Judy and Freckles
Member Since 2019
Condo from 11/30
From @Marje and Gracie
I don’t see a condo for today so I’ll post here.
"Has anyone ever mentioned IAA to you? IAA or Insulin Auto Antibodies is where the immune system sees the insulin as a foreign substance and so attempts to destroy it as it would a virus. That means it’s likely that most of the insulin given isn’t available for the body to use so numbers stay high and flat even as the dose rises. I’m not saying she has IAA but she has “some” insulin resistance.
The only way to know if a kitty has IAA is to test for it which we recommend doing, along with the test for acromegaly when the dose gets to 6u bid. The good thing about IAA is it’s self limiting after a year but there are also other ways to break through it.
My hope is that she’s just developed a little insulin resistance, not IAA, because SLGS has meant she stayed at higher numbers longer. That’s just the nature of the beast quite often. It is what it is. Switching to TR will let you raise the dose faster.
Paws crossed."
Thanks Marje! Freckles did have some blood work done upon the initial diagnosis of FD. Although nothing was said to me by the vet, would any of those results point to IAA or acromegaly? Her test results are on my SS if it helps at all.
From @Marje and Gracie
I don’t see a condo for today so I’ll post here.
"Has anyone ever mentioned IAA to you? IAA or Insulin Auto Antibodies is where the immune system sees the insulin as a foreign substance and so attempts to destroy it as it would a virus. That means it’s likely that most of the insulin given isn’t available for the body to use so numbers stay high and flat even as the dose rises. I’m not saying she has IAA but she has “some” insulin resistance.
The only way to know if a kitty has IAA is to test for it which we recommend doing, along with the test for acromegaly when the dose gets to 6u bid. The good thing about IAA is it’s self limiting after a year but there are also other ways to break through it.
My hope is that she’s just developed a little insulin resistance, not IAA, because SLGS has meant she stayed at higher numbers longer. That’s just the nature of the beast quite often. It is what it is. Switching to TR will let you raise the dose faster.
Paws crossed."
Thanks Marje! Freckles did have some blood work done upon the initial diagnosis of FD. Although nothing was said to me by the vet, would any of those results point to IAA or acromegaly? Her test results are on my SS if it helps at all.
IAA is said to be a self limiting condition, about a year. There have also been acromegalic cats on 1 unit, heck, Neko was below1 unit for quite a while and she had both IAA and acromegaly. The six unit marker for getting the secondary endocrine condition tests done is not a magic number, not all cats with those conditions get to that high a dose, though some get much higher. However, we have had just regular type 2 diabetic cats get to 5.5 units and turn it around. At 6.0, the chances are really good something else is present. Some people get tests done sooner, if there are other possible symptoms present. 