I would also strongly suggest that you get some mid-cycle tests every day to see how low he is going on a dose. Like I said earlier, too much insulin can look like too little insulin when you don't have enough data to know how low a dose is taking him. What happens when the dose is too high is the cat's body fights to stay alive. The insulin may be trying to drive the blood glucose down too low and the pancreas will release stored hormones and sugars to bring it back up fast so too much insulin can actually look like it's not enough! We call this reaction to lower numbers "bouncing".
"Bouncing is simply a natural reaction to what the cat's system perceives as a BG value that is "too low". "Too low" is relative. If a cat is used to BGs in the 200's, 300's, or higher for a long time, then even a BG that drops to 150 can trigger a "bounce". Bouncing can also be triggered if the blood glucose drops too low and/or too fast.The pancreas, then the liver, release glucogon, glycogen and counter-regulatory hormones. The end result is a dumping of "sugar" into the bloodstream to save the cat from going hypoglycemic from a perceived low. The action is often referred to as "liver panic" or "panicky liver". *Usually*, a bounce will clear kitty's system within 3 days (6 cycles)."
We like to suggest getting a +2 (a test 2 hours after the shot), because it can act a lot like a crystal ball in what the rest of the cycle is going to look like.
- If the +2 is about the same as the PS, it's usually going to be a pretty normal cycle....gradually down to nadir and then gradually back up to the next PS.
- If the +2 is a lot higher than the PS, that usually means there's a bounce starting and it's usually OK to take a little bit of a break on testing.
- If the +2 is lower than the PS, that's your "early warning" that it could be an "active" cycle and numbers might go a lot lower later in the cycle and it's important to try to get more tests.
Weekly curves do not always give you an accurate idea of how a cat is doing on a dose. If he is bouncing on the day you do the curve, you will get flat high numbers which does not mean that the insulin is not enough. That is why we like to suggest as many "spot checks" as possible in addition to a curve.