? 10/22 Eddie's Big Drop! AMPS 277 +4 86 +5 72 +8 104 Decrease?

Jodey&Eddie&Blue

Member Since 2021
Good morning, Eddie this morning. Is this nearing a dose reduction? He's doing so well. I did the +4 test and then gave him his lunch (about 4 large tsps of low carb).
 
With TR, reductions are earned when the BG drops below 50 (on a human meter) and 68 on a pet meter. For long term diabetics it's a drop below 40 on a human meter.

When was Eddie's diabetes diagnosis?

Please get a test at +5.

Does he get food between his shot and +4? Another snack at +2 may help with preventing those steep drops.
 
With TR, reductions are earned when the BG drops below 50 (on a human meter) and 68 on a pet meter. For long term diabetics it's a drop below 40 on a human meter.

When was Eddie's diabetes diagnosis?

Please get a test at +5.

Does he get food between his shot and +4? Another snack at +2 may help with preventing those steep drops.

We had a dose reduction on October 15 (see SS).

The thing is, Eddie is not officially diabetic. He has acromegaly, although he's had hypophysectomy and SRT. The SS fluctuations might be telling the story of the effect of SRT on the tumour and therefore the lessening of hormone release that results in "diabetes", as in insulin resistant.

I'm doing TR because I'm hoping to get a handle on regulation just in case the tumour has been eradicated and he goes hypo as a result of giving insulin.

Many acrocats who have not have surgery or SRT can require dosages over 40U BiD! The fact that Eddie is at such a "low" dose is encouraging.

I will get a +5 test. He had the test between his shot and lunch. Lunch was about 20 mins after the test.
 
Just did a +5 and Eddie (after eating at 11:45) is at 72.

I'm going to test again in 20 mins and perhaps give a few tsp of low carb food.
 
We are still in really decent numbers. Should I test again @ +11 and again @ PMPS. How should I determine about staying steady @ 13U versus a decrease? Is a decrease a good idea?
 
I'm going to tag @Wendy&Neko here as she's the acrokitty expert here. Those greens you got today are perfectly safe numbers and it looks like Eddie's coming back up, so I would not do a reduction but we'll see what Wendy has to say. I know Eddie is acro and my Ruby is not, but Ruby is on steroids which makes her BGs a bit unpredictable as well. If you look at her recent numbers on her spreadsheet, you'll see that I can usually avoid her dropping too low by feeding her when it's necessary. It's hard to know when that acro tumor will pulse, so the best thing you can do is test him when you can.
 
I'm going to tag @Wendy&Neko here as she's the acrokitty expert here. Those greens you got today are perfectly safe numbers and it looks like Eddie's coming back up, so I would not do a reduction but we'll see what Wendy has to say. I know Eddie is acro and my Ruby is not, but Ruby is on steroids which makes her BGs a bit unpredictable as well. If you look at her recent numbers on her spreadsheet, you'll see that I can usually avoid her dropping too low by feeding her when it's necessary. It's hard to know when that acro tumor will pulse, so the best thing you can do is test him when you can.

Yes, he is coming back up slightly but he's also eaten twice since breakfast at 8:15, which was the AMPS time.

Eddie also takes Prednisolone, which he will have to take for the rest of his life because of removal of the pituitary. I'm looking into giving it to him twice a day in smaller doses instead of one large dose (1.25 mg) just before bed, which might be contributing to the higher number @ AMPS, because steroids.

I've just given him dinner post +8 104 so we'll see what he does between +8 and PMPS.

Thank you!
 
I personally would not decrease yet, but see what Wendy says. Numbers are still good, it looks like this dose might be starting to do some work, want him in these numbers as long as possible. A premature reduction could lose these numbers, if the IAA is still around you risk antibodies grabbing hold and running the BGs up as well.

Are you using 70 as a reduction point? Or the standard 50?
 
