04/19 Eddie AMPS 182 +3 236 +5 277 PMPS 337 +2 268 +3 243 (did increase)

Jodey&Eddie&Blue

Jodey&Eddie&Blue

Member Since 2021
Good morning! I was worried about how Eddie would be feeling this morning as I had to make a decision last night about dosage. You'll recall the vet said they had given him 1u in the morning and recommended 7u and I wasn't comfortable with that right off the bat. I thought I'd rather shoot low because he has been through so much and I was just being cautious. I hadn't heard yet from @Wendy&Neko and it was getting late. A few folks said go between 4.5u-7u and R.L. was for the conservative dose that I was at first proposing. 2u.

Anyway, long story short, I went with my gut and did 2u. I thought better to have high numbers than to risk a hypo and in his case I think another vet visit would have done him in.

This morning I test and got 182! I was certain it was going to be a much higher yellow and was totally surprised So, even though I've shot full dose at blue before, I just thought I'd follow my intuition and shoot 2u again. Don't ask me why. If it doesn't work out, I can increase as JL suggested.

I'm looking at Eddie and watching him walk and I can see this week has been really hard on him. The good news is that he took his other medications, ate a whole breakfast, used the kitty box and is now sitting in the living room on his favourite chair.

Here is yesterday's story. Please note that I was posting on the wrong date and the whole discussion of insulin is on the 04/17 thread.

04/18
https://felinediabetes.com/FDMB/thr...om-the-hospital-hes-home.262190/#post-2939431
04/17
https://felinediabetes.com/FDMB/threads/04-17-eddie-update-hospitalization-and-question.262145/

Thank you again, everyone, for being so supportive.
 
Ok, so my experiment might be suggesting I start to increase. At +3 236 and I'll test again and see what PMPS brings as well. He's doing well but seems a bit uncertan about going to his usual place to eat. I brought his snack to him, which he ate. Slowly, slowly...
 
Eddie has been through a huge amount this week. I think you are right that he needs a time out from vet visits as much as is possible.

Did you get any tests last night? preshot or later? By the way, when you increase, you aren't starting over and going up by 0.25 units. You can jump much closer to what you think is a good dose. Traditionally after a reduced dose for vacation or whatever reason, we suggest going back to the last good dose.

Please check ketones daily the next couple days if you can. Slow appetite, infection, too little insulin are a bad combo.
 
Wendy&Neko said:
Eddie has been through a huge amount this week. I think you are right that he needs a time out from vet visits as much as is possible.

Did you get any tests last night? preshot or later? By the way, when you increase, you aren't starting over and going up by 0.25 units. You can jump much closer to what you think is a good dose. Traditionally after a reduced dose for vacation or whatever reason, we suggest going back to the last good dose.

Please check ketones daily the next couple days if you can. Slow appetite, infection, too little insulin are a bad combo.
Click to expand...

I didn't get any tests last night. I decided to just give him the 2u and let him be. He had just come home from the clinic and I got him to eat, which felt like a miracle. I could see he was exhausted. I thought even if I miss what happens overnight, it's not the worst thing.

So here we are today. I didn't know that I could increase without those increments and so I will probably increase tonight after I see how the day goes.

Thanks, Wendy.
 
Jodey&Eddie said:
I'm looking at Eddie and watching him walk and I can see this week has been really hard on him. The good news is that he took his other medications, ate a whole breakfast, used the kitty box and is now sitting in the living room on his favourite chair.
Click to expand...
This is great. I just stopped by to see how Eddie was doing today. It sounds like he is much better! What a hard time he had. I know you are glad to have him home and I bet he is VERY glad to be home as well.
 
I just remembered yesterday that you mentioned on a different condo that Eddie has dental issues and that you weren't sure what to do since he cannot be anesthetized. I just wanted to mention how I handled this in a kitty who could not be anesthetized due to bad kidneys. We did one week on Antirobe (clindamycin) and three weeks off. This kept the teeth in check pretty well. You could ask your vet about it sometime.
 
