When you see extremes in the curves, you want to lessen those smiles to Mona Lisa grins, and if it can't be obtained on PZI, then what's wrong with considering a longer lasting insulin that will result in a smoother curve.
Gayle,
That is the way a Prozinc curve is supposed to look like. On a "perfect curve", the AMPS and PMPS would be the exact same number. It is supposed to look like a smile. Up at both ends, down in the middle. It is intended to taper off between +6 and +12. Otherwise we would get overlap, which is not desirable with P's. P users never see a nice flat lantus curve, until kitty is OTJ anyway.
Carl
it seems that PZI works well for some cats, but others would need to switch to TID in order to get a "nice flat lantus curve". What are the percentage of cats on Ps that go OTJ? I don't think it would feel great for a cat to live a life of extreme curves on P when that cat may be better suited for an L insulin curve.
When a cat's ps is 443, drops to 171 by +4, then starts soaring up to 410 by +12, tells me this cat is on a scary rollercoaster. If you want to stick with this insulin, then you have to do some serious food manipulation to that cliff dive before you hit bottom by +4.
It can be done, but if the cat is still 'running outta gas' way too early in the cycle, maybe it's time to think of time consuming TID, or to switch to a longer lasting insulin.
If a curve has a 300 point range on many cycle, it may be pretty rough on the cat.
I would hope that with an autofeeder, set to give a mini meal hourly between +2 and +6, Kitten's deep curve can be calmed enough to flatten and make Kitten feel better.
By easing the drop, you may see nicer ps numbers and then won't feel a need to increase the dose at all.