Lantus is dosed with the exact same amount every 12 hours.
Lantus is a depot insulin and has carryover into the next 12 hour period.
This means successive doses accumulate.
Therefore, dose changes should be made slowly and carefully.
There is a safe protocol for dose adjustments posted in the Lantus forums.
Adjustments for changing dose times are no more than 30 minutes total, in 1 day.
For safety, test times should always include before you give insulin.
This is so you know it is safe to give it.
For new users, we recommend you do not shoot below 200.
Additional tests around the expected nadir, or low point, help identify if the dose is too high.
This is usually about +5 - +7 hours after the shot.
If your cat tests below 50 during this expected low period, he has earned a dose reduction.
Please read
How to treat HYPOS - THEY CAN KILL! Print this Out!!
Once you have about 5-7 days at the exact same dose, every 12 hours, you can do a curve. This is when you take 12 hours and test from pre-shot to preshot, evey 2 hours for a full curve, or every 3 hours for 'mini' curve.