Insulin and Diet for newly diabetic cat w/ history of calcium oxalate stones?

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Mariah

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Hi everyone,

Sorry this is going to be a LONG post

My cat Xeno was diagnosed with diabetes in September. I found this website shortly after and have been using the advice I've read to guide Xeno's treatment. I've learned a lot and done A LOT of my own research as well, but now I need some advice/opinions on insulin dosage and diet.

ABOUT XENO:
9 years old, 13.5 lbs

  • Up until October 2023, Xeno had few health issues except for dental disease (he's had over half his teeth pulled at this point).
  • Last October, he had a urinary blockage and I took him to the emergency hospital. They inserted a catheter and did an ultrasound, found that he had 4 bladder stones but that the blockage was caused by inflammation. The vets prescribed Hill's Science Diet Urinary Care + Stress, hoping this might dissolve the stones.
  • Two weeks later, he was blocked again and we returned to the emergency room. This time, it was the stones causing the blockage and he had to undergo surgery to have them removed. The stones turned out to be calcium oxalate stones, which cannot be dissolved once they're formed. The vet stressed keeping him on the urinary diet for the rest of his life to prevent stone formation.
  • Fast forward to this September, and I notice Xeno is drinking a ton of water and peeing a lot. I took him into the vet and he was diagnosed with diabetes; his glucose level was at 420 mg/dL.

INSULIN:

The vet prescribed vetsulin starting at 2U twice a day, and said to keep Xeno on the Hill's urinary food. I found this website soon after and was so angry that my vet failed to go over other insulins, food options, home testing, etc. Since diagnosis he's proven to be very uninformed and unhelpful + horrible bedside manner. I have an appointment with a new vet next week, but have been waiting to switch vets until Xeno is somewhat stabilized (our current vet is able to see him very frequently).

After increasing up to 4U of vetsulin twice a day, Xeno's numbers were still in the 300-400s range. After doing research I learned that Lantus (glargine) is a better option because it's longer acting and research shows it has a higher chance of leading to remission. I ended up accidentally dropping and breaking the vile of vetsulin I was using after Xeno had only been on it for a week, so I used that opportunity to ask the vet for a Lantus prescription instead. He said he's never prescribed Lantus before and always uses vetsulin, but I basically demanded we use Lantus after the research I had done.

Xeno started on 2U of Lantus twice a day, and has now been on 3U twice a day for a couple of weeks. After doing a blood glucose curve, my vet got a lowest reading of 195 mg/dL around 7 hours after injection (later than expected). However, that was the LOWEST and the rest of the day his glucose was in the 200s-400s.

HOME TESTING:

My schedule doesn't allow me to do constant readings but I've been trying to do at least one a day at different times of the day. I am now using the Alphatrak 3 for home testing. I initially was using the ReliOn like most people on this website recommend, only to be lectured by my vet that that would not be accurate because it's not calibrated to cats. I've done a lot of research on this and people have differing opinions. However, I have noticed that my Alphatrak 3 consistently provides higher values than the ReliOn (I've tried using them both together to compare). The ReliOn seems to give a reading about 30-40mg/dL lower, so I'm thinking that the Alphatrak IS more accurate.

The lowest reading I've gotten was 178mg/dL, around 8 hours after injection. My other readings tend to be in the 300s still.

FOOD:

Please hear me when I say that I have read all of the advice about diet and have done tons of my own research. I know now that dry food isn't good for cats and that diabetic cats should have a diet low in carbs and high in protein.

Here's where my problem lies: Xeno's diet still needs to prevent calcium oxalate stones from forming, as I literally cannot afford another $6000 hospital visit. In terms of preventing bladder stones, I've read that the food should be low in phosphorus, magnesium, sodium, and calcium. For diabetes, his food should be low carb high protein. Both diets recommend wet food. I've read that many people whose cats have urinary issues+diabetes simply feed a wet food with low phosphorus and low carbs. HOWEVER, I've since learned this is only effective for cats with STRUVITE STONES. I read that for CALCIUM OXALATE stones, their diet needs to be low in calcium and low protein, because high protein diet actually causes more oxalate in the bladder. Additionally, added potassium citrate can help control the amount of calcium in the bladder. So while a diabetic diet is supposed to be high protein, a diet to prevent oxalate stones should be low/medium protein.

The ONLY food I can find that prevents both calcium oxalate stones and is not INSANELY high in carbohydrates is the Hill's Science Diet Glucosupport and the Purina DM. I know many people are against prescription foods, for good reason, as the urinary food Xeno was on turns out to be 40% carbohydrates. However, the Hill's Glucosupport is lower, at 15% carbs (still not ideal) but has the St/Ox Shield to prevent calcium oxalate stones. I have just started Xeno on the Glucosupport dry food and am going to introduce the wet food asap. He has always eaten dry food and hated wet food so it will be a process of trying to transition him.

