12/26 Shadow AMPS 308 +7 381 +9 338

[Christina Marie]

Shadow went to his vet this past week because after increasing his dose to 6U 2x, his numbers have been a roller coaster. She wanted to "get aggressive" after hearing his home #s and we went ahead and moved him to 6.5U 2x

She didn't run any extra blood tests even though I said I was concerned about a possible infection causing these numbers because she said she just ran a panel on him a couple of months ago.

He has a recheck this Monday where I plan to ask her about sending his blood samples in to test for Acro and IAA.

I'm also concerned that he may just be getting too much insulin, because when we were at 5.5U, he dropped into the 200s more often during his cycles and we even had a low PS one day that was in the 100s.

I'm guess I'm just worried I overlooked something that may just be staring me in the face?

 

[JaxBenji]

Hi! Here's your previous post for continuity - https://www.felinediabetes.com/FDMB/posts/2697928/

With the holidays, the boards are little more quiet but perhaps @Wendy&Neko or @tiffmaxee can stop by when they are back on. You may want to edit your title - like I think you did last time? - and pick the ? from the drop-down and add your question to your title (e.g., "12/26 Shadow - Dosing Help Please").

I'm sure you'll find the right dose and get Shadows numbers down

 

[tiffmaxee]

I’m glad you will be testing for the high dose conditions. He’s not showing signs of getting too much insulin. You would be seeing drops under 50 if that were the case.

 

[Wendy&Neko]

I'm also glad you will be getting testing done for those secondary endocrine conditions (IAA and acromegaly). I don't like calling them "high dose" conditions because there are plenty of cats on smaller doses with those conditions. It's just that if you do get to higher doses, the chances the cat will be positive for one or the other (or both like my girl) are much higher.

As for dose, it looks like too little, not too much. The nature of insulin resistance caused by insulin auto antibodies and by acromegaly, is that it's a changing target. The benign pituitary tumour causing acromegaly can pulse up and down. Mostly up for the initial stages of the condition. The nature the way the antibodies grab onto the injected insulin also mean you have to be aggressive with dose increases to keep on top of the blood sugar numbers. It's very common to see good numbers, then have them fade away. My girl, who had both conditions, first started seeing greens at around 3.5 units, then they faded away, up we'd go in dose, and I may or may not see greens, then the good numbers would fade away so up we'd go again. For months. I called it "the dose going stale". It is very annoying and I also worried about too much insulin. But if you test enough, you would see the numbers dive down low if you were at too high a dose. Since you aren't seeing that, it means the dose is too low.

 

[tiffmaxee]

@Wendy&Neko I won’t call them high definition dose any more.