* * * WARNING: UBER-LONG POST * * *
Hi Carol,
The wet food that Saoirse can tolerate is Sheba Fine Flakes in Jelly Poultry Selection (only the chicken and turkey pouches - she has a sensitivity to duck so the poultry and the duck pouches go to my civvie, Lúnasa).
Here's a link to the product nutrition info (a UK supermarket site - there's no nutrition info on the manufacturer's website, which I think is very poor). I give Saoirse a little bit of canned pumpkin with her meals because her GI transit time slowed down a lot when she was off insulin. Also, we went through a patch where she was on Hepaticare and on a different ondansetron generic to her usual one. The constipation made her symptoms much, much worse and we had a fairly rough time of it over Christmas as a consequence. (Saoirse has improved since I was able to get her back onto her regular regimen and the constipation issue has resolved.)
I've had the same food odyssey as yourself. It took me
nine months of food trials before I found the Sheba product. When selecting foods I tried to select products with only basic ingredients - meat, a little bit of fibre, and the basic necessary vitamins and minerals - but it is crazy-makingly difficult to find commercial diets that fit that criterion; so many manufacturers put so many nonsensical ingredients into their products. I want a simple, nourishing cat food, not a candidate for a kitty Michelin Star!!
Of the foods I've tried for Saoirse, she seemed have less difficulty with poultry-based products which were quite bland. Any foods with a very high concentration of offal meat were a major no-no. If I do find a new food to try I open it and smell it first: if the aroma is strong I don't even attempt to give it to Saoirse. She also can't tolerate anything containing salmon oil or sunflower oil. If I get badly stuck she gets on OK with home-poached chicken and the broth from same, but it's not complete. I tried adding a premix product to it (Felini Complete from Zooplus) but the resultant article upset the tums of both Saoirse
and my civvie. I guess the pair of us are in the boat where the 'right foods' are those our little ones can actually
eat. Le sigh ...
Also here's the nutrition data for Hepatosyl from the VSL website. It includes the amount of alfalfa powder in the capsules. The standard dose is 2 capsules a day (but may be increased - ask vet). The two-capsule dose delivers more SAM-e, silybin, and vitamin E per day than the single dose products Samylin or Denamarin. Perhaps if you're interested in whether the small dose of alfalfa might help Murphy it might be an idea for you to consult your vet, a holistic vet or animal herbalist to see if it's OK or contraindicated for him.
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Hepatosyl 50 Ingredients (from the VSL website):
Description: Each capsule contains a comprehensive formula for broader application in hepatic liver support containing S Adenosylmethionine 50MG, Vitamin E (SD) 10MG, Vitamin K1 (PE) 0.05MG, Magnesium Stearate (BP) 2.5MG, Alfalfa Powder 50MG.
http://vsl-labs.co.uk/hepatosyl.html
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While it is generally recommended that SAM-e supplements are given on their own after a minimum 2-hour fast and at least 1 hour before the next feed the manufacturers advise that it's OK to give Hepatosyl with a little food. I find that if I only give a bare scrap of food it doesn't go down as well as if I give about 1½-2 teaspoonsful. Saoirse finds the supplement very palatable. (She seems to like herbal stuff, including SEB.) I read on a human discussion forum that some people find it easier to tolerate SAM-e supplementation if they take it with a little food. In spite of taking it with food they still profess to notice the effects of the SAM-e so I think that it may be more readily absorbed than some of the veterinary manufacturers indicate on their relevant products.
Thank you for advising on the anti-inflammatory effects of Cerenia; I hadn't heard that before. You can only get Cerenia injections over here (and I'm not sure whether it can be dispensed for home administration). Saoirse gets ondansetron every day and it has to be the Bristol Labs generic, else it constipates her.* (A pharmacist who does a lot of pet prescriptions told me that it seems to be the one that best suits cats. The Cipla generic really disagreed with Saoirse.)
I also give Saoirse famotidine (although I'm looking to switch over to slippery elm bark soon, provided I can properly stabilise her) and this does make a difference to her overall comfort BUT if used too long it can negatively affect normal digestion.
Because Saoirse has been diagnosed with early stage II renal insufficiency and because the Sheba food is high in phosphorus I need to give her a phosphorus binder (currently aluminium hydroxide - Ipakitine and ProNefra both cause her GI problems). It's so frustrating not to be able to switch her to a different food because a recipe lower in phosphorus would be enough to control her phosphorus levels without any binder. I give her Moxxor omega 3 oil BID for its anti-inflammatory benefits (from green-lipped mussels, comes in a tiny softgel capsule that is small enough for a cat to swallow and certainly agrees with her better than fish oils), a vitamin B-complex supplement, and 1/3-1/2 of a Zobaline tablet per day. The B vitamins definitely seem to help her appetite, especially B12 (but because of the renal issues I have to be conservative about B12 supplementation). Have you recently checked Murphy's B12/folate levels? Might be worth doing so.
Saoirse can't tolerate probiotics. When If she has to be treated with an antibiotic I will give her a very tiny amount of live organic natural yoghurt but I keep it to a very bare minimum. I assume you've already found the following site, but but I thought I'd include a link to it just in case since it references a study which concluded that probiotics are contraindicated in humans with pancreatitis (and Tanya's Site also cites the same study):
http://ibdkitties.net/pancreatitis.html
Finally, I give Saoirse a supplement called
Nutramed. It contains boswellia, milk thistle and maritime pine bark. All are herbs that are supposed to have anti-inflammatory properties. I've read that boswellia is a popular traditional treatment for humans with IBD on mainland Europe. I don't believe it's available in the States but again it might be something to discuss either with your own vet or a holistic vet/animal herbalist.
I feed Saoirse about 8 small meals a day plus her 2 snacks with her Hepatosyl. I add 2-3 teaspoons of water to each meal. Her food and water bowls are raised and that helped a lot.
Here endeth today's sermon!

Hope it might give you some ideas (and that there aren't any editorial howlers - head's too frelled to proof-read

).
Mogs
* Constipation is a common side effect of ondansetron in humans.
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