Tom & Thomas (GA)
Member Since 2018
And this is what my vet dispenses:
https://vetapprovedrx.pharmacy/eloxioral-suspension-generic-meloxicam.html
We used Meloxidyl , here in europe we have a cat version as they do in Austraila which contains 0.5mg per ml(just looked at the vial I have), as @Bron and Sheba mentioned it's a lower concentration than the dog version, regardless though, the injection is only meant to be given once as a loading dose and then follow up with an oral dose, which is calculated by weight. George at 6kg was put on 0.6ml of meloxidyl for his mouth pain, as the inflammation subsided as the AB took effect we kept him on 0.3ml as a maintenance dose until his mouth was healed up after all his extractions, was on it for about a month, we saw no problems with his kidney values worsening, but he did have a squidgy poo, combined effect of the meloxidyl and AB though. I saw an immediate and significant improvement in his mouth pain after the one injection, and was able to manage the pain thereafter with the oral dose.My vet said it would have be done by injection in her office each time
Paul, I have thought (too) about his QOL. Most recently today. I was going to ask you if you think Bronx is happyacupuncture, maybe I'll look into that if nothing else helps. He doesn't mind travelling.
.He looks happy and comfortableLove the bed picture.

What's the point to put him down before trying everything possible

Did nothing for Nelli. I tried, rearched hopingto find a good source. Three different brands sit, now unused, in her cabinet. Ended up being a waste of money... that’s ok though, Nelli is worth itNot really.

still a little shaky on his feet but don't see any other signs that Leo has

ConstipationBronx's constipation issues.
.


