6/12 Henry C, AMPS=454, PMPS =Red All Day

Roxana & Henry

Roxana & Henry

Member Since 2022
Yesterday's

Today was the 3rd cyle at the new dose so I thought he would dive low but nope, all red. Of course it happens only during the night not the day. And only during the work week. I mean who needs sleep anyways lol. Super picky with food today but did eat well. Taking it one day at a time.
 
Most likely. Almost PM+4 and 376. I should be grateful I get to sleep and not complain I guess.:cat: I talked to the vet about maybe doing the IIA test in 2 weeks when I go back for a new Libre. I was also wondering if it is worth doing another acromegaly test. He tested negative when he was first diagnosed but the vet said in certain cases there could be some false negative results if the test is done when cat is newly diagnosed. Any thoughts on that? I maybe overly paranoid.
 
Bandit's Mom said:
We ask CGs to test for secondary conditions like acromegaly and IAA when the cat gets to 6U. Henry is not there. He is probably close to a breakthrough dose. Hang in there.

Sharing Gumung's SS (which you might have already seen). He went up to 6U and turned around and there has been no stopping him since.
https://docs.google.com/spreadsheet...iZPzcYph7SlVOxU7zR744aV5E/edit#gid=1182885903

Tagging @Wendy&Neko since she is our got-to person for acro/IAA.
Click to expand...
Thank you Bhooma, this is very helpful. Glad to see other kitties doing well despite getting first to a higher dose. Henry was on 5 units before and he was seeing green and probably fake libre hypos. So I think you are right. Paws crossed!
 
The acro test can have false negatives if done too early after starting insulin. From another post I did: results given in this presentation by Dr. Vanessa Woolhead of the RVC. First of all, positive for acromegaly is greater than 1000 when measured in nmol/L, as done in England at RVC. She studied over 200 cats. 19% of the cats had IGF-1 over 1000 when tested early after starting insulin therapy. A further 9.1% changed from <1000 to >1000 after 73 days of insulin therapy. So approximately 1/3 of acrocats tested too early got false negative results. Something in starting insulin therapy temporarily lowers IGF-1 numbers.

If I was going to get testing done for IAA, I would get the acro (or IGF-1 test) done at the same time. The blood for both tests goes to Michigan State University and no need to pay for shipping costs twice. You can wait for 6.0 units, or you can test earlier if you want. We've had cats positive for acromegaly and IAA on less than 6 units. It's just that if you get to 6 units, chances are one or the other or both will be positive. Other things to make sure you've checked is whether Henry needs a dental, and also recent bloodwork to check for hyperthyroidism, though picky at food seems to counter that thought. Those and pancreatitis, kidney disease and heart disease can also cause insulin resistance.
 
Wendy&Neko said:
The acro test can have false negatives if done too early after starting insulin. From another post I did: results given in this presentation by Dr. Vanessa Woolhead of the RVC. First of all, positive for acromegaly is greater than 1000 when measured in nmol/L, as done in England at RVC. She studied over 200 cats. 19% of the cats had IGF-1 over 1000 when tested early after starting insulin therapy. A further 9.1% changed from <1000 to >1000 after 73 days of insulin therapy. So approximately 1/3 of acrocats tested too early got false negative results. Something in starting insulin therapy temporarily lowers IGF-1 numbers.

If I was going to get testing done for IAA, I would get the acro (or IGF-1 test) done at the same time. The blood for both tests goes to Michigan State University and no need to pay for shipping costs twice. You can wait for 6.0 units, or you can test earlier if you want. We've had cats positive for acromegaly and IAA on less than 6 units. It's just that if you get to 6 units, chances are one or the other or both will be positive. Other things to make sure you've checked is whether Henry needs a dental, and also recent bloodwork to check for hyperthyroidism, though picky at food seems to counter that thought. Those and pancreatitis, kidney disease and heart disease can also cause insulin resistance.
Click to expand...

His recent blood work was good, no sign of any other disease (not sure heart disease how it would show on blood work but his labs were mostly normal they are in the spreadsheet). Vet said teeth were ok could use a cleaning but not bad. I asked about a cleaning and and vet was not eager to recommend we do it, she seemed worried about anesthesia at his weight with diabetes (18 pounds now). Hopefully he will start see better numbers if not I will ask for both tests.
 
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