carlinsc said:
Laurie
I wasn't here when you were beiore, but I am very happy to see that "old time" people have come back lately because experience is the top commodity on the board. I would like your opinion or thoughts about "inverse curves", because I'm sort of on the fence as to what they mean.
1 - how drastic does the upside down smile have to look to be considered "inverse" rather than just flat and within meter variance.
2 - how many times do you need to see one before it makes an impression? How often does it need to show in the numbers before you make a decision relating to dose?
3 - do they always indicate a dose that is too high?
4 - is it something like a "bounce" where you just have to live with it until it clears?
Thanks for any input you can give. For me this place is "all about the learning" so anytime I can file something in the space between my ears, I try to do that.
Thanks!
Carl
Inverse curves can mean too much insulin, but in my experience, most "inverse curves" that people see are not related to too much insulin...they often are just a bounce that makes the curve inverse due to the timing. Likewise with flat curves, they often are indicative of a bounce. I don't look at how drastic the inverse curve is, I look at the
patterns on the SS, it's a picture and one cycle is only a piece of the picture. I have rarely seen cats with inverse curves that are related to too much insulin....not that it can't happen, but it isn't common in my experience here on FDMB.
Bounces can last anywhere from a few hours to a few days...it depends on the cat, and even the same cat can vary. On the Lantus TR forum, we usually tell people to allow up to 72 hours for a bounce to clear. When the bounce clears, the numbers will come back down, and that can happen at any point during the cycle. Sometimes you will see a "late nadir" that is related to the bounce clearing.
If an inverse curve is a bounce, it does not tell you anything about dose. A bounce is simply the liver's reaction to what it
perceives as the cat's BG being too low, OR the BG dropping too fast. The more time the cat spends in the lower numbers, the more it's body gets used to the lower numbers and it becomes the new "normal". The one thing you don't want to do when a cat bounces is raise the dose before that bounce clears. Your cat may end up over dose when the bounce clears, and the numbers could drop low. Wait for the bounce to clear, then see where the nadir ends up before deciding on an increase/decrease.
Let me look for some more info on inverse curves...