MSU VDL testing instructions for IGF-1 and IAA

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Jacques and Pumpkin

Member Since 2023
If you need to have your cat tested for acromegaly/hypersomatotropism (if you don't know what this means, don't worry; someone will let you know when it becomes relevant), here's everything I learned about doing this in the US:

There are two options for these tests: Idexx and the Michigan State University Veterinary Diagnostic Library (MSU VDL). Idexx is a large provider of veterinary diagnostics and handles routine blood testing for a lot of veterinary clinics.

A lot of vets will prefer going through Idexx because Idexx is already integrated with their billing and electronic records systems. I didn't see the price for the IAA test, but the price my vet quoted for the IGF-1 test was over $500. Other people on the board believe the Idexx just reships the samples to MSU VDL. I was too busy at the time to try to figure out the MSU thing on my own, so I went ahead and did the test via Idexx. Idexx lost the sample.

So, for round two I rolled up my sleeves and figured out the MSU VDL approach. They charge $68 for the IGF-1 test and $21 for the IAA test. You have to factor in the cost of the blood draw, and another 50-100 for overnight shipping and packing materials.

Ideally, your vet can set up an account with MSU VDL. If so, then they should be able to handle most of the logistics I cover below. Don't expect to pay $89 for the tests even if your vet deals directly with MSU. Your vet likely charge to draw the blood, to ship the samples, and some sort of markup to cover their administrative costs.

If your vet doesn't want to set up an account with MSU VDL, then hopefully they will be willing to give you a sample to ship in yourself. That's what the rest of this post covers.

If you go on the MSU VDL site, they'll tell you to open an account. Don't bother trying, that's just for veterinary clinics. You have to go with the self pay option.

They'll also tell you the best way to ship is to order packing material from them. Again, don't bother, they only sell packing materials to clinics that have an account with them.

If you call them up, they will strongly discourage you from going to self-pay route. I turned on the waterworks a little and they softened up and walked me through the process.

So, here are the actual steps:

  1. Go to the MSU VDL catalog site (currently https://vdl.msu.edu/Bin/Catalog/Catalog.exe) and search for Insulin. That'll return a few options, including Insulin Like Growth Factor-1 (IGF-1) and Insulin Autoantibodies. These are the two tests you want.
  2. For each of those tests, click the Printable Format link and print out the instructions. You'll want to give these to your vet to make sure they're able to handle the instructions. Your vet needs to be able to centrifuge the blood samples to remove the blood cells, just leaving the serum. I don't know if every vet can do this, but it wasn't a problem for mine.
  3. Meanwhile, you need packing materials, including an ice pack, a sealable plastic bag, a thermal pouch, and some absorbent materials. I ordered them from Amazon: https://www.amazon.com/dp/B07DLX7FGS and https://www.amazon.com/dp/B009W7YA30
  4. Go to the MSU VDL site find the endocrinology submittal form (right now it's at https://cvm.msu.edu/assets/documents/VDL/Submittal-Endocrinology-Fillable.pdf). Hopefully your vet can help you fill out the form, but it's mostly self-explanatory. The tests you want are in the right column on the bottom, under Pituitary (IGF-1) and Pancreatic (Insulin Autoantibodies). For clinic name, put down Self Pay.
  5. Have the vet do the blood draw and centrifuge the serum out of the blood samples. The best day to do this is either on a Sunday or on a Monday morning so that you can get the sample to MSU for a Tuesday. They only run the IGF-1 tests on Wednesdays.
  6. Once you have the samples in vials, wrap them in paper towels, and then put them into a sealable (for example, ziploc) bag. The absorbent material is required in case the vials break in transit. You can read all the requirements for shipping at https://cvm.msu.edu/vdl/submit-a-sample/shipping-requirements-for-submitting-specimens. I summarize them in the next few steps.
  7. Tape the bag to a frozen ice pack. Put it all in the freezer until you're ready to ship if you aren't doing it right away.
  8. UPS doesn't pick up air shipments on Sundays, and MSU isn't available to receive samples on Saturdays or Sundays, so you should ship on Monday-Thursday only. When you're ready to ship, put the frozen samples into a thermal pouch and then pack it carefully in a box. Write "Exempt Animal Specimens" on the side of the box (this says that the box contains blood samples that are unlikely to contain pathogens).
  9. Also include the submittal form from step 4, and a personal check made out to "MSU VDL" (I confirmed this with them on the phone) on the form.
  10. Take the sample to your local UPS or fedex store and ship it overnight/next day. UPS Next Day Air (arrives by the end of the day) is fine per the person I talked to at MSU. You don't need to get it there in the morning. If it's the middle of the summer, you might prefer doing that so it isn't sitting in a hot truck all day.

That's everything I know. I'm currently at step 7. I'll update this thread as I go through the process.
 
Last edited:
If you need to have your cat tested for acromegaly/hypersomatotropism (if you don't know what this means, don't worry; someone will let you know when it becomes relevant), here's everything I learned about doing this in the US:

There are two options for these tests: Idexx and the Michigan State University Veterinary Diagnostic Library (MSU VDL). Idexx is a large provider of veterinary diagnostics and handles routine blood testing for a lot of veterinary clinics.

