8/23, Binie, test results

Heike & BInie

Very Active Member
Last post: https://www.felinediabetes.com/FDMB/threads/08-22-binie-amps-444-3-265.293361/#post-3201842

Good afternoon,

sorry, that this is going to be a longer text.

First of all thank you very much to @tiffmaxee, @Wendy&Neko and @Sienne and Gabby (GA) for the insights regarding steroids. I did some research and I also understood, that it can make a bacterial infection worse. But as I understood the vet, she didn't think about it as a treatment option for the infection itself but as a life-safer in case of a sepsis. It seems that this multi-resistant germ they found in january can lead easy to a septic-shock and because I wrote her about Binies unusual behaviour the day before she was scared that she was sliding into something like that. I found some research (for humans) that steroids might (not sure) help in a situation like that. But we didn't give it and I am glad about it because of the reasons you pointed out. If we come into another situation where my vet might think it is appropriate, I know how to challenge her idea now. Thank you!

The antibiogram came back from the lab: Unfortunaltely it is true what the vet suspected: The multiresistant germ enterococcus is still there besides Proteus mirabilis and Escherichia coli. Two rounds of Efex in january and may didn't help. The antibiogram now gives three other options, unfortunately there is one option Binie can't take because she reacts with vomiting immediately. So I am starting with Pradofloaxin tonight and hope that she can take it well and it helps. I also started to do a research about the other option in case the first one fails. It is florfenicol as a vet medicine or chloramphenicol in human medicine. The vet product has to be injected three to four times a day so the vet suggested we try to find the oral medication for humans. Unfortunately it is not approved for humans in Germany and the vet trys to find out how to get it and I am researching as well. If we can not get it at the international market and if the first antibiotic fails, I may end up giving the injections. So the situation is not really great. I asked if we should do ultrasound or an x-ray but she said that it doesn't make really sense because whatever we finde there, first priority is to fight the infection.

The good thing is, that Binie was somehow better today. Seems like the fluids and the pain meds helped. She was lying quite relaxed in her cat bed all day and ate well. Just now she started some hiding again and I just injected some novalgin the vet gave me. Hope it helps. Ketones went down to 0.3 mmol/dl in the the morning at amps.

My questions:

1. I know we are in a situation where the ketones can get up easily and they already did and came down after the fluids yesterday. Therefore I increased her insulin from 1.0 to 1.25 and feeded more carbs in the morning (20% besides her lc food). Today she was high (above 350) all day. I wonder if my strategy with higher carbs is right?

2. Does a second opinion in this situation makes sense? Somehow I feel the situation is clear, there is an infection, we know the germs and which antibiotics to take. We have to cross our fingers they work. Would a second opinion make sense? I wanted to consult an internal medicine specialist online but the earliest appointments are in september. I don't like to drag Binie around for a life consultation, if it doesn't make sense. I know all the vets in my surrounding and I am not convinced they can help. The next clinic is 80 km drive and I know that would be so stressful for Binie.

3. Is there anything more I can do?

Finishing this long text Binie is still in her hiding place. I really hope I can handle what is happening at the weekend. I am on my own here and the vet office is closed. There is an emergency vet in the next town which is open during the day but I don't know if they can do anything for us in this situation. I feel like I have a plan but I am also scared.

Hope everyone is having a good start in the weekend! :bighug::bighug::bighug:
 
Last post: https://www.felinediabetes.com/FDMB/threads/08-22-binie-amps-444-3-265.293361/#post-3201842

Good afternoon,

sorry, that this is going to be a longer text.

First of all thank you very much to @tiffmaxee, @Wendy&Neko and @Sienne and Gabby (GA) for the insights regarding steroids. I did some research and I also understood, that it can make a bacterial infection worse. But as I understood the vet, she didn't think about it as a treatment option for the infection itself but as a life-safer in case of a sepsis. It seems that this multi-resistant germ they found in january can lead easy to a septic-shock and because I wrote her about Binies unusual behaviour the day before she was scared that she was sliding into something like that. I found some research (for humans) that steroids might (not sure) help in a situation like that. But we didn't give it and I am glad about it because of the reasons you pointed out. If we come into another situation where my vet might think it is appropriate, I know how to challenge her idea now. Thank you!

The antibiogram came back from the lab: Unfortunaltely it is true what the vet suspected: The multiresistant germ enterococcus is still there besides Proteus mirabilis and Escherichia coli. Two rounds of Efex in january and may didn't help. The antibiogram now gives three other options, unfortunately there is one option Binie can't take because she reacts with vomiting immediately. So I am starting with Pradofloaxin tonight and hope that she can take it well and it helps. I also started to do a research about the other option in case the first one fails. It is florfenicol as a vet medicine or chloramphenicol in human medicine. The vet product has to be injected three to four times a day so the vet suggested we try to find the oral medication for humans. Unfortunately it is not approved for humans in Germany and the vet trys to find out how to get it and I am researching as well. If we can not get it at the international market and if the first antibiotic fails, I may end up giving the injections. So the situation is not really great. I asked if we should do ultrasound or an x-ray but she said that it doesn't make really sense because whatever we finde there, first priority is to fight the infection.

