I've seen the costs vary quite a bit, some say they can get 1 pen for $50, many pharmacies won't break the 5 pack, and I've seen people say as low as $150 for the 5 pack. I just paid $220 today for a 5 pack. Might have gotten it a little cheaper if I'd shopped around, but I like to patronize my normal pharmacy - I have great pharmacists, and our state is a little weird with pharmacy ownership so we don't have pharmacies in many retail stores like Walmart, Sam's or Walgreens so the cheap competition isn't there.