Cliff Notes, pt 1

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MiCo said:
Yeah--I did feed him before I left the house at 8AM, which was +1 from insulin, but had been 3 hours since they ate--my guys are serious grazers. (I think I did a test before feeding at +1, but I forgot to put in SS. Will do that when I get home.)

BUT, I expected a little bounce from last night's BLUES! Just gotta see what the next couple of days bring us. I ended up ordering a new bottle of ProZinc today, because this current one is not going to last much longer with doses up around 6u and 7u. If we end up switching insulin, this might end up being an extra nearly full bottle, but he was going to run out before we made any decisions, so I had to order!
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That's what I would do for what it's worth. :)
 
+5 was 424

I will be home from work soon and will test and try to shoot at +11 (if he will allow) to help get him back on track closer to our normal 4a/4p schedule.

The plumber came to the house today, and I heard from Dave that Cliff got frightened and has been hiding behind the futon most of the afternoon--but that he did eat an afternoon snack back behind there. I wonder if the stress will contribute to higher PMPS #?

Also, thoughts on what to shoot? I know we need to see his BG # first, but is it ok to go back up to 7.25, or should I go to 7.0 units first on my way to 7.25 again? His evening cycles have been so different from his day cycles. In the evening is where we've been seeing yellows and blues towards the end at the +10 +11 and +12
 
The stress can cause a higher BG level, just depends on the cat. But if it wasn't right around shot time, I wouldn't think it would be causing anything. I like the 7u too!
 
Switching back to relion prime, bc we're running low on at2 strips and one of my at2 strip orders got canceled and another went mia during delivery.

Anyways, +3 w relion prime is 337
 
I feel ya on the bottle not lasting long. I was ordering a new one every 4-5 weeks. Just picked up a new one tonight. Hard on the wallet!!
 
+11 191-relion

Amps=216 (relion) | 278-at2
Ate very well
7u

A few things:
  • The combo of lower #s overnight and switching to using the relion meter is hard for me, so I've been using at2 to get (check) his pre-shot #.
  • Definitely still nadiring into blues during pm cycle, but also later. Seems like between +8 and +11
  • I will try to test more overnight tonight or tomorrow. In to weekend will be easier, since I have to work during week. :)
  • Not sure how to dose lately, especially since he's staying higher during day, and going lower at night.
 
Meter-wise, do whatever is most comfortable for you.

He did have a nice preshot this morning. I think your dosing is fine. Have you thought more about getting those high dose condition tests?
 
Most vets think both conditions are rare, but new research is showing that they are not. My vet did not want to waste my money and I finally had to insist on the test. The only place that runs the test is Mich State Universty.
 
Sharon14 said:
Most vets think both conditions are rare, but new research is showing that they are not. My vet did not want to waste my money and I finally had to insist on the test. The only place that runs the test is Mich State Universty.
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Does anyone have recent articles on IGF-1 and IAA, to share with my vet?
I found these links to MSU for the tests.
 
Sharon14 said:
Those are the links for the tests. I'll tag @Wendy&Neko to give you more info. She's one of the high dose gurus in the L&L forum.
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Thanks! I can also post to the Main Health Forum, per Kris' suggestion. Maybe I'll wait and see if Wendy can provide a link first? It would just help me greatly to have this information, and a quick google search and search of the site, I could only find really outdated info.
 
MiCo said:
Also, she mentioned in a follow up email that based on his weight, 8u was the dose at which she would consider him Prozinc resistant. Is it possible he could break thru at 7.25? I hope so!
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My vet told me that based on Neko's weight, it didn't make sense to test for high dose conditions until we got to 10 units. We never did - maxed out at 8.75 units. I had to ask the vet to humour me for the tests. The clinic owner thought I was wasting my money on the "exotic tests". Guess who was most surprised when both the IAA and IGF-1 came back positivie. Not me. ;)

The most recent research on acromegaly is done at the Royal Veterinary College in London, England. Their recent study found that one in four diabetic cats has acromegaly. They were trying to screen these cats out of another study, so weren't looking for acros. They also found that the average dose for these acrocats was 7 units, with a range from 1 unit to 35 units. This post here has a compilation of a bunch of articles on acromegaly. Post #7 by Julie contains the link to the article on the recent research on numbers of acrocats. There isn't a lot out there on IAA, but we do see it often enough that it's worth getting tested - and can change your dosing strategy. If you do get it tested and it comes back positive, let me know and I'll give you my collection of notes on it.
 
Wendy&Neko said:
My vet told me that based on Neko's weight, it didn't make sense to test for high dose conditions until we got to 10 units. We never did - maxed out at 8.75 units. I had to ask the vet to humour me for the tests. The clinic owner thought I was wasting my money on the "exotic tests". Guess who was most surprised when both the IAA and IGF-1 came back positivie. Not me. ;)

The most recent research on acromegaly is done at the Royal Veterinary College in London, England. Their recent study found that one in four diabetic cats has acromegaly. They were trying to screen these cats out of another study, so weren't looking for acros. They also found that the average dose for these acrocats was 7 units, with a range from 1 unit to 35 units. This post here has a compilation of a bunch of articles on acromegaly. Post #7 by Julie contains the link to the article on the recent research on numbers of acrocats. There isn't a lot out there on IAA, but we do see it often enough that it's worth getting tested - and can change your dosing strategy. If you do get it tested and it comes back positive, let me know and I'll give you my collection of notes on it.
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Do you mind me asking, do you remember about how much the tests cost? I see the test amounts listed on MSU's site, but I don't know how much my vet would charge to draw the blood and ship it. If you want to message me direct, that's OK too.
 
I am in Canada, west coast, so the majority of cost that I paid was shipping with an extra (get blood across the border) fee. If you've had a blood draw before done for Cliff, you should know what the charge for that is. And you can always call the clinic and ask first. I've seen recent quotes by people that it was $160-$220, but the shipping charge can be really variable. And some vets charge an extra fee on top for "interpretation". I got a full blood panel done at the same time, so it wasn't a separate fee just for the MSU tests. Summary, your mileage may vary on costs above the MSU fees.
 
My vet charged $125, but only tested for Acro even though I requested both:mad: I printed off the info from the MSU website and brought it to him before my appointment so he could read up on what needed to be done with the blood.
 
Sharon14 said:
My vet charged $125, but only tested for Acro even though I requested both:mad: I printed off the info from the MSU website and brought it to him before my appointment so he could read up on what needed to be done with the blood.
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Thanks, both!
 
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