I don't really know if this is a usual thing! Because the amount of growth hormone being put out by the tumor can wax and wane dramatically, acro cats are known to go through major fluctuations in dose. Occasionally they can even go on and off the juice. I wouldn't say I've seen many do this, though, unless they have had the SRT treatment. Jazzy got up to 14 units on Lantus, and her breakthrough dose on Lev was 13 units. Most of the time I've had her she was on 9-12 units, but once she started living in good numbers all the time, her dose really dropped. That is actually something we see all the time in LL with non-acro cats, so I don't know if this is due to a change in the growth hormone, or the pancreas healing, or something else. I also know that if it is due to the tumor, I could wake up tomorrow and see her insulin needs suddenly increase again and then I'll have to play catchup again.I never knew an acro cat could be on as low a dose as Jazzy. Is this a usual thing? I just saw a video over in health of an FDMB member who's acro cat made her local news. In the video, which was the newscast, she was talking about how big her cat's head and feet were, yet Champ's look bigger than that. I just never thought of it as being abnormal in a cat who's so big all over. I've never even considered getting Champ tested because his insulin needs are much lower than I would think would indicate acromegaly. Now I'm not so sure!! I'd love to hear your opinion.