The thing is, Eddie is not officially diabetic. He has acromegaly
Actually, Eddie is diabetic. There is more than one type of diabetes, acromegaly falls under the "other types of diabetes" category, sometimes called type 3. In case you are interested, more details in this paper:
What’s in a Name? Classification of Diabetes Mellitis in Veterinary Medicine and Why it Matters: J Vet Intern Med 2016, Gilor, Niessen, Furrow, DiBartola
Are you using 70 as a reduction point? Or the standard 50?
She's using an AT, the 70/50 are for human meters. But 72 AT is very close to 68. I would tend to use an abundance of caution at this point. Eddie has had a couple reductions already within the last couple weeks. I suspect the SRT might be impacting him. I think I would reduce down to 12 units and see how he does. If it turns out his numbers don't come down, you can always take him back up. But that's much easier on the caregiver than fighting a larger depot if/when he next earns a reduction.
 
Jodey I just wanted to mention since I see you also posting on the Facebook acro group as well - not everyone is members of both this forum and that Facebook group (or any other groups you may be in), so we won't see the opinions given on each site. For the most part the advice has seemed to be pretty consistent, but I imagine if he starts to come down in numbers/dose it might start differing a bit.
 
Jodey I just wanted to mention since I see you also posting on the Facebook acro group as well - not everyone is members of both this forum and that Facebook group (or any other groups you may be in), so we won't see the opinions given on each site. For the most part the advice has seemed to be pretty consistent, but I imagine if he starts to come down in numbers/dose it might start differing a bit.
I post on both since I started there and they are for the most part consistent. I take my cue here.
 
I personally would not decrease yet, but see what Wendy says. Numbers are still good, it looks like this dose might be starting to do some work, want him in these numbers as long as possible. A premature reduction could lose these numbers, if the IAA is still around you risk antibodies grabbing hold and running the BGs up as well.

Are you using 70 as a reduction point? Or the standard 50?
This is a really good point about premature reduction.
I don't have a reduction point, actually. I've just been going on advice from this forum, especially with regards acromegaly and diabetes.
 
Actually, Eddie is diabetic. There is more than one type of diabetes, acromegaly falls under the "other types of diabetes" category, sometimes called type 3. In case you are interested, more details in this paper:
What’s in a Name? Classification of Diabetes Mellitis in Veterinary Medicine and Why it Matters: J Vet Intern Med 2016, Gilor, Niessen, Furrow, DiBartola

She's using an AT, the 70/50 are for human meters. But 72 AT is very close to 68. I would tend to use an abundance of caution at this point. Eddie has had a couple reductions already within the last couple weeks. I suspect the SRT might be impacting him. I think I would reduce down to 12 units and see how he does. If it turns out his numbers don't come down, you can always take him back up. But that's much easier on the caregiver than fighting a larger depot if/when he next earns a reduction.

@Wendy&Neko because we have gone up into the yellow zone, again, I will see what tomorrow brings about doing a reduction. I agree I think the SRT is impacting him but and I will reduce tomorrow if the pattern is the same.
Thank you.
 
This is a really good point about premature reduction.
I don't have a reduction point, actually. I've just been going on advice from this forum, especially with regards acromegaly and diabetes.
It may help you to have a hard cutoff, where yes absolutely when he drops below this number reduce. But there's also a bit of "art" with acro cats.coming down, looking at the overall recent trend and saying hey...we didn't exactly go below the cutoff, but something is going on here it may be better to reduce to get ahead of things (like Wendy said). I saw Facebook was also split to hold vs reduce to 12 haha

Wendy brought up the AlphaTrak and she's right, mistake on my part for missing that. I agree with her that the 72 on the AlphaTrak is close enough, especially without tests after that....any lower and you don't really have wiggle room at all.
 
You are so right about the "hey...something is going on here" and having this thought in mind, I will take that reduction tomorrow. I like what Wendy (and you) have said about getting ahead of things. It's a wave, I think...

Again, I was on the FB acromegaly group for a couple of years and they have been great with regards Blue (Eddie's brother with acro as well but who is in remission). I learned about this forum from someone on the FB group. They are not always consistent with their advice but I keep in contact with them, nevertheless.

Once i found this group, I felt more confident about consistency so, here I am.

Let's see what tomorrow brings. I feel there is something going on with Eddie. He seems so much more social and even content.

Thank you and goodnight.
 
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