Claudia
 
Claudia just tested Toby for ketones he tested moderate called the vet. waiting for reply. I think this change is going to drive me crazy. He is still eating and drinking. Am even syringing more water. How long will it take to build this insulin up in him?
is he on to low of a dose or just hasn't built up yet. I'M about 12 miles south of Harmony. Two miles form Athens. Will let you know what vet. says. Wish us luck, Peg and Toby P.S got a pen lucked out Bought them at wal-mart and they sold me just one so didn't cost so much to start out. Here they come in a pack of five for $400.00 Dollars.
 
hi Peg
just wanted to say hi and hope that Toby starts to get better very soon. what did the vet say about the moderate ketones? please take care.
Nadine
 
Nadine, Vet said as long as he is eating and drinking that he should be alright . If he starts vomiting to give her a call.
Thanks for looking in on us. Peg and Toby
 
I'm not sure if Peg is reading this condo still or others are lurking and reading.

cjleo said:
The protocol is to start low and raise the dose slowly. That way you don't miss his ideal dose. Give him at least 3 days between dose increases, maybe even 5 days.

This is not a correct statement. The protocol has a very specific starting dose based on weight for a newly dx cat. However, for a cat that was on 4.5u of PZI bid, the lev dose should have been started at close to the PZI dose. While normally the starting dose is held 5-7 days, if numbers are high or the kitty is showing ketones or is prone to them, the dose is increased much sooner than that. The dose can be increased every four cycles if necessary by either 0.25u or 0.5u depending on the numbers.

Peg is posting in the TR forum where we will suggest a dose for toby and see how we can safely fast track him and address the ketones.

Edited to add: if a newly dx cat has only been on another insulin (other than lev or Lantus) a very short time (e.g. a couple weeks), then the starting dose for lev or Lantus can, generally, be done using the 0.25u/kg of ideal weight formula with the caveat that if numbers are really high and the cat is throwing ketones, the starting dose might need to be close to the other insulin dose. If a cat has been on an insulin other than lev or Lantus for several weeks or more, the starting dose of Lantus or lev should be close to the other insulin dose depending on the cat and the cats numbers. In the latter case, If the switch is between Lantus and lev, then the starting dose should be 70% of the Lantus or lev dose depending on which the cat is on.
 
Been over in TR trying to figure out what is going on with Toby. Everyone has been very helpful with ketone situation Tested again at 10.00 Pm and he tested small for ketones. been putting food and water to him. Will monitor through the night and give food and water. You think 4.0 units is a good dose for him. Won't take him to low? What numbers do we want to get him in?
Going to take another bg test at + 6 to see what I get. Peg And Toby
 
Hi Peg,

Sorry I didn't catch up with your posts last evening.

I'm not sure I agree with the dosing advice you are getting. If you went from Lantus to Levemir, it would be appropriate to start at or near 4 units. However, BCP PZI is a very different insulin. And, you never got a really good regulated dose from using the BCP PZI.

As your vet says, if Toby is eating and drinking, he is okay even with some trace or small ketones showing. It would seem to me that you might want to get some fluids from your vet to give at home to help flush the ketones during the transition period. Levemir is an excellent insulin but it takes time to "settle".

The dose you gave this morning will not affect Toby's numbers for a cycle or two. The shed Is now using yesterday's insulin doses to affect Toby's bgs today. Does that make sense?

By the way, do you ever travel to Canada? Levemir is much cheaper there...

Just so you know, I recently had a cat throw some ketones over a 3 day weekend. She actually had developed a UTI (diagnosed when I took her to the vet), and I used fluids, insulin and some syringe feeding to keep her out of danger. So I know how scary the ketones can be.

All the best,

Claudia
 
just to let you know, Claudia, when a person switches their cat from Lantus to Levemir, we suggest they drop to 70% of the Lantus dose. Often the cat will need a smaller dose on Levemir than they had on Lantus.
 
