Based off of how she was responding pre-DKA, I don't think hyperT would cause the current dose. I really think it was the DKA and ultra high BGs from that that has caused more of a "temporary insulin resistance". It wouldn't hurt to rule out hyper T though. Make sure they run a regular T4 and a free T4 check. The regular T4 that is a part of the CBC can be thrown off by a concurrent disease, such as diabetes, and show a lower than actual number. The free T4 equilibrium isn't effected by the diabetes. I had this test run on Oscar last month because of some behavior changes and such.