Long Acting Insulin

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That looks very interesting Elise. I can’t quite work out how they will arrive at a safe dose and once it’s injected it will be there for a week. I see they just want stable diabetics but we know cycles do vary. I guess they are going to monitor BSL for a week first before giving the weekly dose. It would certainly change thinks if it works out.
 
I agree with you, Bron. I think it might work for dogs as from the little I’ve read their dose doesn’t fluctuate as much. It sure would be wonderful if such a thing were possible! Hope all is good with you.
 
Hmm. I immediately went to read, because a once-a-week insulin would be amazing. But they don't name the insulin, just say that it's a new ultra-long. What really caught my eye was their comparison to the current human long-lasting insulins. "Currently, long-lasting insulins are available in human medicine, but the injections only control blood-sugar levels for two or three days." Those would be Lantus and Lev, I'm assuming o_O Although the claim of control over 2 to 3 days with just a long-lasting is -- very misleading. Or outright false. Or Dr. Mahony meant to say 'ultra-long' instead of just 'long'. The human ultra-longs I'm familiar with are Toujeo (insuling glargine u300) and Tresiba (insulin degludec u100, u200), and at least with Tresiba a human can get 2 day coverage -- although it is a once-a-day insulin.

However, I'm in a position to say that Tresiba in cats is very much a BID insulin :cool: Before Dr. Mahony expands the trial to include cats, I hope she takes note of the few of us already using ultra-longs. I know medicine can't progress without trials, but it hurts my heart to think of sugar kitties stuck in a trial where they're not getting nearly enough insulin to keep them healthy. I hope I'm wrong, but... I have a nightmare image of my head of a lot of cats in DKA by the end of their time in the trial.
 
I would hope so, too. Right now with the dogs, though, the study is only checking BG once a week along with insulin levels, and asking owners to check urine periodically for ketones :bookworm: No mention of at-home BG monitoring. That will not work with cats. Personally, I don't think this is too safe for the dogs :facepalm: And I say this as a person that really should be checking my own cat more often.

On the other hand, I've been trying to keep up on Exanatide Extended-Release. That's looking promising, as well. I really hope some of these new options prove-out :joyful: It would be wonderful.
 
Even though I have never had a diabetic dog, if I do ever have one, I would test before every shot. Just like ECID my assumption would be EDID (every dog is different). I have learned a lot from caring for my own cats and this site and know you can't assume every day will be the same.
 
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