The good thing is, that Binie was somehow better today. Seems like the fluids and the pain meds helped. She was lying quite relaxed in her cat bed all day and ate well. Just now she started some hiding again and I just injected some novalgin the vet gave me. Hope it helps. Ketones went down to 0.3 mmol/dl in the the morning at amps.

My questions:

1. I know we are in a situation where the ketones can get up easily and they already did and came down after the fluids yesterday. Therefore I increased her insulin from 1.0 to 1.25 and feeded more carbs in the morning (20% besides her lc food). Today she was high (above 350) all day. I wonder if my strategy with higher carbs is right?

2. Does a second opinion in this situation makes sense? Somehow I feel the situation is clear, there is an infection, we know the germs and which antibiotics to take. We have to cross our fingers they work. Would a second opinion make sense? I wanted to consult an internal medicine specialist online but the earliest appointments are in september. I don't like to drag Binie around for a life consultation, if it doesn't make sense. I know all the vets in my surrounding and I am not convinced they can help. The next clinic is 80 km drive and I know that would be so stressful for Binie.

3. Is there anything more I can do?

Finishing this long text Binie is still in her hiding place. I really hope I can handle what is happening at the weekend. I am on my own here and the vet office is closed. There is an emergency vet in the next town which is open during the day but I don't know if they can do anything for us in this situation. I feel like I have a plan but I am also scared.

Hope everyone is having a good start in the weekend! :bighug::bighug::bighug:
Hi Heike, I’m glad to read that Binie seems to be feeling better today. And let’s hope that the antibiotic strain they are giving will help. Will be praying and sending good vibes your way.

It’s good you have a plan and also good. You know where the emergency vet is in case you shouldn’t need them over the weekend. Let’s hope you don’t.

Just one thing I want to mention is that I have read giving fluids can kill the Libre sensor. So if she needs fluids, try to do it on the opposite side of her body if possible away from the sensor. That’s the last thing you need to be dealing with.

I hope you can get the medication needed without too much trouble. Keep us posted.

Try to remain as calm as you can. I know that’s sooo hard. You are doing so great taking care of Binie.
Keep asking questions when you learn more.
Sending you lots of love and support :bighug::bighug::bighug::bighug::bighug:
 
Hi Heike, I’m glad to read that Binie seems to be feeling better today. And let’s hope that the antibiotic strain they are giving will help. Will be praying and sending good vibes your way.

It’s good you have a plan and also good. You know where the emergency vet is in case you shouldn’t need them over the weekend. Let’s hope you don’t.

Just one thing I want to mention is that I have read giving fluids can kill the Libre sensor. So if she needs fluids, try to do it on the opposite side of her body if possible away from the sensor. That’s the last thing you need to be dealing with.

I hope you can get the medication needed without too much trouble. Keep us posted.

Try to remain as calm as you can. I know that’s sooo hard. You are doing so great taking care of Binie.
Keep asking questions when you learn more.
Sending you lots of love and support :bighug::bighug::bighug::bighug::bighug:

Thank you so much for you support Staci! :bighug::bighug::bighug: I didn't know about the fluids and the sensor but it sounds so logical! Thank god she placed the needle in the scruff yesterday and Binies sensor is quite low on her back. So far everything is working fine. But thank god I have spare sensors at home and know how to help me now. But you are absolutely right, that is stress we don't need at all....

Hope you have a relaxed start in the weekend! :bighug::bighug::bighug:
 
Regarding ketones, the issue is that your cat needs to eat. It's not the carbs -- it's calories. Ketones can occur when there's an underlying infection/inflammation + not enough insulin + not enough calories. You can stick with a low carb food but make sure your cat is eating or use a food that is higher in calories.
 
Regarding ketones, the issue is that your cat needs to eat. It's not the carbs -- it's calories. Ketones can occur when there's an underlying infection/inflammation + not enough insulin + not enough calories. You can stick with a low carb food but make sure your cat is eating or use a food that is higher in calories.

Thank you Sienne! Seems I misunderstood the concept somehow. So I will switch back to only low carb as long as I can keep her eating. That helped a lot! :bighug::bighug::bighug:
 
0.6 and 0.3 for ketones are both low levels. You can keep an eye on it, but I wouldn't worry at that level. You can also make sure she stays hydrated by adding a little extra water to her food. That water will help flush any ketones.

