Need characteristics of remaining available insulins, i.e, onset, peak action, and duration?

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Bob & Simon(GA) & Arthur

Member Since 2019
This is Bob and Simon(GA) circa 2000 to 2011.

After 11 years of 4 diabetics and a gap of 6 years, we have another diabetic.

Of course Humulin U and L, the most used circa 2000 was discontinued in 2005 but we had stocked up and we had a supply into 2011 but not enough to last out for Felix out last diabetic. I mark Felix's decline as starting when we ran out of our stockpile of Humulin L in 2011. He died on August 3, 2011.

Wockhardt has discontinued its Hypurin® Bovine insulin (Lente and PZI) and now there is no appropriate insulin anywhere on the planet for diabetic cats.

Not that it was ever possible to obtain a reliable supply of Hypurin® Bovine as it was not officially approved for use in the USA and the USDA and FDA have flip-flopped on allowing it to be imported for veterinary use. But, that doesn't matter, it has been discontinued.

Lantus - being pushed a lot, basically because vets don't know what else to suggest - was engineered to provide the low basal dose of insulin a health pancreas releases throughout the day. R or other fast acting insulins are still used to handle glucose meal loads but cats have never been treated per human methodologies - i.e. long last insulin to provide basal dose and then a fast acting for meals.

Cats have been treated by trying to find an insulin and dose that will keep them as close to "normal" numbers for as many hours of each day as possible.

Now with a new diabetic, I need insulin characteristics - onset, peak action, and duration for what insulins are still available.

So - can anyone point me at posts which provide good examples of the characteristics of the available insulins effects on DM in cats?

I'm talking about insulin preparations such as Lantus, Humulog, Humulin NPH (often referred to as just N) Humulin 70/30, etc.

Simon's site, which needs a lot up updates, is at www.sugarcatsimon.com

You will note that we were giving our diabetic three doses a day - 0800, 1600, ad 0000

I will give whatever number of doses Arthur needs but I don't have data on the remaining available insulins - I need said information.

The most used glucometer circa 2000 to 2005 (when it was discontinued) was the Bayer Elite or EliteXL.

What meters are most used now and are one or two more utilized than others?

Any assistance will be appreciate.

Bob and Simon(GA), Stranger(GA), Kalib(GA), Felix(GA), and now Arthur.

P.S.

Stranger and Felix joined our family around the age of 13 1/2 years of age (not at the same time) and they both made it to over 20 years with Stranger having been diabetic for about the last 7 1/2 years and Felix for about 8.
 
Hi. Here is a link to insulin information on the AAHA site (click on each to see nadir and duration): https://www.aaha.org/guidelines/diabetes_guidelines/insulin_therapy.aspx Also, there are informational posts on this site at the top of each insulin-specific forum where you can find information about each insulin.

Lantus (glargine) has a very high remission rate, so that may be why it is 'pushed' so much. ProZinc and Levemir (detemir) are others that have great results. These are the three that are considered long-lasting which is probably the reason for their success.
 
This gives characteristics of various insulins in humans
http://ww4.mgh.org/Physicians/Formulary Documents/Insulin Comparison Chart.pdf
I have not seen anything like it for cats.
Regarding meters, the most common meter was the Walmart Relion Confirm or Micro Confirm. Both used the same strips, one was just physically smaller. It required 0.3 uL of blood.
One can still get strips for the Confirms from ADW.
Walmart replacement seems to be their Relion Premier line which includes a compact one, talking one, and one that uses bluetooth to send results to your phone. It does required 0.5 uL of blood.
 
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