A lot of vets will prefer going through Idexx because Idexx is already integrated with their billing and electronic records systems. I didn't see the price for the IAA test, but the price my vet quoted for the IGF-1 test was over $500. Other people on the board believe the Idexx just reships the samples to MSU VDL. I was too busy at the time to try to figure out the MSU thing on my own, so I went ahead and did the test via Idexx. Idexx lost the sample.

So, for round two I rolled up my sleeves and figured out the MSU VDL approach. They charge $68 for the IGF-1 test and $21 for the IAA test. You have to factor in the cost of the blood draw, and another 50-100 for overnight shipping and packing materials.

Ideally, your vet can set up an account with MSU VDL. If so, then they should be able to handle most of the logistics I cover below. Don't expect to pay $89 for the tests even if your vet deals directly with MSU. Your vet likely charge to draw the blood, to ship the samples, and some sort of markup to cover their administrative costs.

If your vet doesn't want to set up an account with MSU VDL, then hopefully they will be willing to give you a sample to ship in yourself. That's what the rest of this post covers.

If you go on the MSU VDL site, they'll tell you to open an account. Don't bother trying, that's just for veterinary clinics. You have to go with the self pay option.

They'll also tell you the best way to ship is to order packing material from them. Again, don't bother, they only sell packing materials to clinics that have an account with them.

If you call them up, they will strongly discourage you from going to self-pay route. I turned on the waterworks a little and they softened up and walked me through the process.

So, here are the actual steps:

  1. Go to the MSU VDL catalog site (currently https://vdl.msu.edu/Bin/Catalog/Catalog.exe) and search for Insulin. That'll return a few options, including Insulin Like Growth Factor-1 (IGF-1) and Insulin Autoantibodies. These are the two tests you want.
  2. For each of those tests, click the Printable Format link and print out the instructions. You'll want to give these to your vet to make sure they're able to handle the instructions. Your vet needs to be able to centrifuge the blood samples to remove the blood cells, just leaving the serum. I don't know if every vet can do this, but it wasn't a problem for mine.
  3. Meanwhile, you need packing materials, including an ice pack, a sealable plastic bag, a thermal pouch, and some absorbent materials. I ordered them from Amazon: https://www.amazon.com/dp/B07DLX7FGS and https://www.amazon.com/dp/B009W7YA30
  4. Go to the MSU VDL site find the endocrinology submittal form (right now it's at https://cvm.msu.edu/assets/documents/VDL/Submittal-Endocrinology-Fillable.pdf). Hopefully your vet can help you fill out the form, but it's mostly self-explanatory. The tests you want are in the right column on the bottom, under Pituitary (IGF-1) and Pancreatic (Insulin Autoantibodies). For clinic name, put down Self Pay.
  5. Have the vet do the blood draw and centrifuge the serum out of the blood samples. The best day to do this is either on a Sunday or on a Monday morning so that you can get the sample to MSU for a Tuesday. They only run the IGF-1 tests on Wednesdays.
  6. Once you have the samples in vials, wrap them in paper towels, and then put them into a sealable (for example, ziploc) bag. The absorbent material is required in case the vials break in transit. You can read all the requirements for shipping at https://cvm.msu.edu/vdl/submit-a-sample/shipping-requirements-for-submitting-specimens. I summarize them in the next few steps.
  7. Tape the bag to a frozen ice pack. Put it all in the freezer until you're ready to ship if you aren't doing it right away.
  8. UPS doesn't pick up air shipments on Sundays, and MSU isn't available to receive samples on Saturdays or Sundays, so you should ship on Monday-Thursday only. When you're ready to ship, put the frozen samples into a thermal pouch and then pack it carefully in a box. Write "Exempt Animal Specimens" on the side of the box (this says that the box contains blood samples that are unlikely to contain pathogens).
  9. Also include the submittal form from step 4, and a personal check made out to "MSU VDL" (I confirmed this with them on the phone) on the form.
  10. Take the sample to your local UPS or fedex store and ship it overnight/next day. UPS Next Day Air (arrives by the end of the day) is fine per the person I talked to at MSU. You don't need to get it there in the morning. If it's the middle of the summer, you might prefer doing that so it isn't sitting in a hot truck all day.

That's everything I know. I'm currently at step 7. I'll update this thread as I go through the process.

The vet I’ve been using is not open on Sunday and Monday morning appointments are almost impossible, so there shouldn’t be any reason I can’t go on Saturday and just keep it in the freezer until I ship on Monday morning right?
Not sure that this vets gonna be willing to do this anyway but just in case.
 
The vet I’ve been using is not open on Sunday and Monday morning appointments are almost impossible, so there shouldn’t be any reason I can’t go on Saturday and just keep it in the freezer until I ship on Monday morning right?
Not sure that this vets gonna be willing to do this anyway but just in case.

That should be fine. I believe MSU chucks the sample in the freezer if it arrives early.
 
The vet I’ve been using is not open on Sunday and Monday morning appointments are almost impossible, so there shouldn’t be any reason I can’t go on Saturday and just keep it in the freezer until I ship on Monday morning right?
Not sure that this vets gonna be willing to do this anyway but just in case.

Also, make sure to check out my update here about how to save $100 on overnight shipping costs: https://www.felinediabetes.com/FDMB/threads/msu-vdl-testing-instructions-for-igf-1-and-iaa.277084/
 
Yeah, you’re talking about the “hidden” Next day air saver you mentioned?
I definitely took note of it last night while reading. It’s definitely cool that u took the time to share all of this info. man.
 
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