Crackerton update....

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Jen+Crackerton Spunky(GA)

Member Since 2018
Well he threw higher numbers after his body didn’t like the nice 85 he had last night...gonna give it some more time at the lower .75 dose. His neuropathy is really bad. He started a zobaline tonight...what is the max does for really bad cases? He won’t eat crushed in food so it went in with a pill popper...he even rejects miralax in food..never seen a cat do that. Vet is concerned this is not diabetic neuropathy..and I am scared. He has a hard time in litter box
 

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Not sure on dosage of zobaline but I have read that it can take months to reverse sometimes but it will do so eventually. Don't let the vet panic you just yet.

Jones will not even eat food that has a probiotic put into it!:rolleyes:


I would give the .75u at least 4-6 more cycles before deciding to change unless he drops again.

Are you going to use the TR or SLGS method?
 
You can give 2 zobaline a day when neuropathy improves which can take weeks to see you can cut back to 1 pill a day. What is not absorbed is excreted in the urine.
 
http://www.felinecrf.org/vitamin_b.htm#methylcobalamin_what

Methylcobalamin

Vitamin B12 in the form of methylcobalamin may be helpful for diabetic cats, particularly those with diabetic neuropathy. See Vitamin B for more information.
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Vitamin B12 Oral

The oral form of methylcobalamin does seem to work well for CKD cats, though it may be less effective in cats with IBD (inflammatory bowel disease) or pancreatitis. It is common to give a relatively high dose though, to make sure the cat receives enough (any excess should be passed out in the urine).

Oral methylcobalamin is often sold in the form of fruit-flavoured lozenges which some people do use to pill their cats successfully, though plain methylcobalamin tablets and capsules are also available and what I would choose. See below for stockists.

Some methylcobalamin products contain a sweetener called xylitol. Although this is toxic to dogs, there is currently no evidence that it is toxic to cats. However, some people prefer to avoid products containing it.

The Gastrointestinal Laboratory at Texas A&M University says "Since cobalamin is a water-soluble vitamin, excess cobalamin is excreted through the kidneys and clinical disease due to over-supplementation has not been described."

Most people using capsules simply open a 500mcg capsule and mix the contents with their cat's food. Ideally, I would divide this daily dose between two meals a day, i.e. give 250mcg with breakfast and 250mcg with dinner.
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I give 250mcg (1/2 capsule) each cycle mixed with his wet food.

This is what I use
https://smile.amazon.com/gp/product/B0046IET7C/?tag=felinediabetesfdmb-20

It took a good 3 months to see marked improvement and about 6 months to see great improvement
 
@Jen+Crackerton Spunky(GA)

From your picture , that is a classic planter gait. If the vet cannot see neuropathy from this , what the heck does he think it is then?
One of the vets where I take my old Tyler was adamant that what I saw develop over a few months was not neuropathy. It was !

If you look at my signature, you will see that Tyler is a very elderly cat. Before Christmas he had got to the point of mostly scooting as he could not sort out his back legs really. He had quite extreme neuropathy & I did wonder if it would ever come right but it has.

I started him on the B12 methycobalamin tablets + folic acid. I cannot get zobaline here but it is the same thing. After several months Tylers planter gait has completely gone. He can be unsteady because of the one back leg/knee joint but that is muscle wastage and arthritis. Not neuropathy.

When you say having problems with the litter tray, do you mean holding himself so he doesn't plonk down in his poop?


...edit....

Also, once the diabetes is more regulated and the numbers lower from wherever they start out at, that also helps.
 
Not sure on dosage of zobaline but I have read that it can take months to reverse sometimes but it will do so eventually. Don't let the vet panic you just yet.

Jones will not even eat food that has a probiotic put into it!:rolleyes:


I would give the .75u at least 4-6 more cycles before deciding to change unless he drops again.

Are you going to use the TR or SLGS method?

I have tremendous experience with tight regulation of an acromegaly cat using PZI way back in the day. This is the first time with lantus. It is NOT the same...no TID..there is a shed...I am not doing SLGS but may not be perfect at tight reg either..plus we are a week after major dental infection removed..so watching carefully for disappearing diabetes. I was shooting 120 regularly with the acromegaly cat..he had long periods of remission. Hoping I can figure lantus out...and am NOT cavalier...I made a bad decision because I am extremely overtired (other stuff). Hopefully it goes better the next few days...and I get more patient. I have someone with lots of experience helping me dosing til I learn the little things. Hoping I can help him. I will feel better if I can ever get sleep (death in the family)❤️
 
@Jen+Crackerton Spunky(GA)

From your picture , that is a classic planter gait. If the vet cannot see neuropathy from this , what the heck does he think it is then?
One of the vets where I take my old Tyler was adamant that what I saw develop over a few months was not neuropathy. It was !

If you look at my signature, you will see that Tyler is a very elderly cat. Before Christmas he had got to the point of mostly scooting as he could not sort out his back legs really. He had quite extreme neuropathy & I did wonder if it would ever come right but it has.

I started him on the B12 methycobalamin tablets + folic acid. I cannot get zobaline here but it is the same thing. After several months Tylers planter gait has completely gone. He can be unsteady because of the one back leg/knee joint but that is muscle wastage and arthritis. Not neuropathy.

When you say having problems with the litter tray, do you mean holding himself so he doesn't plonk down in his poop?


...edit....

Also, once the diabetes is more regulated and the numbers lower from wherever they start out at, that also helps.
You got it! He lays in pee and poop. We now have waterproof pad under pine litter...which holds his legs above the pee puddle and the pad absorbs it faster..so he is coming out dry..he was a mess with clay litter. But he can’t hold himself with poop...I rescued him last time and helped hold him up. Before that it was pootastrophe...everywhere. He seems a little strange as he does not go to the litter box himself....if I take him there...ensuite bathroom he is like hey there is the box let’s go...it took me a day to realize he didn’t go for 24 hours...poor guy..he held it. Wondering if his neuropathy extends to bladder. I HATE PEOPLE the let him get like this...it damn sure wasn’t overnight....
 
Squallie was having problems holding himself up long enough to use the litter box, too. In his case, it only involved his hind legs, and turned out to be a potassium deficiency rather than neuropathy. Based on your picture, it looks to me like Crackerton is suffering from neuropathy, but it probably wouldn't hurt to get some bloodwork done to make sure it isn't further complicated by a K deficiency.

My condolences regarding the death in your family. :bighug:
 
Poor little guy.:bighug::bighug::bighug:
I haven't had personal experience with Neuropathy but in the time I have been hear I've seen the zobaline work, as others have said it takes time.
How long has he been on insulin? SS is just for a few days, is he recently diagnosed?

I'm sorry for your loss:bighug::bighug::bighug:
 
I am hoping that things will settle down for you and that you'll be able to work with Lantus as well as you could with PZI. When I had to switch Stu (GA) to Lantus after PZI Vet was discontinued it was very difficult at first, primarily because the vet dosed it the way PZI was dosed and poor Stu was way overdosed (too much insulin and raising the dose by a whole unit every week until the poor kitty crashed. That was when I found FDMB!).
Sending lots of healing vines to Crackerton. The dental should help with his insulin needs.

Very sorry for your loss and sending deepest sympathy to you and your family.
 
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