Yes, people have. If you search for Bookw0rm's threads, she did it for quite awhile. Generally it is done when a the insulin is only lasting 7-8 hours. It is very time consuming. You have to be positive the number is rising, not dropping and with Bean, I don't see that. He has a curve, it is just a higher one. And sometimes he is still pretty low to shoot by 8/9. TR is much more challenging with ProZinc than with the depot insulins because you aren't looking at a flat, continual curve. ProZinc drops faster and rises faster and adding insulin can really make the cycles volatile.
If he were mine, I would try a sliding scale. So, give the one and 2 drops (I am assuming that is what the 2D means?) or even 1.25 for 350+, one unit for the yellow pre shots. You have some blues in there; they are just a little early in the cycle. Sometimes that can mean a little too little insulin. I'd just be a little more agressive on those higher pre shots, IF you can be around to monitor.