We're not talking about a cat going from Lantus to Levemir we're talking about at cat going from BCP PZI to Levemir!

Mel and The Fur Gang
 
cjleo said:
Hi Peg,

Sorry I didn't catch up with your posts last evening.

I'm not sure I agree with the dosing advice you are getting. If you went from Lantus to Levemir, it would be appropriate to start at or near 4 units. However, BCP PZI is a very different insulin. And, you never got a really good regulated dose from using the BCP PZI.

All the best,

Claudia

I'm very aware of Toby's insulin change. My comment was in response to Claudia's comment here that going from Lantus to Levemir, it would be appropriate to start at or near 4 units.

The appropriate dose to start at when you switch from Lantus to Levemir is 70% of the Lantus dose.

That's the point.
 
in the interest of sharing and learning...

i apologize for bumping up an old thread, but this might be a good place to add a comment or two. my comments are based on the assumption kitty's spreadsheet has been studied by members who are experienced and knowledgeable in analyzing spreadsheets and are extremely familiar with the basics as well as the exceptions in the action of the insulin(s) under discussion.

since 2007, we've had more lev kitties come through the TR group than have participated here or in the Lev group itself. we've found (through tons of trial and error and accumulated experience) when kitties have switched from one of the P insulins to Levemir they can *usually* start with a levemir dose which is similar or even the same as their last good "P" dose. since it took 5 units of BCP PZI to pull toby down into double digits, in toby's case that would mean suggesting a dose of about 4 units (for safety's sake we'd suggest a little lower than 5 units, but not too far off 5u because he's ketone prone). iirc, toby's vet also suggested a 4u starting dose of lev.

as already mentioned, when kitty switches from lantus to lev we usually suggest an initial lev starting dose of 70% of the last lantus dose.




addressing the urgency found in toby's case (actively throwing ketones):

ketones can rapidly turn into a dangerous and potentially fatal condition known as DKA (diabetic ketoacidosis).

the recipe for developing ketones = an insufficient supply of insulin + inappetance + infection OR certain other systemic stresses.

  • when kitty is prone to developing ketones and more importantly when kitty is actively throwing ketones... one must get more insulin into the cat without allowing the cat to bottom out. in other words, get the insulin into the cat even if one finds it necessary to feed high carb foods to prevent kitty from dropping too low. starting lev at 1u when kitty was up to 5u BCP PZI before seeing any known double digits is leaving the door wide open for ketones to develop... and sure enough --- that's exactly what happened here. ketones walked right in that open door!
  • getting plenty of food and water into kitty becomes very important. if kitty won't eat talk to your vet about what you can give kitty to stimulate their appetite and/or assist-feeding or a feeding tube if necessary.
  • discuss and address any infection or other problems kitty is having with your vet. also talk to your vet about administering fluids.

keeping ketones at bay can be a lot of work, but oh so worth it!

you're doing an awesome job, peg!
i'll be cheering you and toby on from the sidelines. good luck!
 
Jill & Alex said:
i apologize for bumping up an old thread, but this might be a good place to add a comment or two. my comments are based on the assumption kitty's spreadsheet has been studied by members who are experienced and knowledgeable in analyzing spreadsheets and are extremely familiar with the basics as well as the exceptions in the action of the insulin(s) under discussion.
Just to be clear, cjleo and MommaOfMuse are both experienced and knowledgeable in analyzing spreadsheets and are both familiar with Levemir.

Jill & Alex said:
since 2007, we've had more lev kitties come through the TR group than have participated here or in the Lev group itself. we've found (through tons of trial and error and accumulated experience) when kitties have switched from one of the P insulins to Levemir they can *usually* start with a levemir dose which is similar or even the same as their last good "P" dose. since it took 5 units of BCP PZI to pull toby down into double digits, in toby's case that would mean suggesting a dose of about 4 units (for safety's sake we'd suggest a little lower than 5 units, but not too far off 5u because he's ketone prone). iirc, toby's vet also suggested a 4u starting dose of lev.