BUPEbuprenorphine, but it really was a game changer for Neko. It got her almost a couple years of good quality. Before bupe she was sleepy and not interacting much, after she was up and about and actually played!
@Gill & George ... you are awesomeHey Paul I am so sorry about the hypo, how scary, and sorry that Bronx is in so much pain when moving.
We used Meloxidyl , here in europe we have a cat version as they do in Austraila which contains 0.5mg per ml(just looked at the vial I have), as @Bron and Sheba mentioned it's a lower concentration than the dog version, regardless though, the injection is only meant to be given once as a loading dose and then follow up with an oral dose, which is calculated by weight. George at 6kg was put on 0.6ml of meloxidyl for his mouth pain, as the inflammation subsided as the AB took effect we kept him on 0.3ml as a maintenance dose until his mouth was healed up after all his extractions, was on it for about a month, we saw no problems with his kidney values worsening, but he did have a squidgy poo, combined effect of the meloxidyl and AB though. I saw an immediate and significant improvement in his mouth pain after the one injection, and was able to manage the pain thereafter with the oral dose.
Additionally when I was researching Metacam I found that multiple injectable doses are not recommended in cats. See the US manufacturers recommendations below.
https://www.metacam.com/docs/BIVM-15129MetacamInjectableCATPI_SignOfffnl.pdf
Multiple injections increase the risk of kidney problems and here in Europe multiple injections of meloxidyl are not recommended by the manufacturer either. In cats a single injection followed by an oral dose for post op pain.
And for arthritis an oral loading dose followed by a maintenace dose
See below (taken from the EU info on the product https://ec.europa.eu/health/documents/community-register/2016/20161003136044/anx_136044_en.pdf the pdf is long as it includes all the various forms of metacam available, including that for dogs, cows etc)
1. NAME OF THE VETERINARY MEDICINAL PRODUCT
Meloxidyl 0.5 mg/ml oral suspension for cats
2. QUALITATIVE AND QUANTITATIVE COMPOSITION
One ml of Meloxidyl 0.5 mg/ml oral suspension for cats contains: Active substance: Meloxicam 0.5 mg Excipient: Sodium benzoate (E 211) 2.0 mg For a full list of excipients, see section 6.1.
3. PHARMACEUTICAL FORM Oral suspension. Pale yellow suspension. 4. CLINICAL PARTICULARS
NB the european dosing is per kg (1kg=2.204 pounds)
- 4.1 Target species Cats.
- 4.2 Indications for use, specifying the target species Alleviation of mild to moderate post-operative pain and inflammation following surgical procedures in cats, e.g. orthopaedic and soft tissue surgery. Alleviation of pain and inflammation in chronic musculo-skeletal disorders in cats.
- 4.3 Contraindications - Do not use in pregnant or lactating animals. - Do not use in cats suffering from gastrointestinal disorders such as irritation and haemorrhage, impaired hepatic, cardiac or renal function and haemorrhagic disorders. - Do not use in case of hypersensitivity to the active substance or to any of the excipients. - Do not use in cats less than 6 weeks of age.
- 4.4 Special warnings None.
- 4.5 Special precautions for use Special precautions for use in animals If adverse reactions occur, treatment should be discontinued and the advice of a veterinarian should be sought. 18 Avoid use in any dehydrated, hypovolaemic or hypotensive animal, as there is a potential risk of renal toxicity. Post-operative pain and inflammation following surgical procedures: In case additional pain relief is required, multimodal pain therapy should be considered. Chronic musculoskeletal disorders: Response to long-term therapy should be monitored at regular intervals by a veterinary surgeon. Special precautions to be taken by the person administering the veterinary medicinal product to animals People with known hypersensitivity to Non Steroidal Anti-Inflammatory Drugs (NSAIDs) should avoid contact with the veterinary medicinal product. In case of accidental ingestion, seek medical advice immediately and show the package leaflet or the label to the physician.
- 4.6 Adverse reactions (frequency and seriousness) Typical adverse reactions of NSAIDs such as loss of appetite, vomiting, diarrhoea, faecal occult blood, apathy and renal failure have occasionally been reported. These side effects are in most cases transient and disappear following termination of the treatment but in very rare cases may be serious or fatal.
- 4.7 Use during pregnancy, lactation or lay The safety of the veterinary medicinal product has not been established during pregnancy and lactation (See section 4.3).
- 4.8 Interaction with other medicinal products and other forms of interaction Other NSAIDs, diuretics, anticoagulants, aminoglycoside antibiotics and substances with high protein binding may compete for binding and thus lead to toxic effects. Meloxidyl must not be administered in conjunction with other NSAIDs or glucocorticosteroids. Concurrent administration of potential nephrotoxic drugs should be avoided. Pre-treatment with anti-inflammatory substances may result in additional or increased adverse effects and accordingly a treatment-free period with such drugs should be observed for at least 24 hours before commencement of treatment. The treatment-free period, however, should take into account the pharmacological properties of the products used previously.
- 4.9 Amounts to be administered and administration route Dosage Post-operative pain and inflammation following surgical procedures: After initial treatment with meloxicam 2 mg/ml solution for injection for cats, continue treatment 24 hours later with Meloxidyl 0.5 mg/ml oral suspension for cats at a dosage of 0.05 mg meloxicam/kg bodyweight. The oral follow-up dose may be administered once daily (at 24 hour intervals) for up to four days.
- Chronic musculo-skeletal disorders: Initial treatment is a single oral dose of 0.1 mg meloxicam/kg body weight on the first day. Treatment is to be continued once daily by oral administration (at 24-hour intervals) at a maintenance dose of 0.05 mg meloxicam/kg body weight.
- 19 Particular care should be taken with regard to the accuracy of dosing. The recommended dose should not be exceeded. A clinical response is normally seen within 7 days. Treatment should be discontinued after 14 days at the latest if no clinical improvement is apparent. Route and method of administration Shake well before use. To be administered orally either mixed with food or directly into the mouth. The suspension can be given using the measuring syringe provided in the package. The syringe fits onto the bottle and has a kg-body weight scale (from 1 kg to 10 kg) which corresponds to the maintenance dose. Thus for initiation of the therapy on the first day, twice the maintenance volume will be required. Avoid introduction of contamination during use.
- 4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary Meloxicam has a narrow therapeutic safety margin in cats and clinical signs of overdose may be seen at relatively small overdose levels. In case of overdose, adverse reactions, as listed in Section 4.6, are expected to be more severe and more frequent. In the case of overdose symptomatic treatment should be initiated.
My vet has said to me that he manages numerous cat's with arthritis on small maintenance doses of meloxidyl. We have talked about it as a possibility for George but I'm exploring other avenues at the moment as it gave him very squidgy poo.
As far as I understand in us the oral product is more concentrated (twice as much metacam per ml) and as such you would need to calculate the appropriate dose for a cat. If you use the syringes available with the product which have a weight scale on them you would effectively end up giving Bronx twice the recommended dose. Hope that makes sense.

oooops! @Bronx's dad forgot to attach Motility drug...Constipation
I have read, re-read- (so much info to consume) felineconstipation.org. I’m sure you have too.
I bought a 40lb bag! of the (real, pure) beet pulp fiber (omg, soooo much- I’ll send you a bag of) Found it at our Feed store- horse owner peeps mix it in with the hay, always for older horses.
View attachment 43579 View attachment 43581 View attachment 43582
ALSO, I bought his... started out with tiny 1/8 tsp in Nelli Darwin. She never turned her nose up- walked away. Days later now we are up to 1/4 tsp in two meals a day.
Last but (unfortunately) not least, Nelli was given a motility script. As you know I try if at all possible to avoid chemical rx. This is a temporary drug for Nelli. Goal is to wean offthis as pumpkin and BPF (Fiber is termed a prebiotic because it feeds the probiotics) gets back healthy... gut bacteria
She hadn’t pooped in (- outside most often, hard to monitor)... FOUR days- at least
After 3rd dose, next morning pooped and pooped a good one![]()

