10/11 Missy

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Maresydotes

Member Since 2011
Missy continues to mystify and amaze me! It is SO nice to see her in these decent numbers more than she is in pinks. She had a little bit of an upward spike yesterday, but she is back down again today. I am so happy with her response to the R, so far. I wish I had tried it sooner. She is giving me hope for regulation, finally. Yay!
 
That is looking good, Do you have a cut off for shooting R? Like maybe 200?

Using R was one of the suggestions on the petdiabeteswikia site for breaking glucose toxicity and the temporary insulin resistance that accompanies it. Hopefully, you are on to something. You may be looking at reducing the dose of one or the other insulin (or both) soon, That 54 is really close to a reduction number.
 
Sheila,
My cutoff on the R is really 300, altho I did give her some a little lower. I don't think I will again, with the way she seems to be going.
My vet was talking that maybe Miss was dealing with glucose toxicity, too. She was in high numbers for a very long time. What I would like to do is see if I can maybe wean her off the R and see if she can maintain these numbers with just the Lev. But, I don't know if that is a good idea. IF she is overcoming glucose toxicity, I wonder if it would be counter-productive to back off on the R just now. I guess I need to read up on it a bit and see if I can figure out what it takes to overcome it.
This is totally uncharted waters for us. I like them, but I am unsure of how to handle it. She had those blips of green in the past, but she has not been stable at all. Now that it looks like she might (anti-jinx) be stabilizing, maybe I can get a plan together on how to handle her. I would love to see her consistently in blues and greens. That is what I would like to aim for.
Well, I guess it is research time for me.....I need to get a handle on glucose toxicity. It sure is nice not feeling so stressed over how high her numbers are. And it is nice to see her doing old behaviors again. :-D
 
TY so much for sharing your "work".
And YAY that she is responding so well ~O)

I will be watching rather closely, as I have not ruled out trying the R myself. I do believe that GT/IR is what's going on w/the boy here.

Was just taking a peek @ur SS. I see that ur dose of R is varied. Can you tell me a little more about how you decide on how much to give? Do you base it on the PS# ?
 
Sheri,
I am no R expert, just so you know. :-D There are a lot of people that know it better than I do. Julie and Punkin and Linda and Weezer in Lantus Tight Regulation comes to mind, but I am sure there are others.
From what I have heard, most cats are very sensitive to R and I was told to start very low and test hourly when you first start them on it. (like the first 4 hours) the theory is that it will bring down their numbers and be gone by the time the Lev kicks in. So, I started her at just a drop and worked up from there. In the beginning I didn't use it at night, because I have MS and fatigue issues, so I can't do a lot of night testing. I wanted to learn how she responded, because nothing about Missy is by the book....even the vets all say that. (another reason to be cautious with the R, if you use it....Dante will probably react differently than Miss)
So, I worked up until I saw some movement in her numbers. She seems to do best on .75, but if she is really high I would give her 1 unit or sort of low, .5. Usually less at night, so I don't worry about a hypo. But, again, don't use my numbers, cuz the FB group I in said Miss uses R like a trouper......I think she is just a high dose kitty, no matter what insulin she is on....and I would guess her weight is a big contributing factor to her resistance. So, Dante would probably not use nearly as much as Miss.
In Wa. State you don't need a prescription for Humulin R. I just went to the pharmacy and asked for it. I was scared to use it, frankly. When Grayson and Lu-Ann started using it and getting results, I got up the courage to try. And it took a little while for it to do what it is doing now.......whatever that is. :lol: I just know that her numbers are SO much better than the last year. Maybe not into green, which I would like, but NOT pink all the time. AND, she is feeling better. More playful, more alert. Even DH notices the difference.
But, remember ECID and maybe you would want to contact Julie or Linda or Lu-Ann and ask their thoughts, too. I wouldn't want to encourage you to do anything to hurt your baby. I didn't try it until I was at the end of my rope and didn't know what else to do. But it looks like, for Missy, to be a good tool and maybe, just maybe, her body is starting to get used to the lower numbers without bouncing so dramatically. She has really only started to do well this past week or so. And, I think, optimally, I should eventually wean her off the R and let the Lev take over, but I have to do some reading on glucose toxicity and see how long I should keep at the R. I would think I would eventually want to increase the Lev to the point it brings her down enough not to need the R.
Sorry to go on and on. I just want you to know that I am a big-time rookie with R and I am not sure what I am doing or going to do in the future.....but I certainly am enjoying her numbers, right now.
If I can help in any way, let me know. We are all in this together. The only reason Missy is still alive today is because of the people here, willing to share their experiences and expertise. I don't have a lot of experience at this, but I am more
than willing to share what we have done.
Good luck with Dante. You are amazing for choosing to foster a FD cat.
 