Overall not too bad for having no/significantly less insulin the past few days. Do you know if they were giving Eddie his prednisolone while hospitalized? Just curious. You’ll be rebuilding the depot of course so keep that in mind as you make dosing decisions. Ongoing testing/data collection will be very important.

Hope both you and Eddie have gotten some rest.
 
Suzanne & Darcy said:
I just remembered yesterday that you mentioned on a different condo that Eddie has dental issues and that you weren't sure what to do since he cannot be anesthetized. I just wanted to mention how I handled this in a kitty who could not be anesthetized due to bad kidneys. We did one week on Antirobe (clindamycin) and three weeks off. This kept the teeth in check pretty well. You could ask your vet about it sometime.
Click to expand...

I've not heard of Antirobe. Do you think it is effective in regards a root without the tooth still in the jaw? He has a few of these bad dental issues.
 
JL and Chip said:
Overall not too bad for having no/significantly less insulin the past few days. Do you know if they were giving Eddie his prednisolone while hospitalized? Just curious. You’ll be rebuilding the depot of course so keep that in mind as you make dosing decisions. Ongoing testing/data collection will be very important.

Hope both you and Eddie have gotten some rest.
Click to expand...
I'm probably going to be increasing tonight but I'm going to go slowly, if only because of the SRT and the unknown territory as you so aptly put it the other day. They were giving him his prednisolone as I brought all of his medications to the hospital. If he missed any it would have been only one round in a day.

As for rebuilding the depot, can you explain further. If, for example, I increase tonight I was thinking of going from 2u to 3u or 4u. Does that make sense?
 
Suzanne & Darcy said:
This is great. I just stopped by to see how Eddie was doing today. It sounds like he is much better! What a hard time he had. I know you are glad to have him home and I bet he is VERY glad to be home as well.
Click to expand...

He is SO GLAD to be home. I can't get him off his chair or the couch in the living room. He's also letting me scratch beneath his chin, which he was very growly about in the last while.
 
Jodey&Eddie said:
I've not heard of Antirobe.
Click to expand...
Also called Clindamycin. Best AB for mouth infections. Tastes horrible, available liquid or pills. If you can pill him, go that way. Neko got the liquid, hated it. And definitely add a probiotic. It is really hard on tummy flora. Speaking from personal experience. :blackeye: What Suzanne is talking about is sometimes called pulse dosing of antibiotics.

As for dosing, SRT effect isn't that unpredictable. It's not like he needs 9 unit one day and the next it's 2 units. A drop to 8 would be a possibility. Cabergoline can be a much more drastic dose dropping scenario.

The depot needs around 6 cycles to see what a dose can do. I would definitely not hold this dose six cycles. It's clearly not enough insulin.
 
Jodey&Eddie said:
I've not heard of Antirobe. Do you think it is effective in regards a root without the tooth still in the jaw? He has a few of these bad dental issues.
Click to expand...
Clindamycin is very effective against bacteria found in the mouth. It’s just something you may want to discuss with your vet. Yes… pulse dosing
 
Wendy&Neko said:
Also called Clindamycin. Best AB for mouth infections. Tastes horrible, available liquid or pills. If you can pill him, go that way. Neko got the liquid, hated it. And definitely add a probiotic. It is really hard on tummy flora. Speaking from personal experience. :blackeye: What Suzanne is talking about is sometimes called pulse dosing of antibiotics.

As for dosing, SRT effect isn't that unpredictable. It's not like he needs 9 unit one day and the next it's 2 units. A drop to 8 would be a possibility. Cabergoline can be a much more drastic dose dropping scenario.

The depot needs around 6 cycles to see what a dose can do. I would definitely not hold this dose six cycles. It's clearly not enough insulin.
Click to expand...

So, an increase to 4u or 5u isn't unreasonable?
 
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