As far as I understand in us the oral product is more concentrated (twice as much metacam per ml) and as such you would need to calculate the appropriate dose for a cat. If you use the syringes available with the product which have a weight scale on them you would effectively end up giving Bronx twice the recommended dose. Hope that makes sense.
BUPE
I do have Bupe but worry about it adding to his constipation issues. He hasn't had a real poop now in like 5 days![]()
I bought a 40lb bag! of the (real, pure) beet pulp fiber

Yehl, right!?!!
Amen, so very true- BobbieBut, ECID
@Bronx's dad ... I think Bronx gets this? (Nelli too)- it’s good stuff!why not try egg yolk powder,
GREATI bought him home and within 10 minutes he was doing the stairs and was like a new cat!
!I do have Bupe but worry about it adding to his constipation issues. He hasn't had a real poop now in like 5 days![]()

yes, he does@Bronx's dad ... I think Bronx gets this? (Nelli too)- it’s good stuff!
PS as long as Bronx doesn't have any kidney issues, why not try egg yolk powder, I get it from Foodfurlife.com. It helps with motility. Are you giving a regular constipation remedy?
I agree with the bup and adding to constipation. Bubba suffers with it and the bup made it worse. But, ECID
ETA : Also, are you giving him an Omega 3 oil? I give to my guys every day and I feel it helps big time with arthritis. If I remember correctly, I think you all ready are.
@Tom & ThomasOral suspensions of meloxicam can be found in 0.5 mg/ml and 1.5 mg/ml formulations. I see that in Europe and Australia the packaging is 1.5 mg/ml for dogs and 0.5 mg/ml for cats. But what's important is that the dose for a cat needs to be calculated on the basis of 0.05 mg/kg, possibly with an initial dose at 0.1 mg/kg.
The higher concentration is actually more convenient because it's that much less liquid you have to get into the cat. Using the 1.5 mg/ml version, I only have to give Thos 0.2ml instead of the 0.6ml I would need with the less concentrated form.
...the problem with giving the higher concentration of the metacam...
I believe you! I am so glad Thos is so much better. I found the difference in Sheba nothing short of miraculous.Fair enough, @Bron and Sheba! What matters is getting the right amount of medication into the cat. And that we both found our way there and saw that it could help.
My Thos had no spring left in his hind legs. I had to bodge together some steps so he could climb up to the kitchen counter where the drinking fountain is. Even with a footstool to help he had to pull himself up on my bed. Now he can again jump onto furniture, including a favorite perch on a post from his childhood. Gallop around in the yard. Scramble up trees. And today he took down a squirrel, which demands quite a sprint.
Don’t let your vet give weekly injections of metacam. That would be dangerous. The injection is only meant to be given once as a loading dose. Then a couple of days later you start the oral metacam. You can also just start with the oral. It just takes a few days longer for it to take effect.Thanks! I will ask my vet about this. She said injections only done by her starting with once a week and then stretching it out. I may have to go to an IM to get a script for this oral Metacam. My IM is good and will probably allow me to use it as long as I keep getting BW to see how the kidneys react.
Don’t let your vet give weekly injections of metacam.
Wow! Excellent info. Thank you for posting.If this doesn't persuade your vet, nothing will and I wouldn't trust them to give you any guidance about meloxicam. Let alone administer the drug
So what the dickens is an "IM vet"?
I agree. I'll add a link to this discussion in the 'New to the group?' sticky as well as link it in the Health FAQs forum. Will get to it later tonight.So much good information here. I hope I never have reason to use it, but I've bookmarked this condo just in case. Thanks, guys!
Done.I agree. I'll add a link to this discussion in the 'New to the group?' sticky as well as link it in the Health FAQs forum. Will get to it later tonight.
Thanks Jill. It is a really good thread with lots of useful information in it.Done.
Info is now linked in The Basics: New to the Group? Start here! and INDEX: Health Links/FAQs stickies:
- Metacam/Meloxicam discussions (Strength and Dosing for Cats):
- Metacam ! - Is it safe?
- Bronx's hypo & arthritis thread (discussion begins around Post #80)