This is not the TR forum; this is Relaxed.
 
KPassa said:
Jill & Alex said:
i apologize for bumping up an old thread, but this might be a good place to add a comment or two. my comments are based on the assumption kitty's spreadsheet has been studied by members who are experienced and knowledgeable in analyzing spreadsheets and are extremely familiar with the basics as well as the exceptions in the action of the insulin(s) under discussion.
Just to be clear, cjleo and MommaofMuse are both experience and knowledgeable in analyzing spreadsheets and are both familiar with Levemir.
kay, i purposely didn't mention any names. not sure why you feel the need to single people out. some members get offended easily, feel hurt or slighted when they haven't been recognized, but whatever floats your boat. fwiw, if i were to make a list of names of experienced and knowledgeable members who are well versed in the action of certain insulins it would definitely be longer than yours. personally, i don't find it necessary to name names because they already know who they are. :-D

KPassa said:
Jill & Alex said:
since 2007, we've had more lev kitties come through the TR group than have participated here or in the Lev group itself. we've found (through tons of trial and error and accumulated experience) when kitties have switched from one of the P insulins to Levemir they can *usually* start with a levemir dose which is similar or even the same as their last good "P" dose. since it took 5 units of BCP PZI to pull toby down into double digits, in toby's case that would mean suggesting a dose of about 4 units (for safety's sake we'd suggest a little lower than 5 units, but not too far off 5u because he's ketone prone). iirc, toby's vet also suggested a 4u starting dose of lev.

This is not the TR forum; this is Relaxed.
yes, i'm purr-fectly aware of which forum i am posting in. i have no idea what your point is.
actually, i don't understand what the point is to your entire post. if this is an example of what you're focusing on... you've missed "the meat" of the conversation.

kay, i have to say, you're starting to make me feel uncomfortable. it's beginning to feel much like you're dogging my posts... a lot like you have an axe to grind. :roll:


i certainly wasn't going to call attention to the fact by bringing it up, but since you did...
are there ANY caregivers in this forum (Relaxed) following the "Start Low - Go Slow" Approach... the protocol you've linked as "Relaxed" above?

never mind. it's a rhetorical question...
 
It doesn't matter which forum or which protocol we're talking about. Telling a person whose cat was on 4-5 units bid of Prozinc/pzi to start at 1u of Levemir or Lantus is just plain wrong. Especially if the word "ketones" has ever been mentioned. And especially when their vet suggested starting at 4u when switching.

NOBODY HERE IS A VET. When dka happens, whose fault would that be? As a Mod, I'd like to encourage everyone to reread Rebecca's many posts about advice-giving, encouraging people to work with their vets, and about the legal ramifications of causing harm. Before we get sued.

Carl.
 
Carl & Polly said:
It doesn't matter which forum or which protocol we're talking about. Telling a person whose cat was on 4-5 units bid of Prozinc/pzi to start at 1u of Levemir or Lantus is just plain wrong. Especially if the word "ketones" has ever been mentioned. And especially when their vet suggested starting at 4u when switching.

NOBODY HERE IS A VET. When dka happens, whose fault would that be? As a Mod, I'd like to encourage everyone to reread Rebecca's many posts about advice-giving, encouraging people to work with their vets, and about the legal ramifications of causing harm. Before we get sued.

Carl.
thank you.
ditto on your sentiments...
 
I pointed them out because I didn't want your comment as it stood to be misconstrued that cjleo or MommaOfMuse weren't experienced or knowledgeable.

Jill & Alex said:
kay, i have to say, you're starting to make me feel uncomfortable. it's beginning to feel much like you're dogging my posts... a lot like you have an axe to grind. :roll:
Don't flatter yourself. This is the Relaxed forum where I regularly post.

And as to SLGS, that's linked in the Don't go too fast with the insulin sticky at the top of this forum.
 
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