Carly has spinal arthritis in the lumbo-sacral joint, and in both knees and elbows, elbows.
I have not done it IM with Carly. Hope had sent me a link about it only being IM, not subQ. I talked to the vet who prescribed it and she was comfy with it SubQ.
Carly was on every 2 weeks but clearly showed pain and limping after one week, so i started doing it every week subq. Prior to the Adequan, she had been yelping in the litterbox, and yelping after jumping on the tree while trying to sit/settle. she does that every so often now, usually right before her next subq shot is due. So I feel that it has helped her a lot. She also gets Dasuquin once a day.