02/12 Eddie AMPS 256 +3 214 PMPS 283 +2 205 +3 139 +5 146

Copied from the sticky:
Increasing the dose:
Hold the dose for 3 - 5 days (6 - 10 consecutive cycles) if nadirs are less than 200 before increasing the dose by 0.25 unit.
if your cat is new to numbers under 200, it is recommended to hold the dose for at least 8-10 cycles before increasing.
when your cat starts to see nadirs under 100, hold the dose for at least 10 cycles before increasing.
Increase by 0.25 unit after 3 days (6 consecutive cycles) if nadirs are greater than 200, but less than 300.
Increase by 0.5 unit after 3 days (6 consecutive cycles) if nadirs are greater than 300.
 
Copied from the sticky:
Increasing the dose:
Hold the dose for 3 - 5 days (6 - 10 consecutive cycles) if nadirs are less than 200 before increasing the dose by 0.25 unit.
if your cat is new to numbers under 200, it is recommended to hold the dose for at least 8-10 cycles before increasing.
when your cat starts to see nadirs under 100, hold the dose for at least 10 cycles before increasing.
Increase by 0.25 unit after 3 days (6 consecutive cycles) if nadirs are greater than 200, but less than 300.
Increase by 0.5 unit after 3 days (6 consecutive cycles) if nadirs are greater than 300.

Ok, I'm going to have to sit with this for a bit. Thanks, Melissa. I had forgotten about the sticky and I see this is more complicated that how I've been looking at Eddie's SS.
 
I used a human meter, but my rule of thumb of how long to hold a dose with blue nadirs (note the plural) depended on how low the blue. Low blues got held the 10 cycles, high blues maybe up after 6.

Maybe blues again today?
 
I used a human meter, but my rule of thumb of how long to hold a dose with blue nadirs (note the plural) depended on how low the blue. Low blues got held the 10 cycles, high blues maybe up after 6.

Maybe blues again today?
Gosh, I had to be out for most of the day and didn't get to test until PMPS 283. What do you think of his nightshift blues in the last few nights? He's been on 7.75u for 5 days (do you count 1 day as one cycle? ).
This is where my inexperience shows.
 
do you count 1 day as one cycle?
Start the count at 1 for the first shot at that dose. That makes tonight cycle 10.

Those low blues he's been seeing at night are nice. Upper greens would be nicer. But this is where you have to decide what sort of nadirs you want him to have given how much you can monitor.
 
Start the count at 1 for the first shot at that dose. That makes tonight cycle 10.

Those low blues he's been seeing at night are nice. Upper greens would be nicer. But this is where you have to decide what sort of nadirs you want him to have given how much you can monitor.
Ok, I see, thank you, now I understand.
Hmmm, what sort of nadirs I want him to have. I don't think I've ever thought of it that way. I've just been watching for the earned reduction (although I've got it at 2x76 now as he kept rollercoastering with a reduction.
I think the part that I'm also not sure of is this: when he gets a nice blue, even an upper green, I am feeding and testing so that he doesn't crash. But by feeding him, I'm keeping him in the blue zone, am I not? And is the point not to keep trying to get the dose lower? Is there a contradiction with feeding vs seeking (if that's the right word) earned reductions?
Thank you.
 
For an acro, my goal was not to earn reductions, but rather to get them as regulated as possible. Mostly under renal threshold is a good goal, along with keeping them safe. Then if a reduction happens, it happens. That is not anything you have control over nor something you should try to force. That is up to the tumour and the SRT effect. With a non acro, the goal is to try to get them tightly regulated so their pancreas spends more time in green and heals. That isn't in play here - many acros already have working pancreases.
 
For an acro, my goal was not to earn reductions, but rather to get them as regulated as possible. Mostly under renal threshold is a good goal, along with keeping them safe. Then if a reduction happens, it happens. That is not anything you have control over nor something you should try to force. That is up to the tumour and the SRT effect. With a non acro, the goal is to try to get them tightly regulated so their pancreas spends more time in green and heals. That isn't in play here - many acros already have working pancreases.
Ok, this makes sense. I will carry on tonight as he’s going into blue. I’ll test again at +5.
Thank you, Wendy, for helping me to get clear on keeping them safe. How, though, does one determine the best renal threshold in their case?
 
Ju
For an acro, my goal was not to earn reductions, but rather to get them as regulated as possible. Mostly under renal threshold is a good goal, along with keeping them safe. Then if a reduction happens, it happens. That is not anything you have control over nor something you should try to force. That is up to the tumour and the SRT effect. With a non acro, the goal is to try to get them tightly regulated so their pancreas spends more time in green and heals. That isn't in play here - many acros already have working pancreases.
Just chiming in to say I agree with this wholeheartedly. My goal was never reductions, it was simply regulated BG. We simply do not have control over so much of this. Get them the best quality of life you can, anything else is a bonus. I was actually a bit excited each time I increased, because it meant closer to better numbers and him feeling better.

Jodey, I know with Eddie it must be triply frustrating given history. Focus on the cat and how he's doing, not the numbers or dose :bighug:
 
Ju

Just chiming in to say I agree with this wholeheartedly. My goal was never reductions, it was simply regulated BG. We simply do not have control over so much of this. Get them the best quality of life you can, anything else is a bonus. I was actually a bit excited each time I increased, because it meant closer to better numbers and him feeling better.

Jodey, I know with Eddie it must be triply frustrating given history. Focus on the cat and how he's doing, not the numbers or dose :bighug:
Thanks, Melissa. I appreciate the chiming. :)
With all that Eddie's gone through, the goal shifts at times. I think on the one hand I have reductions in mind because his brother, Blue, as you might know, also has/had acromegaly and surgery and radiation treatment, twice, and now he's totally OTJ. I guess I keep hoping that this could happen for Eddie.

Anyway, below are the results of his blood panel. Vet wants to do fructosamine and UPCR so that's to come.
 

Attachments

Back
Top