I don't quite understand what is going on. I was concerned about Missy possibly having low BG tonight as during the day after her morning shot at +6 she reached 113. Tonight after her evening shot at +6 she was 288. It's like the insulin hasn't started working at all. What is going on? Is this normal and will she have days or nights like this? I have been setting my alarm and waking up every two hours to test. I'm thinking with her being at 288 right now I could probably let her go for 3-4 hours without testing her. What do you think? Or should I continue with every two hours? Thanks for any help you can offer. Spreadsheet has been updated for review.