Dehydration, possible pancreatitis and/or UTI

[Blue]

Blue: I did give her an Torbutrol on the 9th and after that she went into a downward spiral.

She had been to her vet that day, had been given cerenia and fluids because she was dehydrated, and when she got home, she went straight for her water bowl, whereas she had not been drinking, just hovering. I thought that meant that her nausea was gone, so I gave her a cyproheptadine to see if it would help her appetite.

A little later she seemed in pain and I gave her a Torbutrol that she had been prescribed back in August. I didn't realize the two meds were bad when used together. This sent her into a downward spiral where she became even more dehydrated and it took several days for the meds to clear, so I haven't given her another Torbutrol out of fear and vet said there was nothing else to prescribe.

I have always checked for interactions... easy enough tool to check which meds don't mix well.
http://www.drugs.com/drug_interactions.html

I had always given Buprenex to my cats for pancreatitis issues; maybe you can ask your vet about it for pain... pancreatitis is very painful, so if your other pain med interacts with other meds, get something different from your vet.

 

[Buff-puff]

Thank you, very helpful tool. Here's what I get when I enter cyproheptadine with either the torbutrol or the buprenex:

MONITOR: Central nervous system- and/or respiratory-depressant effects may be additively or synergistically increased in patients taking multiple drugs that cause these effects, especially in elderly or debilitated patients.

 

[Blue]

if you look just above the MONITOR notes, you will see that the interaction shows as moderate for both.

if you add another drug, tramadol, which is also used by many for other pains, you will see a very different interaction ... MAJOR and there is a fair amount of details below that red MAJOR ! to explain.

if you add another common pain med used for everyday chronic pains, gabapentin, you will see that it does not interact as badly with the rest of the meds in your list.

the drug interaction checker is a very good tool; I check any new med before giving any to my cats.