Oh....and I forgot to report that Miss was 123 @ AMPS and NO R all day yesterday. :-D She really seems on a roll!
 
again, I ty for the info and sharing YOUR experiences. I do realize that ECID and will by no means make any call based on ur use only. Just giving it some serious thought ;-)
And since we have NO idea just how long the boy has been this way........only that he does have neuropathy in both front and back, so he has to have been high for awhile (that sounds funny)

so very glad that you finally found what works for Missy
 
Good morning all -

Missy has done AMAZING with her R... and her numbers in general.

It was not without a LOT of questions and apprehension that I tried R. Because of Grayson's HUGE dose, I started at .5u and have gone as high as 2u. Haven't used it every day. From what I can tell, most people use it on somewhat of a sliding scale. Something like:
under 200 - none
200-250 - .5u
250-300 - 1u
300-350 - 1.5
etc. Of course if you're on a lower dose, I would definitely start with the drop, not .5u; and the no-shoot number may be 250 or 300, depending on how the kitty responds to it, and how much movement they get from the Lev. Grayson doesn't seem to do much on .5 or 1u. But when he was at a 484 preshot, and I gave him 2u, he came down 400+ points....>50% by +4; 67 @+7 :shock: so you REALLY REALLY REALLY need to be cautious in your decision to use, how much to dose, AND your availability to test, as noted above.

As for the withdrawl of R or reduction of Lev, I don't know which is the way to go. I reduced the Lev severely, and am now on the way back up. It's like writing a book... seems the story can go either direction, based on how you decide to write it!

Hoping Missy continues to do well with it!

Lu-Ann
 
Thanks for adding your thoughts, Lu-Ann! I don't want to sound like I know what I am doing.....lots of 'winging it' going on here. :lol: I didn't give her any R if she was below 300, but I have started to add small amounts, lately.
I was trying to increase the Lev so I could maybe stop using the R, but it didn't seem to be working. At 6.75 units she was getting higher numbers than 6.25, so I dropped the Lev back down. But I am adding that touch of R to see if maybe she will get back into blues again.
I hadn't seen the sliding scale, but I might try to incorporate that into our routine.
I also wonder if the recent higher numbers are due to inactivity. She is very overweight (22 lbs when she should be about 14. She really is big-boned...even the vet says that ;-) ) so that adds to resistance, altho she was heavier when she went OTJ. But, I have read that inactivity also raises insulin resistance and it has been cool and rainy here, lately. Missy is definitely a fair weather girl. I am thinking about a leash and taking her out front to explore for some added exercise. Phoenix will jump her if he is outside and sees her out and about. She hates it. When I was taking her out to the back of the yard (1/2 acre, so couple hundred feet) for exercise, she growled the whole way! :o This from a cat who purrs if you just even talk to her...you don't even have to touch her! She can't just sleep on the couch all winter.....and neither can I.
They are definitley mysterious creatures and Miss is one of the most head scratching ones I have seen, esp. For being non-acro/non-IAA. But I know she can do it, I just have to figure out her 'response' trigger.
 
I know you will eventually get there Mares- you are quite persistent when it comes to research :lol:

We are happy she is responding well to the R (well, I'M happy, Sneakers just lays on the couch saying 'you go girl!").

Could the reason her numbers go up if you increase the Lev be because Lev is long acting and R is short? Isn't the reason people use R is to keep the BG down long enough for the regular insulin to kick in? So if you increase the long acting insulin that might be too much for her and kick her into high numbers because it isn't her dose and the R doesn't really affect her that far into her cycle ? I could be totally off base here because I don't know anything about R and this is just what I've picked up on general reading.
 
I think you could be right, Heather. Someone on FB mentioned that also, so I have dropped her back a bit to see what happens. I will give her a few cycles at the lower dose and if I don't see anything good, I think I will go back to 6.25, where she was getting all the nice numbers.
It gets so confusing, because another person said to raise her until she didn't need the R, but from what I saw by raising, it was not what she needed. And if I have to use R to bring her down, so be it. Whatever gets her in decent numbers.
 
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