Is Binie getting a probiotic to help with the GI side effects of the antibiotic? Give a couple hours apart.

As far as a second opinions, it depends. I really liked Neko's internal medicine vet when she got more "complicated" by adding heart disease and small cell lymphoma to her list of conditions. He was really good at balancing all her conditions and prioritizing them and her meds for me. Neko's general practice vet said she could treat, but recommended I go to the IM vet and I was glad she did as they had more equipment to do diagnosis in house. You have to decide if you think the travel/expense might mean a different approach.
 
0.6 and 0.3 for ketones are both low levels. You can keep an eye on it, but I wouldn't worry at that level. You can also make sure she stays hydrated by adding a little extra water to her food. That water will help flush any ketones.

Is Binie getting a probiotic to help with the GI side effects of the antibiotic? Give a couple hours apart.

As far as a second opinions, it depends. I really liked Neko's internal medicine vet when she got more "complicated" by adding heart disease and small cell lymphoma to her list of conditions. He was really good at balancing all her conditions and prioritizing them and her meds for me. Neko's general practice vet said she could treat, but recommended I go to the IM vet and I was glad she did as they had more equipment to do diagnosis in house. You have to decide if you think the travel/expense might mean a different approach.

Thank you so much Wendy! I always get worried if Binie ketones rise above her "normal" range, which is usually quite low but it's good you helped me to gain perspective about that.

Good you reminded me about the probiotics. I just stopped them a few days ago after the last round of antibiotics but I will start them again. You are right, that internal medicine vets have more equipment. I didn't think about that and maybe one day that is an advantage for us. For now I think I will try an online vet first and if they think we have to do further diagnostics, it may be worth the travel. I hope you have a nice afternoone! :bighug::bighug::bighug:
 
Last post: https://www.felinediabetes.com/FDMB/threads/08-22-binie-amps-444-3-265.293361/#post-3201842

Good afternoon,

sorry, that this is going to be a longer text.

First of all thank you very much to @tiffmaxee, @Wendy&Neko and @Sienne and Gabby (GA) for the insights regarding steroids. I did some research and I also understood, that it can make a bacterial infection worse. But as I understood the vet, she didn't think about it as a treatment option for the infection itself but as a life-safer in case of a sepsis. It seems that this multi-resistant germ they found in january can lead easy to a septic-shock and because I wrote her about Binies unusual behaviour the day before she was scared that she was sliding into something like that. I found some research (for humans) that steroids might (not sure) help in a situation like that. But we didn't give it and I am glad about it because of the reasons you pointed out. If we come into another situation where my vet might think it is appropriate, I know how to challenge her idea now. Thank you!

The antibiogram came back from the lab: Unfortunaltely it is true what the vet suspected: The multiresistant germ enterococcus is still there besides Proteus mirabilis and Escherichia coli. Two rounds of Efex in january and may didn't help. The antibiogram now gives three other options, unfortunately there is one option Binie can't take because she reacts with vomiting immediately. So I am starting with Pradofloaxin tonight and hope that she can take it well and it helps. I also started to do a research about the other option in case the first one fails. It is florfenicol as a vet medicine or chloramphenicol in human medicine. The vet product has to be injected three to four times a day so the vet suggested we try to find the oral medication for humans. Unfortunately it is not approved for humans in Germany and the vet trys to find out how to get it and I am researching as well. If we can not get it at the international market and if the first antibiotic fails, I may end up giving the injections. So the situation is not really great. I asked if we should do ultrasound or an x-ray but she said that it doesn't make really sense because whatever we finde there, first priority is to fight the infection.

The good thing is, that Binie was somehow better today. Seems like the fluids and the pain meds helped. She was lying quite relaxed in her cat bed all day and ate well. Just now she started some hiding again and I just injected some novalgin the vet gave me. Hope it helps. Ketones went down to 0.3 mmol/dl in the the morning at amps.

My questions:

1. I know we are in a situation where the ketones can get up easily and they already did and came down after the fluids yesterday. Therefore I increased her insulin from 1.0 to 1.25 and feeded more carbs in the morning (20% besides her lc food). Today she was high (above 350) all day. I wonder if my strategy with higher carbs is right?

2. Does a second opinion in this situation makes sense? Somehow I feel the situation is clear, there is an infection, we know the germs and which antibiotics to take. We have to cross our fingers they work. Would a second opinion make sense? I wanted to consult an internal medicine specialist online but the earliest appointments are in september. I don't like to drag Binie around for a life consultation, if it doesn't make sense. I know all the vets in my surrounding and I am not convinced they can help. The next clinic is 80 km drive and I know that would be so stressful for Binie.