QUESTION:

Do you think I should increase Xeno's Lantus dosage (to 4U twice a day), and do you have any recommendations for food to control diabetes+ prevent calcium oxalate stones? My vet does not want to increase the dose. I've read that 3U is already a somewhat high glargine dose, but some people go higher if it's not effective enough. Xeno is still drinking and peeing too much, and his glucose only drops below 200 for a couple hours a day. He has glucose present in his urine but no ketones. Despite all of this, he still seems happy and is acting normal.

I'm 24 and practically broke because of this whole situation; I never expected all of this to happen so quickly and am very overwhelmed. I'm doing my best and will do anything for Xeno.

Thank you so much if you took the time to read all of this!! Your input is greatly appreciated!

-Mariah
 
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Hello Mariah, and welcome to you and sweet Xeno.
First a post for you to read: New? How You Can Help Us Help You!
You can summarize information in your signature and help us see the blood sugars you are seeing by putting together a spreadsheet. That post will tell you how to do that. We cannot help you with dose changes without seeing more information from your home testing.

Regarding meters, when I started here, literally no one, not even the vets, used the pet meters. We all used human meters and they were good enough and kept cats safe. The dosing methods we use for Lantus, including one peer reviewed research paper, were developed using human meters. Then the company that made the AT started marketing it heavily to vets. So you'll see a vet saying they are more accurate, but they are close enough to use practically. In normal blood sugar numbers, where it counts, the two meters are fairly close. In high blood sugar numbers, the AT will read higher, but both tell you "the blood sugar is too high". And you'll save a ton of money using the Relion. If your vet wants a curve done you can run the curve with AT and use the Relion the rest of the time.

Where have you been reading about what diet is needed for him? Lots of good info here: https://catinfo.org/feline-urinary-tract-diseases/ The website is written by a vet specializing in feline nutrition.
 
I don't know if you want to try these
Tyler was blocked once, had to take him to the ER ,

the mucus plug, was blocked ,I needed to change his food.
He's been in remission since 1-24-21
The food that was suggested by the ER was too high in carbs so I found this and have been feeding this , never raised his BG and knock on wood hadn't been blocked since

Purina Pro Plan Urinary Tract Health Beef & Chicken Entree flavor Pate

Purina Pro Plan Urinary Tract Health Chicken Entree

They are both low carb and low in phosphorus


The Purina Pro Plan Urinary Tract Health is low carb and low phosphorus
Beef and Chicken Entree pate
Carbs are around 4.80
Phosphorus is 1.44 dry matter

They also have Chicken Entree in Gravy which isn't pate it like tiny pieces of chicken like the size of a chicklet piece of gum lol remember them, they are like tiny tiny chunks
Carbs are 4.5
Phosphorus 0.78 dry matter



Knock on wood hasn't had a problem since Nov 2022
The Chicken Entree
https://www.amazon.com/Purina-Pro-Plan-Urinary-Formula/dp/B003R0LM2U
I have a Pet Smart by me so I just run in there to pick them up
Petco has them too
At least you can buy a few cans and see if she likes it

Here's the Beef & Chicken Entree
https://www.amazon.com/Purina-Pro-Plan-Urinary-Formula/dp/B0170YQ822

My vet said this was a good food to feed Tyler
I always add water to the food
 
I agree with Wendy about the meters. It isn't a matter of accuracy, though. Both meters are accurate. They use a different method for testing blood glucose and as a result, the AlphaTrack reads a bit higher than the Relion. Think of it in terms of measuring temperature in Celsius vs Fahrenheit -- both are accurate but the scale for measuring is different.

We tend to hear more about cats with struvite stones which is what I suspect Diane's providing information about. My thoughts are that if your cat needs to be on a specific diet, that's what you feed your cat. Try to find the lowest carb option. The other issues is that if your kitty is on a higher carb diet, it may prevent him from going into remission. That said, there's no guarantee that any cat will go into remission regardless of whether the caregiver is feeding a low carb diet. However, it does mean that you can get your cat regulated so Xeno can be in a good range for his blood glucose.

This is a link to information on calcium oxalate in cats. It's from one of my favorite sites for feline health information. For some unknown reason (to me) their webpage no longer appears in searches. Given how much research you've done, you may have already come across the page. They also link information to the urolith center at the University of Minnesota. They give some good information about diet and preventative measures.
 
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