Katherine&Ruby
Member Since 2020
https://www.felinediabetes.com/FDMB...192-3-182-8-146-10-202-pmps-182-2-191.253275/
We had an appointment with Ruby’s oncologist this morning and now she’s doing her post-onco dipsy doodle.
DBF is home with her and fed her a smidge of HC at +8 and I told him to hold off until I got home for shot time.
I relayed all of the drama of the past two weeks to the doctor. She said despite all that was going on Ruby is doing well. She’s gained more weight and so she did not see the need to do an ultrasound.
@Wendy&Neko I asked about chlorambucil again and why she is choosing not to use it with Ruby yet. She said because Ruby’s clinical signs are fine, because she doesn’t want to give more meds than necessary, because she doesn’t want to create the need for more vet visits as chemo might entail. She also said that prednisolone, while not a traditional chemo drug, has been proven to cause apoptosis or programmed cell death with lymphocytes. Not only does it have anti-inflammation properties but it can also stop the lymphoma from progressing. Pred does not work on all cancers, like breast cancer tumors, for example, but it has been shown to work with lymphoma. I found this bit of information useful and heartening.
We had an appointment with Ruby’s oncologist this morning and now she’s doing her post-onco dipsy doodle.
DBF is home with her and fed her a smidge of HC at +8 and I told him to hold off until I got home for shot time. I relayed all of the drama of the past two weeks to the doctor. She said despite all that was going on Ruby is doing well. She’s gained more weight and so she did not see the need to do an ultrasound.
@Wendy&Neko I asked about chlorambucil again and why she is choosing not to use it with Ruby yet. She said because Ruby’s clinical signs are fine, because she doesn’t want to give more meds than necessary, because she doesn’t want to create the need for more vet visits as chemo might entail. She also said that prednisolone, while not a traditional chemo drug, has been proven to cause apoptosis or programmed cell death with lymphocytes. Not only does it have anti-inflammation properties but it can also stop the lymphoma from progressing. Pred does not work on all cancers, like breast cancer tumors, for example, but it has been shown to work with lymphoma. I found this bit of information useful and heartening.
Almost three months on pred, those symptoms should be gone by now. To me those are clinical signs that the lymphoma is not being treated. And killing the lymphocytes is indeed the role of pred, think of it as mop up duty. However, what you really want to do is treat the disease (lymphoma) that is producing the excess lymphocytes. That's what chlorambucil does. At some point when the lymphoma progresses enough, the prednisolone will no longer be able to keep up with the amount of lymphocytes produced. As far as blood work goes, you wouldn't have to go into AMC each time for a checkup, you could have it done at your regular vet or even acupuncture vet and send the results to AMC.