3. Is there anything more I can do?

Finishing this long text Binie is still in her hiding place. I really hope I can handle what is happening at the weekend. I am on my own here and the vet office is closed. There is an emergency vet in the next town which is open during the day but I don't know if they can do anything for us in this situation. I feel like I have a plan but I am also scared.

Hope everyone is having a good start in the weekend! :bighug::bighug::bighug:
I’m sorry you are having this issue. I’m rather confused because an antibiogram usually tells the vet what organisms are susceptible for treatment by what antibiotics. An antimicrobial susceptibility provides information about the antimicrobes in a specific being. You would use the susceptibility to see what she has and the antibiogram to see what drugs might treat it. At least, that is my understanding.

I’m sorry I haven’t kept up to know where they found these bacteria in her.....her urinary system? I did find this about E. coli. It has a long list of antibiotics that can be used and I wonder if these can be cross referenced on the antibiogram?
 
I’m sorry you are having this issue. I’m rather confused because an antibiogram usually tells the vet what organisms are susceptible for treatment by what antibiotics. An antimicrobial susceptibility provides information about the antimicrobes in a specific being. You would use the susceptibility to see what she has and the antibiogram to see what drugs might treat it. At least, that is my understanding.

I’m sorry I haven’t kept up to know where they found these bacteria in her.....her urinary system? I did find this about E. coli. It has a long list of antibiotics that can be used and I wonder if these can be cross referenced on the antibiogram?

Thank you so much Marje! I understand your confusion. I am still confused too. The urine was tested four times to get a result. The first time I used medical litter to catch the urine, the second and third time I was catching it while she peed in a sterile cup and the fourth time the vet was taking it directly from the bladder. Each time (also when the vet took it) the lab wrote the following text (I used a translator):

"mixed flora
Numerous different bacterial species were detected in the urine
bacterial species were detected. Bacterial urinary tract infections
urinary tract infections are usually diseases caused by one or a few different species.
caused by one or a few different species. The
The findings therefore indicate secondary contamination of the urine with
mucosal or environmental germs. An assessment of pathogenicity is therefore
is therefore not possible in this context. Should you nevertheless
wish a differentiation of the germs detected (only useful for sterile
sterile sampling), please inform us immediately."

The fourth time the vet asked the lab to differentiate the germs and they found three germs: enterococcus, Proteus mirabilis and Escherichia coli.

The whole process took some time because I always had to bring in another urine sample. They always gave me the information, that the urine was contaminated and I was really confused, because I couldn't see what I did wrong. After the first urine test my vet suggested to give just any antibiotic, to not loose to much time. Today I think that was a mistake and I still don't understand what went wrong with the urine samples. Even when the vet took the urine with a needle directly from her bladder, they wrote the text above. I am still confused from all this and feel someone did a mistake. But I think it doesn't make much sense now to question the past. We know which antibiotics to take, unfortunately there is not much choice. Thank you for the info about e.coli! It also mentions the antibiotics the antibiogram suggests. Unfortunately we have to find an antibiotic, which works for all three germs and that makes it more difficult.

Hope you have a nice evening! :bighug::bighug::bighug:
 
Thank you so much Marje! I understand your confusion. I am still confused too. The urine was tested four times to get a result. The first time I used medical litter to catch the urine, the second and third time I was catching it while she peed in a sterile cup and the fourth time the vet was taking it directly from the bladder. Each time (also when the vet took it) the lab wrote the following text (I used a translator):

"mixed flora
Numerous different bacterial species were detected in the urine
bacterial species were detected. Bacterial urinary tract infections
urinary tract infections are usually diseases caused by one or a few different species.
caused by one or a few different species. The
The findings therefore indicate secondary contamination of the urine with
mucosal or environmental germs. An assessment of pathogenicity is therefore
is therefore not possible in this context. Should you nevertheless
wish a differentiation of the germs detected (only useful for sterile
sterile sampling), please inform us immediately."

The fourth time the vet asked the lab to differentiate the germs and they found three germs: enterococcus, Proteus mirabilis and Escherichia coli.

The whole process took some time because I always had to bring in another urine sample. They always gave me the information, that the urine was contaminated and I was really confused, because I couldn't see what I did wrong. After the first urine test my vet suggested to give just any antibiotic, to not loose to much time. Today I think that was a mistake and I still don't understand what went wrong with the urine samples. Even when the vet took the urine with a needle directly from her bladder, they wrote the text above. I am still confused from all this and feel someone did a mistake. But I think it doesn't make much sense now to question the past. We know which antibiotics to take, unfortunately there is not much choice. Thank you for the info about e.coli! It also mentions the antibiotics the antibiogram suggests. Unfortunately we have to find an antibiotic, which works for all three germs and that makes it more difficult.

Hope you have a nice evening! :bighug::bighug::bighug:
Thank you for explaining. I hope you can find an antibiotic that works.
 
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