Pills
Oral medications like Glipizide that stimulate the pancreas, promoting insulin release (or in some cases, reduce glucose production), are less and less used in cats,[14] and these drugs may be completely ineffective if the pancreas is not working. Worse, these drugs have been shown in some studies[15] to damage the pancreas further, reducing the chances of remission for cats. They have also been shown to cause liver damage. Many owners are reluctant to switch from pills to insulin injections, but the fear is unjustified; the difference in cost and convenience is minor (most cats are easier to inject than to pill), and injections are more effective in almost all cases.
The use of oral hypoglycemic agents (glipizide) has been evaluated in diabetic cats. Glipizide is a sulfonylurea that stimulates the release of insulin from functional β cells. Glipizide should not be used in thin or ketonuric cats when absolute insulin deficiency is likely and exogenous insulin administration is required. Glipizide is administered at an initial dose of 2.5 mg, bid, PO, in conjunction with dietary management. Clinical response is seen at 3–4 wk. Short-term success is seen in 50% of treated cats, with longterm success rates (>1 yr) of ~15%. Alternatively, glimepiride and glyburide (other sulfonylureas) may be administered to cats at 2 mg/day (glimepiride) or 0.625 mg/day (glyburide). Acarbose, an oral α-glucosidase inhibitor, has also been used in cats at a dose of 12.5–25 mg, bid-tid, in conjunction with diet and/or insulin to control hyperglycemia.
The Vetsulin was developed for dogs. It does not usually last long enough in cats with their faster metabolism. Success rate for remission for vetsulin is 20-30%. Success rate of remission for Lantus is >90%. No guarantees of remission for any cat, but it's worth striving for in my opinion.Is the vetsilin good?
Good clinical but poor glycemic
control in many cats
• Vetsulin/Caninsulin : Porcine, Lente
• Registered for Vet use – Europe legal
requirement that 1st insulin used
• Many cats good control of signs q12hr
• More accurate dosing
– 40 U/ml versus 100 U/ml
• More predictable than PZI
• In most cats has too short duration
for excellent glycemic control q12hrs
• Remission rates 20-30%
• 4th choice insulin for cats
Lantus has the longer duration and the better success rate.which is better vetsilin or latnus?
Lantus has the better success rate. I know a vial of Lantus can stay good for 4 to 6 months with proper storage, the pens can be usually be used to the last drop and the Lantus insulin has a duration of 14-20 hours in a cat. Don't know how long a vial of Vetsulin stays good for. ETA: the manufacturer website says 42 days before you need to throw out the vial and buy a new one. Duration in most cats is <8-10 hours from what I remember reading.Which has a beter success rate of cats getting off insulin and how long does it last?
Any insulin needs to be given 2x a day, for the best control and chance of remission.Will I have to give her insulin 2x a day?